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Food Bioactives pp 227–263Cite as

Emerging Technologies of Hydrogels in Bioactive Compounds Delivery

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Abstract

Polyphenols have attracted great interest due to the growing evidence of their beneficial effect on human health. Research on the application of polyphenols has increased especially in functional foods, nutraceutical, and pharmaceutical industries. However, one problem in human health is related to the effectiveness of polyphenols, which depends on preserving the stability, bioactivity, and bioavailability of the bioactive compounds. Additionally, the unpleasant taste of some phenolic compounds limits their use in pharmaceutical application. The encapsulation of polyphenols, instead of free compounds, can effectively help to solve some of the drawbacks. Hydrogels are very interesting biopolymers, emerging as technologies for encapsulation of polyphenols. Hydrogel classification, preparation, characterization, and measurements are reviewed. Several in vitro (preclinical trials) and in vivo studies have demonstrated multiple beneficial effects of polyphenols in prevention or in therapeutics of important pathologies, such as cardiovascular, thrombosis, atherosclerosis, inflammation, cancer, or neurodegenerative diseases. Current research, developments, and trends are also outlined in this chapter.

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Authors and Affiliations

  1. Research Institute for Medicines (IMed.ULisboa), Faculty of Pharmacy, Universidade Lisboa, Av. Gama Pinto, 1649-003, Lisbon, Portugal

    Maria Henriques L. Ribeiro

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  1. Maria Henriques L. Ribeiro
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Correspondence to Maria Henriques L. Ribeiro .

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  1. Deakin University, Waurn Ponds, Victoria, Australia

    Munish Puri

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Ribeiro, M.H.L. (2017). Emerging Technologies of Hydrogels in Bioactive Compounds Delivery. In: Puri, M. (eds) Food Bioactives. Springer, Cham. https://doi.org/10.1007/978-3-319-51639-4_10

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