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Dynamics of Intermittent Synchronization of Neural Activity

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Book cover Advances in Dynamics, Patterns, Cognition

Part of the book series: Nonlinear Systems and Complexity ((NSCH,volume 20))

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Abstract

Neural activity of individual neurons and neuronal populations frequently exhibits synchronized dynamics. This synchronization has been related to a number of functions and dysfunctions of the brain. Synchronization of neural activity in the brain is rarely perfect. Rather, it exhibits intermittent dynamics, where episodes of synchrony are interspersed with episodes of non-synchronized activity. We review the recent developments in the studies of the intermittent neural synchrony with the focus on the analysis of the desynchronized dynamics. The application of the new analysis techniques to recordings of neural activity in different experiments suggests that different neural systems in the brain favor dynamics with short (although potentially numerous) desynchronization intervals. We further discuss the utility of this analysis in the study of neural systems and the potential functional significance of short desynchronization dynamics in the brain.

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References

  1. Abarbanel, H.D.I., Huerta, R., Rabinovich, M.I., Rulkov N.F., Rowat P.F., Selverston A.I.: Synchronized action of synaptically coupled chaotic model neurons. Neural Comput. 8, 1567–1602 (1996)

    Article  Google Scholar 

  2. Abarbanel, H.D.I., Rabinovich, M.I., Selverston, A., Bazhenov, M.V., Huerta, R., Sushchik, M.M., Rubchinskii, L.L.: Synchronization in neural networks. Phys. Usp. 39, 337–362 (1996)

    Article  Google Scholar 

  3. Ahn, S., Park, C., Rubchinsky, L.L.: Detecting the temporal structure of intermittent phase locking. Phys. Rev. E 84, 016201 (2011)

    Article  Google Scholar 

  4. Ahn, S., Rubchinsky, L.L.: Short desynchronization episodes prevail in synchronous dynamics of human brain rhythms. Chaos 23, 013138 (2013)

    Article  MathSciNet  Google Scholar 

  5. Ahn, S., Rubchinsky, L.L., Lapish, C.C.: Dynamical reorganization of synchronous activity patterns in prefrontal cortex-hippocampus networks during behavioral sensitization. Cereb. Cortex 24 (10), 2556–2561 (2014)

    Article  Google Scholar 

  6. Ahn, S., Solfest, J., Rubchinsky, L.L.: Fine temporal structure of cardiorespiratory synchronization. Am. J. Physiol. Heart Circ. Physiol. 306, 755–763 (2014)

    Article  Google Scholar 

  7. Bazhenov, M., Stopfer, M., Rabinovich, M., Huerta, R., Abarbanel, H.D.I., Sejnowski, T.J., Laurent, G.: Model of transient oscillatory synchronization in the locust antennal lobe. Neuron 30, 553–567 (2001)

    Article  Google Scholar 

  8. Buzsáki, G., Draguhn, A.: Neuronal oscillations in cortical networks. Science 304, 1926–1929 (2004)

    Article  Google Scholar 

  9. Dovzhenok, A., Park, C., Worth R.M., Rubchinsky L.L.: Failure of delayed feedback deep brain stimulation for intermittent pathological synchronization in Parkinson’s disease. PLoS One 8, e58264 (2013)

    Article  Google Scholar 

  10. Elson, R.C., Selverston, A.I., Huerta, R., Rulkov, N.F., Rabinovich, M.I., Abarbanel, H.D.I.: Synchronous behavior of two coupled biological neurons. Phys. Rev. Lett. 81, 5692–5695 (1998)

    Article  Google Scholar 

  11. Engel, A.K., Fries, P., Singer, W.: Dynamic predictions: oscillations and synchrony in top-down processing. Nat. Rev. Neurosci. 2, 704–716 (2001)

    Article  Google Scholar 

  12. Fell, J., Axmacher, N.: The role of phase synchronization in memory processes. Nat. Rev. Neurosci. 12, 105–118 (2011)

    Article  Google Scholar 

  13. Fries, P.: Rhythms for cognition: communication through coherence. Neuron 88 (1), 220–235 (2015)

    Article  Google Scholar 

  14. Gong, P., Nikolaev, A.R., Leeuwen, C.V.: Intermittent dynamics underlying the intrinsic fluctuations of the collective synchronization patterns in electrocortical activity. Phys. Rev. E 76, 011904 (2007)

    Article  Google Scholar 

  15. Hramov, A.E., Koronovskii, A.A., Midzyanovskaya, I.S., Sitnikova, E., Rijn, C.M.V.: On-off intermittency in time series of spontaneous paroxysmal activity in rats with genetic absence epilepsy. Chaos 16, 043111 (2006)

    Article  MATH  Google Scholar 

  16. Murthy, V.N., Fetz, E.E.: Oscillatory activity in sensorimotor cortex of awake monkeys: synchronization of local field potentials and relation to behavior. J. Neurophysiol. 76 (6), 3949–3967 (1996)

    Google Scholar 

  17. Nowotny, T., Zhigulin, V.P., Selverston, A.I., Abarbanel, H.D.I., Rabinovich, M.I.: Enhancement of synchronization in a hybrid neural circuit by spike-timing dependent plasticity. J. Neurosci. 23 (30), 9776–9785 (2003)

    Google Scholar 

  18. Nowotny, T., Huerta, R., Rabinovich, M.I.: Neuronal synchrony: peculiarity and generality. Chaos 18, 037119 (2008)

    Article  MathSciNet  Google Scholar 

  19. Park, C., Rubchinsky, L.L.: Intermittent synchronization in a network of bursting neurons. Chaos 21, 033125 (2011)

    Article  MathSciNet  Google Scholar 

  20. Park, C., Rubchinsky, L.L.: Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia. PLoS One 7 (12), e51530 (2012)

    Article  Google Scholar 

  21. Park, C., Worth, R.M., Rubchinsky, L.L.: Fine temporal structure of beta oscillations synchronization in subthalamic nucleus in Parkinson’s disease. J. Neurophysiol. 103, 2707–2716 (2010)

    Article  Google Scholar 

  22. Park, C., Worth, R.M., Rubchinsky, L.L.: Neural dynamics in Parkinsonian brain: the boundary between synchronized and nonsynchronized dynamics. Phys. Rev. E 83, 042901 (2011)

    Article  Google Scholar 

  23. Pikovsky, A., Rosenblum, M., Kurths, J.: Synchronization: A Universal Concept in Nonlinear Sciences. Cambridge University Press, Cambridge (2001)

    Book  MATH  Google Scholar 

  24. Rabinovich, M.I., Huerta R., Laurent G: Transient dynamics for neural processing. Science 321, 48–50 (2008)

    Article  Google Scholar 

  25. Rabinovich, M.I., Varona, P., Selverston, A.I., Abarbanel, H.D.I.: Dynamical principles in neuroscience. Rev. Mod. Phys. 78, 1213–1265 (2006)

    Article  Google Scholar 

  26. Rabinovich, M.I., Simmons, A.N., Varona, P.: Dynamical bridge between brain and mind. Trends Cogn. Sci. 19, 453–461 (2015)

    Article  Google Scholar 

  27. Ratnadurai-Giridharan, S., Zauber, S.E., Worth, R.M., Witt, T., Ahn, S., Rubchinsky, L.L.: Temporal patterning of neural synchrony in the basal ganglia in Parkinson’s disease. Clin. Neurophysiol. 127, 1743–1745 (2016)

    Article  Google Scholar 

  28. Rosenblum, M.G., Pikovsky, A.S., Kurth, J.: Comment on phase synchronization in discrete chaotic systems. Phys. Rev. E 63, 058201 (2001)

    Article  Google Scholar 

  29. Rubchinsky, L.L., Park, C., Worth R.M.: Intermittent neural synchronization in Parkinson’s disease. Nonlinear Dyn. 68, 329–346 (2012)

    Article  Google Scholar 

  30. Rubchinsky, L.L., Ahn, S., Park, C.: Dynamics of desynchronized episodes in intermittent synchronization. Front. Phys. 2, 38 (2014)

    Article  Google Scholar 

  31. Sanes, J.N., Donoghue, J.P.: Oscillations in local field potentials of the primate motor cortex during voluntary movement. Proc. Natl. Acad. Sci. U. S. A. 90, 4470–4474 (1993)

    Article  Google Scholar 

  32. Schnitzler, A., Gross, J.: Normal and pathological oscillatory communication in the brain. Nat. Rev. Neurosci. 6, 285–296 (2005)

    Article  Google Scholar 

  33. Szücs, A., Huerta, R., Rabinovich, M.I., Selverston, A.I.: Robust microcircuit synchronization by inhibitory connections. Neuron 61, 439–453 (2009)

    Article  Google Scholar 

  34. Uhlhaas, P.J., Singer, W.: Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology. Neuron 52, 155–168 (2006)

    Article  Google Scholar 

  35. Uhlhaas, P.J., Singer, W.: Abnormal neural oscillations and synchrony in schizophrenia. Nat. Rev. Neurosci. 11, 100–113 (2010)

    Article  Google Scholar 

  36. Velazquez, J.L., Khosravani, H., Lozano, A., Bardakjian, B.L., Carlen, P.L., Wennberg, R.: Type III intermittency in human partial epilepsy. Eur. J. Neurosci. 11 (7), 2571–2576 (1999)

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Mathematical Sciences, Indiana University Purdue University Indianapolis, Indianapolis, IN, 46202, USA

    Leonid L. Rubchinsky

  2. Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, 46202, USA

    Leonid L. Rubchinsky

  3. Department of Mathematics, North Carolina A&T State University, Greensboro, NC, USA

    Choongseok Park

  4. Department of Mathematics, East Carolina University, Greenville, NC, USA

    Sungwoo Ahn

Authors
  1. Leonid L. Rubchinsky
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  2. Choongseok Park
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  3. Sungwoo Ahn
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Correspondence to Leonid L. Rubchinsky .

Editor information

Editors and Affiliations

  1. Pennsylvania State University, University Park, Pennsylvania, USA

    Igor S. Aranson

  2. Institute for Physics and Astronomy, University of Potsdam, Potsdam, Germany

    Arkady Pikovsky

  3. BioCircuits Institute, University of California San Diego, La Jolla, California, USA

    Nikolai F. Rulkov

  4. BioCircuits Institute, University of California San Diego, La Jolla, California, USA

    Lev S. Tsimring

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Rubchinsky, L.L., Park, C., Ahn, S. (2017). Dynamics of Intermittent Synchronization of Neural Activity. In: Aranson, I., Pikovsky, A., Rulkov, N., Tsimring, L. (eds) Advances in Dynamics, Patterns, Cognition. Nonlinear Systems and Complexity, vol 20. Springer, Cham. https://doi.org/10.1007/978-3-319-53673-6_16

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  • DOI: https://doi.org/10.1007/978-3-319-53673-6_16

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-53673-6

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