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Communication of Drug Loaded Nanogels with Cancer Cell Receptors for Targeted Delivery

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Modeling, Methodologies and Tools for Molecular and Nano-scale Communications

Part of the book series: Modeling and Optimization in Science and Technologies ((MOST,volume 9))

Abstract

The human body is a massive nanoscale molecular communications network composed of billions of interacting cells Drug delivery is an important application of molecular communication. Nanogels are aqueous dispersions of nanoscale size formed by cross-linking of hydrophilic polymers, capable of retaining large amounts of water yet remaining insoluble and maintaining a three-dimensional structure. Nanogel structure enables easy attachment of vector groups for effective communication with cells to reach the desired targeted site. This chapter highlights communication of drug loaded nanogels for targeting cancer through receptors. The chapter critically discusses receptors like- integrin αvβ3, EphA2, folate, Hyaluronan and monoclonal antibody for communication with nanogels.

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Acknowledgements

Dr. K.S. Yadav thanks AICTE, New Delhi, for the award of Research Promotion Scheme project (Ref No. 8023/RID/RPS-71/POLICY III(PVT)/2011–12).

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Authors and Affiliations

  1. Department of Pharmaceutics, Rajeev Gandhi College of Pharmacy, Bhopal-42, Madhya Pradesh, India

    Govind Soni & Khushwant S. Yadav

Authors
  1. Govind Soni
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  2. Khushwant S. Yadav
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Correspondence to Khushwant S. Yadav .

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Editors and Affiliations

  1. Department of Computer Science, University of Massachusetts, Boston, Massachusetts, USA

    Junichi Suzuki

  2. Graduate School of Biological Sciences, Osaka University, Osaka, Japan

    Tadashi Nakano

  3. 57006D Applied Science Building, Pennsylvania State University, State College, Pennsylvania, USA

    Michael John Moore

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Soni, G., Yadav, K.S. (2017). Communication of Drug Loaded Nanogels with Cancer Cell Receptors for Targeted Delivery. In: Suzuki, J., Nakano, T., Moore, M. (eds) Modeling, Methodologies and Tools for Molecular and Nano-scale Communications. Modeling and Optimization in Science and Technologies, vol 9. Springer, Cham. https://doi.org/10.1007/978-3-319-50688-3_21

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  • DOI: https://doi.org/10.1007/978-3-319-50688-3_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-50686-9

  • Online ISBN: 978-3-319-50688-3

  • eBook Packages: EngineeringEngineering (R0)

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