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The Impact of IGRT on Normal Tissue Toxicity

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Book cover Advances in Radiation Oncology

Part of the book series: Cancer Treatment and Research ((CTAR))

Abstract

Image Guided Radiation Therapy (IGRT) deploys advanced imaging techniques prior to each treatment to ensure the highest possible agreement between the planned treatment geometry and the daily set-up. This agreement includes both the patient position and the localization of the internal target and normal structures. This process reduces non-tumor tissues within the target volume to a minimum. IGRT is now commonly accompanied by altered fractionation schemes, usually hypofractionation. With the small-volume, high-dose-per-fraction treatments, the profile of treatment morbidities may change, compared to conventional 3D treatment. This chapter explores how these morbidities may change with the use of IGRT.

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Notes

  1. 1.

    Only recently has de-escalation of target dose become a serious line of investigation in radiation oncology.

  2. 2.

    In this chapter, IGRT will be assumed to include daily volumetric imaging prior to treatment. Early definitions of IGRT included multimodality imaging to define better the target volume. In this chapter, we will consider only the impact of daily imaging on NT responses. In IGRT like in quantum mechanics, we assume you know where something is only when you look for it.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, City of hope, 1500 East Durate Road, Durate, CA, 91010, USA

    Timothy E. Schultheiss

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  1. Timothy E. Schultheiss
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Correspondence to Timothy E. Schultheiss .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, City of Hope, Duarte, California, USA

    Jeffrey Y.C. Wong

  2. Department of Radiation Oncology, Division of Radiation Physics, City of Hope, Duarte, California, USA

    Timothy E. Schultheiss

  3. Department of Radiation Oncology, City of Hope, Duarte, California, USA

    Eric H. Radany

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Schultheiss, T.E. (2017). The Impact of IGRT on Normal Tissue Toxicity. In: Wong, J., Schultheiss, T., Radany, E. (eds) Advances in Radiation Oncology. Cancer Treatment and Research. Springer, Cham. https://doi.org/10.1007/978-3-319-53235-6_7

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  • DOI: https://doi.org/10.1007/978-3-319-53235-6_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-53233-2

  • Online ISBN: 978-3-319-53235-6

  • eBook Packages: MedicineMedicine (R0)

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