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Proteomic Approaches for Diagnostics of Canine and Feline Dementia

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Canine and Feline Dementia

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Abstract

Cognitive dysfunction syndrome (CDS) in pet animals constitutes a pressing problem of the modern society. Millions of senior dogs and cats undergo age-related behavioral changes that impact their social interactions. Currently, it is difficult to discriminate between normal aging and dementing processes. The situation is akin to that in humans; however, human medicine receives enormous resources that resulted in a set of current diagnostic criteria including a number of dementia assessing scales, diagnostic assays, and novel potential biomarkers. While animal well-being is not in the limelight of societal interest, the dementia diagnostics starts to catch up. Nevertheless, biochemical markers related to the animal dementia are underdeveloped, despite the fact that dogs and cats provide natural models for human dementia.

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Acknowledgment

The authors received funding by APVV-0399-10, APVV-15-0613, and APVV-14-0872 and VEGA grants 2/0155/13 and 2/0164/16.

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  1. Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska 9, Bratislava, Slovak Republic

    Branislav Kovacech, Monika Zilkova, Jozef Hanes & Rostislav Skrabana

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  1. Branislav Kovacech
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  3. Jozef Hanes
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Correspondence to Monika Zilkova .

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  1. North Toronto Veterinary Behaviour, Specialty Clinic, Thornhill, Ontario, Canada

    Gary Landsberg

  2. Univ of Veterinary Medicine and Pharmacy, Small Animal Clinic, Košice, Slovakia

    Aladár Maďari

  3. Slovak Academy of Sciences, Institute of Neuroimmunology, Bratislava, Slovakia

    Norbert Žilka

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Kovacech, B., Zilkova, M., Hanes, J., Skrabana, R. (2017). Proteomic Approaches for Diagnostics of Canine and Feline Dementia. In: Landsberg, G., Maďari, A., Žilka, N. (eds) Canine and Feline Dementia. Springer, Cham. https://doi.org/10.1007/978-3-319-53219-6_7

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