Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
De Jonghe B, Bastuji-Garin S, Durand MC et al (2007) Respiratory weakness is associated with limb weakness and delayed weaning in critical illness. Crit Care Med 35:2007–2015
Adler D, Dupuis-Lozeron E, Richard JC, Janssens JP, Brochard L (2014) Does inspiratory muscle dysfunction predict readmission after intensive care unit discharge? Am J Respir Crit Care Med 190:347–350
Levine S, Nguyen T, Taylor N et al (2008) Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 358:1327–1335
Jaber S, Petrof BJ, Jung B et al (2011) Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans. Am J Respir Crit Care Med 183:364–371
Hussain SN, Mofarrahi M, Sigala I et al (2010) Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy. Am J Respir Crit Care Med 182:1377–1386
Matecki S, Dridi H, Jung B et al (2016) Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation. Proc Natl Acad Sci U S A 113:9069–9074
Hooijman PE, Beishuizen A, Witt CC et al (2015) Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients. Am J Respir Crit Care Med 191:1126–1138
van Hees HW, Schellekens WJ, Linkels M et al (2011) Plasma from septic shock patients induces loss of muscle protein. Crit Care 15:R233
Demoule A, Jung B, Prodanovic H et al (2013) Diaphragm dysfunction on admission to the intensive care unit. Prevalence, risk factors, and prognostic impact – a prospective study. Am J Respir Crit Care Med 188:213–219
Demoule A, Molinari N, Jung B et al (2016) Patterns of diaphragm function in critically ill patients receiving prolonged mechanical ventilation: a prospective longitudinal study. Ann Intensive Care 6:75
Supinski GS, Westgate P, Callahan LA (2016) Correlation of maximal inspiratory pressure to transdiaphragmatic twitch pressure in intensive care unit patients. Crit Care 20:77
Goligher EC, Fan E, Herridge MS et al (2015) Evolution of diaphragm thickness during mechanical ventilation. Impact of inspiratory effort. Am J Respir Crit Care Med 192:1080–1088
Colombo D, Cammarota G, Alemani M et al (2011) Efficacy of ventilator waveforms observation in detecting patient-ventilator asynchrony. Crit Care Med 39:2452–2457
Doorduin J, van Hees HW, van der Hoeven JG, Heunks LM (2013) Monitoring of the respiratory muscles in the critically ill. Am J Respir Crit Care Med 187:20–27
Heunks LM, Doorduin J, van der Hoeven JG (2015) Monitoring and preventing diaphragm injury. Curr Opin Crit Care 21:34–41
Akoumianaki E, Maggiore SM, Valenza D et al (2014) The application of esophageal pressure measurement in patients with respiratory failure. Am J Respir Crit Care Med 189:520–531
Mauri T, Eronia N, Turrini C et al (2016) Bedside assessment of the effects of positive end-expiratory pressure on lung inflation and recruitment by the helium dilution technique and electrical impedance tomography. Intensive Care Med 42:1576–1587
Bellani G, Mauri T, Coppadoro A et al (2013) Estimation of patient's inspiratory effort from the electrical activity of the diaphragm. Crit Care Med 41:1483–1491
Liu L, Liu S, Xie J et al (2015) Assessment of patient-ventilator breath contribution during neurally adjusted ventilatory assist in patients with acute respiratory failure. Crit Care 19:43
Annane D (2016) What Is the evidence for harm of neuromuscular blockade and corticosteroid use in the intensive care unit? Semin Respir Crit Care Med 37:51–56
Papazian L, Forel JM, Gacouin A et al (2010) Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:107–116
Sassoon CS, Zhu E, Caiozzo VJ (2004) Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 170:626–632
Doorduin J, Sinderby CA, Beck J et al (2015) Assisted ventilation in patients with acute respiratory distress syndrome: Lung-distending pressure and patient-ventilator interaction. Anesthesiology 123:181–190
Pavlovic D, Wendt D (2003) Diaphragm pacing during prolonged mechanical ventilation of the lungs could prevent from respiratory muscle fatigue. Med Hypotheses 60:398–403
Maddocks M, Nolan CM, Man WD et al (2016) Neuromuscular electrical stimulation to improve exercise capacity in patients with severe COPD: a randomised double-blind, placebo-controlled trial. Lancet Respir Med 4:27–36
Zanotti E, Felicetti G, Maini M, Fracchia C (2003) Peripheral muscle strength training in bed-bound patients with COPD receiving mechanical ventilation: effect of electrical stimulation. Chest 124:292–296
Abdellaoui A, Prefaut C, Gouzi F et al (2011) Skeletal muscle effects of electrostimulation after COPD exacerbation: a pilot study. Eur Respir J 38:781–788
Luo YM, Lyall RA, Lou HM, Rafferty GF, Polkey MI, Moxham J (1999) Quantification of the esophageal diaphragm electromyogram with magnetic phrenic nerve stimulation. Am J Respir Crit Care Med 160:1629–1634
Cattapan SE, Laghi F, Tobin MJ (2003) Can diaphragmatic contractility be assessed by airway twitch pressure in mechanically ventilated patients? Thorax 58:58–62
Reynolds SC, Meyyappan R, Thakkar V et al (2016) Mitigation of ventilator-induced diaphragm atrophy by transvenous phrenic nerve stimulation. Am J Respir Crit Care Med Aug 8, Epub ahead of print
Schellekens WJ, van Hees HW, Doorduin J et al (2016) Strategies to optimize respiratory muscle function in ICU patients. Crit Care 20:103
Martin AD, Smith BK, Davenport PD et al (2011) Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial. Crit Care 15:R84
Bissett BM, Leditschke IA, Neeman T, Boots R, Paratz J (2016) Inspiratory muscle training to enhance recovery from mechanical ventilation: a randomised trial. Thorax 71:812–819
Bhasin S, Storer TW, Berman N et al (1996) The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. N Engl J Med 335:1–7
Pan L, Wang M, Xie X, Du C, Guo Y (2014) Effects of anabolic steroids on chronic obstructive pulmonary disease: a meta-analysis of randomised controlled trials. PLoS One 9:e84855
Schols AM, Soeters PB, Mostert R, Pluymers RJ, Wouters EF (1995) Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial. Am J Respir Crit Care Med 152:1268–1274
Takala J, Ruokonen E, Webster NR et al (1999) Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 341:785–792
Farmakis D, Alvarez J, Gal TB et al (2016) Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper. Int J Cardiol 222:303–312
van Hees HW, Dekhuijzen PN, Heunks LM (2009) Levosimendan enhances force generation of diaphragm muscle from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 179:41–47
Doorduin J, Sinderby CA, Beck J et al (2012) The calcium sensitizer levosimendan improves human diaphragm function. Am J Respir Crit Care Med 185:90–95
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Jonkman, A., Jansen, D., Heunks, L.M.A. (2017). Novel Insights in ICU-Acquired Respiratory Muscle Dysfunction: Implications for Clinical Care. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2017. Annual Update in Intensive Care and Emergency Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-51908-1_24
Download citation
DOI: https://doi.org/10.1007/978-3-319-51908-1_24
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-51907-4
Online ISBN: 978-3-319-51908-1
eBook Packages: MedicineMedicine (R0)