Skip to main content

White Blood Cells Detection in Images

  • Chapter
  • First Online:
Evolutionary Computation Techniques: A Comparative Perspective

Part of the book series: Studies in Computational Intelligence ((SCI,volume 686))

Abstract

As a research area, there are several problems in medical imaging that continue unresolved; one of those is the automatic detection of white blood cells (WBC) in smear images. The study of this kind of images has engaged researchers from fields of medicine and computer vision alike. Several studies have been done to try to approximate this cells with circular or ellipsoid forms; once detected, those cells can be further processed by computer vision systems. In this chapter, detection of WBC in smear digitalized images is achieved by using evolutionary algorithms, with an objective function that considers that since WBC can be approximated by an ellipsoid form, an ellipse detector algorithm may be successfully applied in order to recognize them. In that sense, the optimization problem also consider that a candidate solution is a probable ellipse that could adjust a WBC in the image.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. L., Long, L.R., Antani, S., Thoma, G.R. He, “Histology image analysis for carcinoma detection and grading,” Computer Methods and Programs in Biomedicine, 107 (3), pp. 538–556, vol. 107, no. 3, pp. 538–556, 2012.

    Google Scholar 

  2. Til Aach, Thomas M. Deserno, Torsten Kuhlen Ingrid Scholl, “Challenges of medical image processing,” Comput Sci Res Dev, 26, (2011), 5–13, vol. 26, no. 2011, pp. 5–13, 2011.

    Google Scholar 

  3. L. Burtseva, “Why should we use the non-existent? Advantages of application of unconventional computing to processing of noisy medical images,” E-Health and Bioengineering Conference (EHB), vol. 2015, pp. 1–4., 2015.

    Google Scholar 

  4. Sajeena T A and Jereesh A S, “Automated cervical cancer detection through RGVF segmentation and SVM classification,” 2015 International Conference on Computing and Network Communications (CoCoNet), vol. 2015, pp. 663–669, 2015.

    Google Scholar 

  5. H. T. G. and V. V. Nair S. U. Abdulla, “A General Approach for Color Feature Extraction of Microorganisms in Urine Smear Images,” Fifth International Conference on Advances in Computing and Communications (ICACC), vol. 2015, pp. 338–341, 2015.

    Google Scholar 

  6. Andrea Loddo, Lorenzo Putzu Cecilia Di Ruberto, “A Multiple Classifier Learning by Sampling System for White Blood Cells Segmentation,” in Computer Analysis of Images and Patterns.: Springer International Publishing, 2015, vol. 9257, pp. 415–425.

    Google Scholar 

  7. M. Wang and R. Chu, “A novel white blood cell detection method based on boundary support vectors,” Systems, Man and Cybernetics, 2009. SMC 2009. IEEE International Conference on, vol. 2009, no. 1, pp. 2595–2598, 2009.

    Google Scholar 

  8. S.A. Kareem, H. Ariffin, A.A. Zaidan, H.O. Alanazi and B.B. Zaidan H.T. Madhloom, “An Automated White Blood Cell Nucleus Localization and Segmentation using Image Arithmetic and Automatic Threshold,” Journal of Applied Sciences, vol. 10, no. 1, pp. 959–966, 2010.

    Google Scholar 

  9. Jaroonrut, and Pluempitiwiriyawej, Charnchai Prinyakupt, “Segmentation of white blood cells and comparison of cell morphology by linear and naïve Bayes classifiers,” BioMedical Engineering OnLine, vol. 14, no. 1, pp. 1–19, 2015.

    Google Scholar 

  10. P. Zeng, Y. Zhou and C. Olivier J. Wu, “A novel color image segmentation method and its application to white blood cell image analysis,” 8th international Conference on Signal Processing, pp. 1–4, 2006.

    Google Scholar 

  11. F.L. Korris, D. Fu S. Wang, “Applying the improved fuzzy cellular neural network IFCNN to white blood cell detection,” Neurocomputing, vol. 70, no. 2007, pp. 1348–1359, 2007.

    Google Scholar 

  12. NoName, “Circle detection on images based on an evolutionary algorithm that reduces the number of function evaluations,” vol. 100, pp. 139–167, 2016.

    Google Scholar 

  13. M. Nixon H. Muammar, “Approaches to extending the Hough transform,” Proc. Int. Conf. on Acoustics, Speech and Signal Processing ICASSP-89, vol. 3, no. 1989, pp. 1556–1559, 1989.

    Google Scholar 

  14. D. Kerbyson T. Atherton, “Using phase to represent radius in the coherent circle Hough transform,” IEE Colloquium on the Hough Transform, IEEE, vol. 1993, pp. 1–4.

    Google Scholar 

  15. R. Bolles, M. Fischer, “Random sample consensus: A paradigm to model fitting with applications to image analysis and automated cartography,” CACM, vol. 24, no. 6, pp. 381–395, 1981.

    Google Scholar 

  16. O. Yaron, N. Kiryati D. Shaked, “Deriving stopping rules for the probabilistic Hough transform by sequential analysis,” Comput. Vis. Image. Und., vol. 63, no. 1996, pp. 512–526, 1996.

    Google Scholar 

  17. E. Oja, P. Kultanen L. Xu, “A new curve detection method: Randomized Hough transform (RHT),” Pattern Recogn. Lett., vol. 11, no. 5, pp. 331–338, 1990.

    Google Scholar 

  18. L. Koczy J. Han, “Fuzzy Hough transform,” Proc. 2nd Int. Conf. on Fuzzy Systems, vol. 2, no. 1993, pp. 803–808, 1993.

    Google Scholar 

  19. V., Garcia-Capulin, C. H., Perez-Garcia, A. and Sanchez-Yanez, R. E. Ayala-Ramirez, “Circle detection on images using genetic algorithms,” Pattern Recognition Letters, vol. 27, no. 2006, pp. 652–657, 2006.

    Google Scholar 

  20. Martinez P Lutton E, “A genetic algorithm for the detection of 2D geometric primitives in images,” Proceedings of the 12th international conference on pattern recognition, vol. 1, no. 1994, pp. 526–528, October 1994.

    Google Scholar 

  21. Nawwaf Kharma, Peter Grogono Jie Yao, “A multi-population genetic algorithm for robust and fast ellipse detection,” Pattern Anal Applic, vol. 8, no. 2005, pp. 149–162, 2005.

    Google Scholar 

  22. Yanhui Guo, Yingtao Zhang H.D. Cheng, “A novel Hough transform based on eliminating particle swarm optimization and its applications,” Pattern Recognition, vol. 42, no. 9, pp. 1959–1969.

    Google Scholar 

  23. M. Rangoussi G. Karkavitsas, “Object localization in medical images using genetic algorithms,” World Academy of Science, Eng. and Tec., vol. 2, no. 2005, pp. 6–9, 2005.

    Google Scholar 

  24. Price K. Storn R, “Differential evolution - a simple and efficient adaptive scheme for global optimization over continuous spaces,” International Computer Science Institute, Berkley, Technical Rep. TR-95-012, 1995.

    Google Scholar 

  25. Munawar S. Babu B, “Differential evolution strategies for optimal design of shell-and-tube heat exchangers,” Chem Eng Sci., vol. 62, no. 14, pp. 3720–3739, 2007.

    Google Scholar 

  26. Kinghorn B, Archer A. Mayer D, “Differential evolution – an easy and efficient evolutionary algorithm for model optimization,” Agr Syst, vol. 83, no. 2005, pp. 315–328, 2005.

    Google Scholar 

  27. Mary Raja Slochanal S, Padhy N. Kannan S, “Application and comparison of metaheuristic techniques to generation expansion planning problem,” IEEE Trans Power Syst, vol. 20, no. 1, pp. 466–475, 2003.

    Google Scholar 

  28. Chang C, Su C. Chiou J, “Variable scaling hybrid differential evolution for solving network reconfiguration of distribution systems,” IEEE Trans Power Syst, vol. 20, no. 2, pp. 668–674, 2005.

    Google Scholar 

  29. D. Zaldivar, M. Pérez-Cisneros E. Cuevas, “A novel multi-threshold segmentation approach based on differential evolution optimization,” Expert Systems with Applications, vol. 37, no. 2010, pp. 5265–5271, 2010.

    Google Scholar 

  30. J.E. Bresenham, “A Linear Algorithm for Incremental Digital Display of Circular Arcs,” Communications of the ACM, vol. 20, no. 1977, pp. 100–106, 1977.

    Google Scholar 

  31. J R. Van Aken, “Efficient ellipse-drawing algorithm,” IEEE Comp, Graphics applic., vol. 4, no. 9, pp. 24–35, 2005.

    Google Scholar 

  32. M. Ferraro, P. Napoletano G. Boccignone, “Diffused expectation maximisation for image segmentation,” Electron Letters, vol. 40, pp. 1107–1108, 2004.

    Google Scholar 

  33. P. Napoletano, V. Caggiano, M. Ferraro G. Boccignonea, “A multi-resolution diffused expectation-maximization algorithm for medical image segmentation,” Computers in Biology and Medicine, vol. 37, no. 2007, pp. 83–96, 2007.

    Google Scholar 

  34. (2012) DEM: Diffused expectation maximization function for image segmentation. [Online]. http://www.mathworks.com/matlabcentral/fileexchange/37197-dem-diffused-expectation-maximisation-for-image-segmentation

  35. R.C. Gonzalez and R.E.Woods, Digital Image Processing, 1992nd ed., MA Reading, Ed.: Addison Wesley, 1992.

    Google Scholar 

  36. F. Huang L. Wang, “Parameter analysis based on stochastic model for differential evolution algorithm,” Applied Mathematics and Computation, vol. 217, no. 7, pp. 3263–3273, 2010.

    Google Scholar 

  37. R. Wagner M. Tapiovaara, “SNR and noise measurements for medical imaging: I. A practical approach based on statistical decision theory,” Physics in Medicine and Biology, vol. 38, no. 1, pp. 71–92, 1993.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Erik Cuevas .

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Cuevas, E., Osuna, V., Oliva, D. (2017). White Blood Cells Detection in Images. In: Evolutionary Computation Techniques: A Comparative Perspective. Studies in Computational Intelligence, vol 686. Springer, Cham. https://doi.org/10.1007/978-3-319-51109-2_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-51109-2_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-51108-5

  • Online ISBN: 978-3-319-51109-2

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics