Abstract
This chapter describes the versatility of marine microorganisms. They have inherent ability to grow and thrive under polyextremes. The bioactive compounds such as hydrolases, unique pigments, alkaloids, peptides, colored antibiotics, exopolysaccharides, siderophores, ectoine, and proteins produced and released under stressful conditions have potential biotechnological applications especially in agriculture, food, health care, and medicine. We have also discussed the possible applications of polyextremophiles in the treatment of cancer and neurodegenerative diseases.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Ahmad A, Usup G, Mohamad S, Yahya AN, Jafarzade M (2013) Isolation and characterization of pigmented bacteria showing antimicrobial activity from Malaysian marine environment. Malays J Microbiol 9:152–160 https://doaj.org/article/6a0cf251c31c4b0281a8d6500d07fee6
Babu P, Chandel AK, Singh PV (2015) Survival mechanisms of extremophiles, Chap. 2. In: Babu P (ed) Extremophiles and their applications in medical processes. Extremophilic bacteria. Springer International Publishing, Cham, pp 9–23. doi:10.1007/978-3-319-12808-5
Becker MH, Brucker RM, Schwantes CR, Harris RN, Minbiole KPC (2009) The bacterially produced metabolite violacein is associated with survival of amphibians infected with a lethal fungus. Appl Environ Microbiol 71:6635–6638. doi:10.1128/AEM.01294-09
Calderon MI, Vargas C, Rojo F, Iglesias-Guerra F, Csonka LN, Ventosa A, Nieto JJ (2004) Complex regulation of the synthesis of the compatible solute ectoine in the halophilic bacterium Chromohalobacter salexigens DSM 3043 T. Microbiology 150:3051–3063. doi:10.1099/mic.0.27122-0
Copeland WE, Wolke D, Angold A, MRCPsych, Costello EJ (2013) Adult psychiatric and suicide outcomes of bullying and being bullied by peers in childhood and adolescence. JAMA Psychiatry 70:419–426. doi:10.1001/jamapsychiatry.2013.504
Corinaldesi C (2015) New perspectives in benthic deep-sea microbial ecology. Front Mar Sci 2:17. doi:10.3389/fmars.2015.00017
Dalmaso GZL, Ferreira D, Vermelho AB (2015) Marine extremophiles: a source of hydrolases for biotechnological applications. Mar Drugs 13:1925–1965. doi:10.3390/md13041925
Davila AF, Gómez-Silva B, Asunción de los Rios, Ascaso C, Olivares H, McKay CP, Wierzchos J (2008) Facilitation of endolithic microbial survival in the hyperarid core of the Atacama Desert by mineral deliquescence. J Geophy Res 113:G01028. doi:10.1029/2007JG000561
Delbarre-ladrat C, Sinquin C, Lebellenger L, Zykwinska A, Colliec-jouault S (2014) Exopolysaccharides produced by marine bacteria and their applications as glycosaminoglycan-likemolecules. Front Chem 2:85. doi:10.3389/fchem.2014.00085
Donot F, Fontana A, Baccou JC, Schorr-Galindo S (2012) Microbial exopolysaccharides: main examples of synthesis, excretion, genetics and extraction. Carbohydr Polym 87:951–962. doi:10.1016/j.carbpol.2011.08.083
Falcicchio P, Wolterink Van-Loo S, Franseen MCR, van deer Oost J (2014) DHAP-dependent aldolases from (hyper) thermophiles: biochemistry and applications. Extremophiles 18:1–13. doi:10.1007/s00792-013-0593-x
Feher D, Barlow RS, Lorenzo PS, Hemscheidt TK (2008) A 2-substituted prodiginine, 2-(p-hydroxybenzyl) prodigiosin, from Pseudoalteromonas rubra. J Nat Pro 71:1970–1972. doi:10.1021/np800493p
Finore I, Didonato P, Mastascusa V, Nicolaus B, Poli A (2014) Fermentation technologies for the optimization of marine microbial exopolysaccharide production. Mar Drugs 12:3005–3024. doi:10.3390/md12053005
Freitas F, Alves VD, Reis MAM (2011) Advances in bacterial exopolysaccharides: from production to biotechnological applications. Trends Biotechnol 29:388–398. doi:10.1016/j.tibtech.2011.03.008
Gomes J, Steiner W (2004) The biocatalytic potential of extremophiles and extremozymes. Food Technol Biotechnol 42:223–235 http://www.ftb.com.hr/images/pdfarticles/2004/October-December/42-223.pdf
Graf R, Anzali S, Buenger J, Pfluecker F, Driller H (2008) The multifunctional role of ectoine as a natural cell protectant. Clin Dermatol 26:326–333. doi:10.1016/j.clindermatol.2008.01.002
Irwin JA, Baird AW (2004) Extremophiles and their application to veterinary medicine. Ir Vet J 57:348–354. doi:10.1186/2046-0481-57-6-348
Kanapathipillai M, Lentzen G, Sierks M, Park CB (2005) Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer’s b-amyloid. FEBS Lett 579:4775–4780. doi:10.1016/j.febslet.2005.07.057
Kim D, Lee JS, Park YK et al (2007) Biosynthesis of antibiotic prodiginines in the marine bacterium Hahella chejuensis KCTC 2396. J Appl Microbiol 102:937–944. doi:10.1111/j.1365-2672.2006.03172.x
Kuhlmann AU, Hoffmann T, Bursy J, Jebbar M, Bremer E (2011) Ectoine and hydroxyectoine as protectants against osmotic and cold stress: uptake through the SigB-controlled Betaine-Choline-Carnitine transporter-type carrier EctT from Virgibacillus pantothenticus. J Bacteriol 193:4699–4708. doi:10.1128/JB.05270-11
Lee JH, Kim YS, Choi TJ, Lee WJ, Kim YT (2004) Paracoccus haeundaensis sp. nov. a gram-negative, halophilic, astaxanthin-producing bacterium. Int J Syst Evol Microbiol 54:1699–1702. doi:10.1099/ijs.0.63146-0
Matz C, Deines P, Boenigk J, Arndt H, Eberl L, Kjelleberg S, Jürgens K (2004) Impact of violacein producing bacteria on survival and feeding of bacterivorous nanoflagellates. Appl Environ Microbiol 70:1593–1599. doi:10.1128/AEM.70.3.1593-1599.2004
Mayer AM, Glaser KB, Cuevas C, Jacobs RS, Kem W, Little RD, McIntosh JM, Newman DJ, Potts BC, Shuster DE (2010) The odyssey of marine pharmaceuticals: a current pipeline perspective. Trends Pharmacol Sci 31:255–265. doi:10.1016/j.tips.2010.02.005
Mehta A, Sidhu C, Pinnaka AK, Roy Choudhury A (2014) Extracellular polysaccharide production by a novel osmotolerant marine strain of Alteromonas macleodii and its application towards biomineralization of silver. PLoS One 9:e98798. doi:10.1371/journal.pone.0098798
Mergeay M, Monchya S, Vallaeys T, Auquier A, Benotman A, Bertin P, Taghavi S, Dunn J, van der Lelie D, Wattiez R (2003) Ralstonia metallidurans, a bacterium specifically adapted to toxic metals: towards a catalogue of metal-responsive genes. FEMS Microbiol Rev 27:385–410. doi:10.1016/S0168-6445(03)00045-7
Nakashima T, Kurachi M, Kato Y, Yamaguchi K, Oda T (2005) Characterization of bacterium isolated from the sediment at coastal area of Omura bay in Japan and several biological activities of pigment produced by this isolate. Microbiol Immunol 49:407–415. doi:10.1111/j.1348-0421.2005.tb03744.x
Neifar M, Maktouf S, Ghorbel RE, Jaouani A, Cherif A (2015) Extremophiles as source of bioactive compounds with industrial applications, Chap. 10. In: Gupta VK, Tuohy MG, Lohani M, O’Donovan A (eds) Biotechnology and bioactive compounds: sources and applications, 1st edn. Wiley, Hoboken, NJ. doi:10.1002/9781118733103.ch10
Nicolaus B, Kambourova M, Oner ET (2010) Exopolysaccharides from extremophiles: from fundamentals to biotechnology. Environ Technol 31:1145–1158. doi:10.1080/09593330903552094
Radianingtyas H, Wright FC (2003) Alcohol dehydrogenases from thermophilic and hyperthermophilic archaea and bacteria. FEMS Microbiol Rev 27:593–616. doi:10.1016/S0168-6445(03)00068-8
Shieh WY, Chen YW, Chaw SM, Chiu HH (2003) Vibrio ruber sp. nov. a red, facultatively anaerobic, marine bacterium isolated from sea water. Int J Syst Evol Microbiol 53:479–484. doi:10.1099/ijs.0.02307-0
Simon-Colin C, Gueguen Y, Bachere E, Kouzayha A, Saulnier D, Gayet N, Guezennec J (2015) Use of natural antimicrobial peptides and bacterial biopolymers for cultured pearl production. Mar Drugs 13:3732–3744. doi:10.3390/md13063732
Soliev A, Hosokawa K, Enomoto K (2011) Bioactive pigments from marine bacteria: applications and physiological roles. Evid Based Complement Alternat Med 670349:17. doi: 10.1155/2011/670349
Soria-Mercado IE, Villarreal-Gómez LJ, Rivas GG, Sánchez NEA (2012) Bioactive compounds from bacteria associated to marine algae, Chap. 3. In: Sammour RH (ed) Biotechnology—molecular studies and novel applications for improved quality of human life. InTech, Rijeka, ISBN: 978-953-51-0151-2. doi:10.5772/27842
Thornburg CC, Zabriskie TM, McPhail KL (2015) Deep-sea hydrothermal vents: potential hot spots for natural products discovery? J Nat Prod 73(3):489–499. doi:10.1021/np900662k
Valls M, de Lorenzo V (2002) Exploiting the genetic and biochemical capacities of bacteria for the remediation of heavy metal pollution. FEMS Microbiol Rev 26:327–338. doi:10.1016/S0168-6445(02)00114-6
Wang YT, Xue YR, Liu CH (2015) A brief review of bioactive metabolites derived from deep-sea fungi. Mar Drugs 13:4594–4616. doi:10.3390/md13084594
Williamson NR, Fineran PC, Gristwood T, Chawrai SR, Leeper FJ, Salmond GPC (2007) Anticancer and immunosuppressive properties of bacterial prodiginines. Future Microbiol 2:605–618. doi:10.2217/17460913.2.6.605
Yada S, Wang Y, Zou Y, Nagasaki K, Hosokawa K, Osaka I, Arakawa R, Enomoto K (2008) Isolation and characterization of two groups of novel marine bacteria producing violacein. Mar Biotechnol 10:128–132. doi:10.1007/s10126-007-9046-9
Yi H, Chang YH, Oh HW, Bae KS, Chun J (2003) Zooshikella ganghwensis gen. nov. sp. nov. isolated from tidal flat sediments. Int J Syst Evol Microbiol 53:1013–1018. doi:10.1099/ijs.0.02521-0
Zhang L, An R, Wang J, Sun N, Zhang S, Hu J, Kuai J (2005) Exploring novel bioactive compounds from marine microbes. Curr Opin Microbiol 8:276–281. doi:10.1016/j.mib.2005.04.008
Zhu H, Liu J, Qu J, Gao X, Pan T, Cui Z, Zhao X, Lu JR (2013) Stress fermentation strategies for production of hyperthermostable superoxide dismutase from Thermus thermophilus HB27: effects of ions. Extremophiles 17:995–1002. doi:10.1007/s00972-013-0581-1
Acknowledgment
The authors wish to thank Dr. M. V. Deshpande, Emeritus Scientist, Biochemical Division, CSIR-National Chemical Laboratory, Pune (India), for his valuable guidance. The words are insufficient to thank the Dr. V. C. Kalia (Chief Scientist, CSIR-Institute of Genomics and Integrative Biology; Professor, Academy of Scientific and Innovative Research, Delhi University Campus, Delhi (India), for his continuous support. BNR is thankful to the University Grants Commission for the financial support in the form of the postdoctoral fellowship (No. F. PDFSS-2013-14-ST-MAH-4350 – Website).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Rekadwad, B., Khobragade, C. (2017). Marine Polyextremophiles and Their Biotechnological Applications. In: Kalia, V., Kumar, P. (eds) Microbial Applications Vol.1. Springer, Cham. https://doi.org/10.1007/978-3-319-52666-9_15
Download citation
DOI: https://doi.org/10.1007/978-3-319-52666-9_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-52665-2
Online ISBN: 978-3-319-52666-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)