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New Approach for the Electrochemical Detection of Dopamine

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  • First Online:
International Conference on Advancements of Medicine and Health Care through Technology; 12th - 15th October 2016, Cluj-Napoca, Romania

Part of the book series: IFMBE Proceedings ((IFMBE,volume 59))

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Abstract

An innovative biomimetic electrochemical sensor was elaborated for the dopamine detection using a glassy carbon electrode modified with gold nanoparticles. The molecularly imprinted polymers and nonimprinted polymers were electrochemically generated on the electrode surface after the obtaining of the self-assembled monolayer of the functional monomer - p-aminothiophenol through sulfur-gold bonds with dopamine as template molecule (in the case of molecularly imprinted polymer). Cyclic voltammetry and electrochemical impedance spectroscopy were used for the characterization of the sensor considering its response in the presence of hexacyanoferrate as redox probe, while the morphostructural characterization of the elaborated platform was realized by using atomic force microscopy. Differential pulse voltammetry experiments in saline phosphate buffer (0.02M; pH 7.4) were performed after the pre-concentration of dopamine in order to test the biomimetic sensor performance.

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Author information

Authors and Affiliations

  1. Analytical Chemistry Department, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 4 Louis Pasteur St., 400349, Cluj-Napoca, Romania

    M. Tertiș, A. Florea, A. Adumitrachioaie, C. Cristea & R. Săndulescu

  2. National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat St., 400293, Cluj-Napoca, Romania

    D. Bogdan

Authors
  1. M. Tertiș
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  2. A. Florea
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  3. A. Adumitrachioaie
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  4. D. Bogdan
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  5. C. Cristea
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  6. R. Săndulescu
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Corresponding author

Correspondence to C. Cristea .

Editor information

Editors and Affiliations

  1. Faculty of Electrical Engineering, Technical University of Cluj-Napoca, Cluj-Napoca, Romania

    Simona Vlad

  2. Faculty of Electrical Engineering, Technical University of Cluj-Napoca Faculty of Electrical Engineering, Cluj-Napoca, Romania

    Nicolae Marius Roman

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Tertiș, M., Florea, A., Adumitrachioaie, A., Bogdan, D., Cristea, C., Săndulescu, R. (2017). New Approach for the Electrochemical Detection of Dopamine. In: Vlad, S., Roman, N. (eds) International Conference on Advancements of Medicine and Health Care through Technology; 12th - 15th October 2016, Cluj-Napoca, Romania. IFMBE Proceedings, vol 59. Springer, Cham. https://doi.org/10.1007/978-3-319-52875-5_23

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  • DOI: https://doi.org/10.1007/978-3-319-52875-5_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-52874-8

  • Online ISBN: 978-3-319-52875-5

  • eBook Packages: EngineeringEngineering (R0)

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