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Hereditary and Familial Lymphedemas

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Lymphedema

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Abstract

Progress in identifying causal mutations has reshaped the way primary lymphedema is managed. Classifying primary lymphedema simply as congenital, praecox, or tarda is no longer adequate. Mutation testing is the way forward, but deep phenotyping is still needed to help discriminate different forms of primary lymphedema for which causal genes are still not known. A proposed algorithm can help with diagnosis. How best to approach those forms of primary lymphedema, which are familial, is presented.

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Authors and Affiliations

  1. Lymphovascular Research Unit, St George’s University of London, London, UK

    Peter S. Mortimer, Kristiana Gordon, Glen Brice & Sahar Mansour

Authors
  1. Peter S. Mortimer
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  2. Kristiana Gordon
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  3. Glen Brice
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  4. Sahar Mansour
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Corresponding author

Correspondence to Peter S. Mortimer .

Editor information

Editors and Affiliations

  1. Center for the Lymphedema and Vascular Malformations, Division of Vascular Surgery, Department of Surgery, George Washington University, Washington, DC, USA

    Byung-Boong Lee

  2. Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, California, USA

    Stanley G. Rockson

  3. La Jolla, California, USA

    John Bergan

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© 2018 Springer International Publishing AG

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Mortimer, P.S., Gordon, K., Brice, G., Mansour, S. (2018). Hereditary and Familial Lymphedemas. In: Lee, BB., Rockson, S., Bergan, J. (eds) Lymphedema. Springer, Cham. https://doi.org/10.1007/978-3-319-52423-8_3

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  • DOI: https://doi.org/10.1007/978-3-319-52423-8_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-52421-4

  • Online ISBN: 978-3-319-52423-8

  • eBook Packages: MedicineMedicine (R0)

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