Herpes Simplex

  • Andres PintoEmail author


  • A careful history of patients who complain of oral lesions will guide the astute clinician toward a correct differential diagnosis for herpes simplex.

  • Particular attention should be placed to early prodromal symptoms of herpes simplex.

  • Early treatment (within 24–48 h of the prodromal cycle) of suspicious herpes simplex lesions is suggested for the efficacy of systemic treatment.

  • Most clinical trial data is derived from studies on HSV-2 or primary infection cases. Concrete evidence for recurrent herpes labialis or recurrent intraoral herpes is limited.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Oral and Maxillofacial Medicine and Diagnostic SciencesUniversity Hospitals Case Medical Center and Case Western Reserve School of Dental MedicineClevelandUSA

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