Skip to main content
SpringerLink
Log in
Book cover

Clinical Cases in Phototherapy pp 107–112Cite as

Enhancing Phototherapy with Topical Agents

  • Chapter
  • First Online:

  • 701 Accesses

Part of the book series: Clinical Cases in Dermatology ((CLIDADE))

Abstract

Various topical agents can be used to augment the effectiveness of phototherapy for psoriasis, especially when the lesions are thick and light cannot penetrate. Topical retinoids (tazoratene) and keratolytics (salicylic acid and lactic acid) can help reduce scale. Coal tar and anthralin, although messy and more difficult to use, can also increase the effectiveness of phototherapy as demonstrated in the Goeckerman regimen and Ingram regimen, respectively.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Lebwohl M. Acitretin in combination with UVB or PUVA. J Am Acad Dermatol. 1999;41(3 Pt 2):S22–4.

    Article  CAS  PubMed  Google Scholar 

  2. Weinstein GD. Tazarotene gel: efficacy and safety in plaque psoriasis. J Am Acad Dermatol. 1997;37(2 Pt 3):S33–8.

    Article  CAS  PubMed  Google Scholar 

  3. Koo JY. Tazarotene in combination with phototherapy. J Am Acad Dermatol. 1998;39(4 Pt 2):S144–8.

    Article  CAS  PubMed  Google Scholar 

  4. Koo JY, Lowe NJ, Lew-Kaya DA, et al. Tazarotene plus UVB phototherapy in the treatment of psoriasis. J Am Acad Dermatol. 2000;43(5 Pt 1):821–8.

    Article  CAS  PubMed  Google Scholar 

  5. Behrens S, Grundmann-Kollmann M, Schiener R, Peter RU, Kerscher M. Combination phototherapy of psoriasis with narrow-band UVB irradiation and topical tazarotene gel. J Am Acad Dermatol. 2000;42(3):493–5.

    Article  CAS  PubMed  Google Scholar 

  6. Krueger GG, Drake LA, Elias PM, et al. The safety and efficacy of tazarotene gel, a topical acetylenic retinoid, in the treatment of psoriasis. Arch Dermatol. 1998;134:57–60.

    Article  CAS  PubMed  Google Scholar 

  7. Lebwohl M, Ast E, Callen JP. et a. Once-daily tazarotene gel versus twice-daily fluocinonide cream in the treatment of plaque psoriasis. J Am Acad Dermatol. 1998;38(5 Pt 1):705–11.

    Article  CAS  PubMed  Google Scholar 

  8. Jacobi A, Mayer A, Augustin M. Keratolytics and emollients and their role in the therapy of psoriasis: a systematic review. Dermatol Ther (Heidelb). 2015;5(1):1–18.

    Article  Google Scholar 

  9. Asztalos ML, Heller MM, Lee ES, Koo J. The impact of emollients on phototherapy: a review. J Am Acad Dermatol. 2013;68(5):817–24.

    Article  CAS  PubMed  Google Scholar 

  10. Menkes A, Stern RS, Arndt KA. Psoriasis treatment with suberythemogenic ultraviolet B radiation and a coal tar extract. J Am Acad Dermatol. 1984;12:21–5.

    Article  Google Scholar 

  11. Sehgal VN, Verma P, Khurana A. Anthralin/dithranol in dermatology. Int J Dermatol. 2014;53(10):e449–60.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Psoriasis and Skin Treatment Center, Department of Dermatology, University of California San Francisco, San Francisco, California, USA

    John Koo & Mio Nakamura

Authors
  1. John Koo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mio Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Koo, J., Nakamura, M. (2017). Enhancing Phototherapy with Topical Agents. In: Clinical Cases in Phototherapy. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-51599-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-51599-1_16

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-51598-4

  • Online ISBN: 978-3-319-51599-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation