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Things Aren’t Always What They Seem: The Case of Hala

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Abstract

An 8-year-old Syrian girl came to our department with fever and severe skin lesions over her legs. The initial diagnoses were post-traumatic burns due to explosives, complicated by sepsis and unsuccessful initial management in Syria. It became apparent that the true diagnosis was a rare genetic disease, leukocyte adhesion defect (LAD) type I complicated by a severe skin disease pyoderma gangrenosum. Bone marrow transplantation was arranged in an appropriate centre.

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References

  1. Van de Kerkhof PC, Weemaes CM. Skin manifestations in congenital deficiency of leucocyte-adherence glycoproteins (CDLG). Br J Dermatol. 1990;123:395–401.

    Article  PubMed  Google Scholar 

  2. Bedlow AJ, Davies EG, Moss AL, et al. Pyoderma gangrenosum in a child with congenital partial deficiency of leucocyte adherence glycoproteins. Br J Dermatol. 1998;139:1064–7.

    Article  CAS  PubMed  Google Scholar 

  3. Hinze CH, Lucky AW, Bove KE, et al. Leukocyte adhesion deficiency type 1 presenting with recurrent pyoderma gangrenosum and flaccid scarring. Pediatr Dermatol. 2010;27:500–3.

    Article  PubMed  Google Scholar 

  4. Thakur N, Sodani R, Chandra J, Singh V. Leukocyte adhesion defect type 1 presenting with recurrent pyoderma gangrenosum. Indian J Dermatol. 2013;58:158–60.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Madkaikar M, Italia K, Gupta M, et al. Leukocyte adhesion deficiency-I with a novel intronic mutation presenting with pyoderma gangrenosum-like lesions. J Clin Immunol. 2015;35:43–4.

    Article  Google Scholar 

  6. Van de Vijver E, Van den Berg TK, Kuijpers TW. Leukocyte adhesion deficiencies. Hematol Oncol Clin N Am. 2013;27:101–16.

    Article  Google Scholar 

  7. Crowley CA, Curnutte JT, Rosin RE, et al. An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med. 1980;302(21):1163–8.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Anthony Luder .

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Luder, A. (2017). Things Aren’t Always What They Seem: The Case of Hala. In: Zarka, S., Lerner, A. (eds) Complicated War Trauma and Care of the Wounded . Springer, Cham. https://doi.org/10.1007/978-3-319-53339-1_6

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  • DOI: https://doi.org/10.1007/978-3-319-53339-1_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-53338-4

  • Online ISBN: 978-3-319-53339-1

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