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Endoluminal Bariatric Procedures

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NOTES and Endoluminal Surgery

Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Obesity is a disease that is growing in burden. It is estimated that over 1.4 billion people worldwide suffer from obesity, and 68% of Americans are considered overweight or obese. While bariatric surgery has also increased in popularity over the last two decades, the morbidity of these procedures has led investigators to develop less invasive therapies that may cause weight loss and resolution of comorbid conditions associated with obesity. There are two intragastric balloons on the market in the USA, which have been widely available in Europe and other countries, and three more remain under investigation but should be available soon. These balloons are typically placed endoscopically and are removed after a duration of months. Other novel technologies to treat obesity that are under investigation include endoscopic suturing devices to create anatomic simulations of bariatric procedures, endoluminal sleeves that create malabsorptive states, aspiration therapy to reduce caloric intake, duodenal mucosal resurfacing to induce malabsorption, and endoscopic magnetic anastomotic devices to create intestinal bypasses. These new devices may eventually become part of a growing toolbox for surgeons and endoscopists to offer therapy to morbidly obese patients in a much less invasive manner than bariatric surgery, although more data are needed.

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Abbreviations

ASGE/ASMBS:

American Society of Gastrointestinal Endoscopy/American Society for Metabolic and Bariatric Surgery

BIB:

Bioenterics Intragastric Balloon, now known as Orbera™

BMI:

Body mass index

CC:

Completed cases

CVD:

Cardiovascular disease

DJBS:

Duodenojejunal bypass sleeve

DMR:

Duodenal mucosal resurfacing

EBT:

Endoscopic bariatric therapy

EBW:

Excess BMI weight loss

ESG:

Endoscopic sleeve gastroplasty

EWL:

Excess weight loss

FDA:

Food and Drug Administration

HDL:

High-density lipoprotein

IGB:

Intragastric balloon

IOP:

Incisionless operating platform

POSE:

Primary obesity surgery endoluminal

ITT:

Intent to treat

LDL:

Low-density lipoprotein

NHANES:

National Health and Nutrition Examination Survey

NIH:

National Institutes of Health

PEG:

Percutaneous endoscopic gastrostomy

TWL:

Total weight loss

WHO:

World Health Organization

References

  1. Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197–209.

    Article  PubMed  Google Scholar 

  2. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999–2008. JAMA. 2010;303(3):235–41.

    Article  CAS  PubMed  Google Scholar 

  3. Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010. JAMA. 2012;307(5):491–7.

    Article  PubMed  Google Scholar 

  4. Cawley J, Meyerhoefer C. The medical care costs of obesity: an instrumental variables approach. J Health Econ. 2012;31(1):219–30.

    Article  PubMed  Google Scholar 

  5. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002;288(14):1723–7.

    Article  PubMed  Google Scholar 

  6. Finkelstein EA, Trogdon JG, Cohen JW, Dietz W. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood). 2009;28(5):w822–31.

    Article  Google Scholar 

  7. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8):806–14.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000;894:i–xii, 1–253.

    Google Scholar 

  9. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9945):766–81.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Swinburn BA, Sacks G, Hall KD, McPherson K, Finegood DT, Moodie ML, et al. The global obesity pandemic: shaped by global drivers and local environments. Lancet. 2011;378(9793):804–14.

    Article  PubMed  Google Scholar 

  11. McTigue K, Larson JC, Valoski A, Burke G, Kotchen J, Lewis CE, et al. Mortality and cardiac and vascular outcomes in extremely obese women. JAMA. 2006;296(1):79–86.

    Article  CAS  PubMed  Google Scholar 

  12. Nguyen NT, Magno CP, Lane KT, Hinojosa MW, Lane JS. Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey, 1999 to 2004. J Am Coll Surg. 2008;207(6):928–34.

    Article  PubMed  Google Scholar 

  13. Bhaskaran K, Douglas I, Forbes H, dos-Santos-Silva I, Leon DA, Smeeth L. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Lancet. 2014;384(9945):755–65.

    Google Scholar 

  14. Gortmaker SL, Must A, Perrin JM, Sobol AM, Dietz WH. Social and economic consequences of overweight in adolescence and young adulthood. N Engl J Med. 1993;329(14):1008–12.

    Article  CAS  PubMed  Google Scholar 

  15. Lau DC, Teoh H. Benefits of modest weight loss on the management of type 2 diabetes mellitus. Can J Diabetes. 2013;37(2):128–34.

    Article  PubMed  Google Scholar 

  16. Soleymani T, Daniel S, Garvey WT. Weight maintenance: challenges, tools and strategies for primary care physicians. Obes Rev. 2016;17(1):81–93.

    Article  CAS  PubMed  Google Scholar 

  17. Mathus-Vliegen EM. Endoscopic treatment: the past, the present and the future. Best Pract Res Clin Gastroenterol. 2014;28(4):685–702.

    Article  CAS  PubMed  Google Scholar 

  18. Clinical Guidelines on the Identification. Evaluation, and treatment of overweight and obesity in adults—the evidence report. National Institutes of Health. Obes Res. 1998;6(Suppl 2):51S–209S.

    Google Scholar 

  19. Swinburn BA, Caterson I, Seidell JC, James WP. Diet, nutrition and the prevention of excess weight gain and obesity. Public Health Nutr. 2004;7(1A):123–46.

    CAS  PubMed  Google Scholar 

  20. Wadden TA, Webb VL, Moran CH, Bailer BA. Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy. Circulation. 2012;125(9):1157–70.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Gregg EW, Chen H, Wagenknecht LE, Clark JM, Delahanty LM, Bantle J, et al. Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA. 2012;308(23):2489–96.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Diabetes Prevention Program Research G, Knowler WC, Fowler SE, Hamman RF, Christophi CA, Hoffman HJ, et al. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet. 2009;374(9702):1677–86.

    Google Scholar 

  23. Look ARG. Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. Obesity (Silver Spring). 2014;22(1):5–13.

    Article  Google Scholar 

  24. Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA. 2014;311(1):74–86.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Sjostrom L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683–93.

    Article  PubMed  Google Scholar 

  26. Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.

    Article  PubMed  Google Scholar 

  27. Bariatric surgery lowers all-cause mortality in the morbidly obese. J Fam Pract. 2007;56(11):893.

    Google Scholar 

  28. Gloy VL, Briel M, Bhatt DL, Kashyap SR, Schauer PR, Mingrone G, et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;347:f5934.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Colquitt JL, Pickett K, Loveman E, Frampton GK. Surgery for weight loss in adults. Cochrane Database Syst Rev. 2014;8:CD003641.

    Google Scholar 

  30. Morino M, Toppino M, Forestieri P, Angrisani L, Allaix ME, Scopinaro N. Mortality after bariatric surgery: analysis of 13,871 morbidly obese patients from a national registry. Ann Surg. 2007;246(6):1002–7 (discussion 7-9).

    Google Scholar 

  31. Flum DR, Dellinger EP. Impact of gastric bypass operation on survival: a population-based analysis. J Am Coll Surg. 2004;199(4):543–51.

    Article  PubMed  Google Scholar 

  32. Chang SH, Stoll CR, Song J, Varela JE, Eagon CJ, Colditz GA. The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003–2012. JAMA Surg. 2014;149(3):275–87.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg. 2013;23(4):427–36.

    Article  PubMed  Google Scholar 

  34. Thompson CC. Bariatric endoscopy. Thompson CC, Ryan, M.B., editors. New York: Springer; 2013.

    Google Scholar 

  35. Kumar N. Endoscopic therapy for weight loss: gastroplasty, duodenal sleeves, intragastric balloons, and aspiration. World J Gastrointest Endosc. 2015;7(9):847–59.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Cote GA, Edmundowicz SA. Emerging technology: endoluminal treatment of obesity. Gastrointest Endosc. 2009;70(5):991–9.

    Article  PubMed  Google Scholar 

  37. Stimac D, Majanovic SK. The position of endoscopic procedures in the treatment of obesity. Curr Clin Pharmacol. 2013;8(3):238–46.

    Article  PubMed  Google Scholar 

  38. Majumder S, Birk J. A review of the current status of endoluminal therapy as a primary approach to obesity management. Surg Endosc. 2013;27(7):2305–11.

    Article  PubMed  Google Scholar 

  39. van Hout G, van Heck G. Bariatric psychology, psychological aspects of weight loss surgery. Obes Facts. 2009;2(1):10–5.

    Article  PubMed  Google Scholar 

  40. Prospective Studies C, Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet. 2009;373(9669):1083–96.

    Google Scholar 

  41. van de Laar A, de Caluwe L, Dillemans B. Relative outcome measures for bariatric surgery. Evidence against excess weight loss and excess body mass index loss from a series of laparoscopic Roux-en-Y gastric bypass patients. Obes Surg. 2011;21(6):763–7.

    Google Scholar 

  42. Dixon JB, McPhail T, O’Brien PE. Minimal reporting requirements for weight loss: current methods not ideal. Obes Surg. 2005;15(7):1034–9.

    Article  PubMed  Google Scholar 

  43. Dallal RM, Quebbemann BB, Hunt LH, Braitman LE. Analysis of weight loss after bariatric surgery using mixed-effects linear modeling. Obes Surg. 2009;19(6):732–7.

    Article  PubMed  Google Scholar 

  44. Therapy AATFoEB, Ginsberg GG, Chand B, Cote GA, Dallal RM, Edmundowicz SA, et al. A pathway to endoscopic bariatric therapies. Gastrointest Endosc. 2011;74(5):943–53.

    Google Scholar 

  45. Genco A, Maselli R, Frangella F, Cipriano M, Paone E, Meuti V, et al. Effect of consecutive intragastric balloon (BIB(R)) plus diet versus single BIB(R) plus diet on eating disorders not otherwise specified (EDNOS) in obese patients. Obes Surg. 2013;23(12):2075–9.

    Article  PubMed  Google Scholar 

  46. Abu Dayyeh BK, Kumar N, Edmundowicz SA, Jonnalagadda S, Larsen M, Sullivan S, et al. ASGE Bariatric Endoscopy Task Force systematic review and meta-analysis assessing the ASGE PIVI thresholds for adopting endoscopic bariatric therapies. Gastrointest Endosc. 2015;82(3):425–38e5.

    Google Scholar 

  47. Genco A, Maselli R, Frangella F, Cipriano M, Forestieri P, Delle Piane D, et al. Intragastric balloon for obesity treatment: results of a multicentric evaluation for balloons left in place for more than 6 months. Surg Endosc. 2015;29(8):2339–43.

    Article  PubMed  Google Scholar 

  48. Lopez-Nava G, Galvao M, Bautista-Castano I, Fernandez-Corbelle JP, Trell M. Endoscopic sleeve gastroplasty with 1-year follow-up: factors predictive of success. Endosc Int Open. 2016;4(2):E222–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Genco A, Bruni T, Doldi SB, Forestieri P, Marino M, Busetto L, et al. BioEnterics intragastric balloon: the Italian experience with 2515 patients. Obes Surg. 2005;15(8):1161–4.

    Article  CAS  PubMed  Google Scholar 

  50. Gaur S, Levy S, Mathus-Vliegen L, Chuttani R. Balancing risk and reward: a critical review of the intragastric balloon for weight loss. Gastrointest Endosc. 2015;81(6):1330–6.

    Article  PubMed  Google Scholar 

  51. Nieben OG, Harboe H. Intragastric balloon as an artificial bezoar for treatment of obesity. Lancet. 1982;1(8265):198–9.

    Article  CAS  PubMed  Google Scholar 

  52. Dumonceau JM. Evidence-based review of the bioenterics intragastric balloon for weight loss. Obes Surg. 2008;18(12):1611–7.

    Article  PubMed  Google Scholar 

  53. Fernandes M, Atallah AN, Soares BG, Humberto S, Guimaraes S, Matos D, et al. Intragastric balloon for obesity. Cochrane Database Syst Rev. 2007(1):CD004931.

    Google Scholar 

  54. Gleysteen JJ. A history of intragastric balloons. Surg Obes Relat Dis. 2015.

    Google Scholar 

  55. Ponce J, Woodman G, Swain J, Wilson E, English W, Ikramuddin S, et al. The REDUCE pivotal trial: a prospective, randomized controlled pivotal trial of a dual intragastric balloon for the treatment of obesity. Surg Obes Relat Dis. 2015;11(4):874–81.

    Article  PubMed  Google Scholar 

  56. Imaz I, Martinez-Cervell C, Garcia-Alvarez EE, Sendra-Gutierrez JM, Gonzalez-Enriquez J. Safety and effectiveness of the intragastric balloon for obesity. A meta-analysis. Obes Surg. 2008;18(7):841–6.

    Article  PubMed  Google Scholar 

  57. Abu Dayyeh BK, Edmundowicz SA, Jonnalagadda S, Kumar N, Larsen M, Sullivan S, et al. Endoscopic bariatric therapies. Gastrointest Endosc. 2015;81(5):1073–86.

    Google Scholar 

  58. Dastis NS, Francois E, Deviere J, Hittelet A, Ilah Mehdi A, Barea M, et al. Intragastric balloon for weight loss: results in 100 individuals followed for at least 2.5 years. Endoscopy. 2009;41(7):575–80.

    Article  PubMed  Google Scholar 

  59. Genco A, Lopez-Nava G, Wahlen C, Maselli R, Cipriano M, Sanchez MM, et al. Multi-centre European experience with intragastric balloon in overweight populations: 13 years of experience. Obes Surg. 2013;23(4):515–21.

    Article  PubMed  Google Scholar 

  60. Kotzampassi K, Grosomanidis V, Papakostas P, Penna S, Eleftheriadis E. 500 intragastric balloons: what happens 5 years thereafter? Obes Surg. 2012;22(6):896–903.

    Article  PubMed  Google Scholar 

  61. Lopez-Nava G, Rubio MA, Prados S, Pastor G, Cruz MR, Companioni E, et al. BioEnterics(R) intragastric balloon (BIB(R)). Single ambulatory center Spanish experience with 714 consecutive patients treated with one or two consecutive balloons. Obes Surg. 2011;21(1):5–9.

    Article  PubMed  Google Scholar 

  62. Genco A, Cipriano M, Bacci V, Maselli R, Paone E, Lorenzo M, et al. Intragastric balloon followed by diet vs intragastric balloon followed by another balloon: a prospective study on 100 patients. Obes Surg. 2010;20(11):1496–500.

    Article  PubMed  Google Scholar 

  63. Dumonceau JM, Francois E, Hittelet A, Mehdi AI, Barea M, Deviere J. Single vs repeated treatment with the intragastric balloon: a 5-year weight loss study. Obes Surg. 2010;20(6):692–7.

    Article  PubMed  Google Scholar 

  64. Mion F, Ibrahim M, Marjoux S, Ponchon T, Dugardeyn S, Roman S, et al. Swallowable Obalon(R) gastric balloons as an aid for weight loss: a pilot feasibility study. Obes Surg. 2013;23(5):730–3.

    Article  PubMed  Google Scholar 

  65. Machytka E, Chuttani R, Bojkova M, Kupka T, Buzga M, Stecco K, et al. Elipse, a procedureless gastric balloon for weight loss: a proof-of-concept pilot study. Obes Surg. 2016;26(3):512–6.

    Article  PubMed  Google Scholar 

  66. Machytka E, Klvana P, Kornbluth A, Peikin S, Mathus-Vliegen LE, Gostout C, et al. Adjustable intragastric balloons: a 12-month pilot trial in endoscopic weight loss management. Obes Surg. 2011;21(10):1499–507.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Brooks J, Srivastava ED, Mathus-Vliegen EM. One-year adjustable intragastric balloons: results in 73 consecutive patients in the U.K. Obes Surg. 2014;24(5):813–9.

    Article  CAS  PubMed  Google Scholar 

  68. Genco A, Dellepiane D, Baglio G, Cappelletti F, Frangella F, Maselli R, et al. Adjustable intragastric balloon vs non-adjustable intragastric balloon: case-control study on complications, tolerance, and efficacy. Obes Surg. 2013;23(7):953–8.

    Article  PubMed  Google Scholar 

  69. Sharaiha RZ, Kedia P, Kumta N, DeFilippis EM, Gaidhane M, Shukla A, et al. Initial experience with endoscopic sleeve gastroplasty: technical success and reproducibility in the bariatric population. Endoscopy. 2015;47(2):164–6.

    PubMed  Google Scholar 

  70. Abu Dayyeh BK, Acosta A, Camilleri M, Mundi MS, Rajan E, Topazian MD, et al. Endoscopic sleeve gastroplasty alters gastric physiology and induces loss of body weight in obese individuals. Clin Gastroenterol Hepatol. 2015.

    Google Scholar 

  71. Espinos JC, Turro R, Mata A, Cruz M, da Costa M, Villa V, et al. Early experience with the Incisionless Operating Platform (IOP) for the treatment of obesity: the primary obesity surgery endolumenal (POSE) procedure. Obes Surg. 2013;23(9):1375–83.

    Article  CAS  PubMed  Google Scholar 

  72. Bradley D, Magkos F, Klein S. Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology. 2012;143(4):897–912.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  73. Rubino F, Forgione A, Cummings DE, Vix M, Gnuli D, Mingrone G, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006;244(5):741–9.

    Article  PubMed  PubMed Central  Google Scholar 

  74. Klein S, Fabbrini E, Patterson BW, Polonsky KS, Schiavon CA, Correa JL, et al. Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes. Obesity (Silver Spring). 2012;20(6):1266–72.

    Article  CAS  Google Scholar 

  75. Tarnoff M, Rodriguez L, Escalona A, Ramos A, Neto M, Alamo M, et al. Open label, prospective, randomized controlled trial of an endoscopic duodenal-jejunal bypass sleeve versus low calorie diet for pre-operative weight loss in bariatric surgery. Surg Endosc. 2009;23(3):650–6.

    Article  CAS  PubMed  Google Scholar 

  76. Gersin KS, Rothstein RI, Rosenthal RJ, Stefanidis D, Deal SE, Kuwada TS, et al. Open-label, sham-controlled trial of an endoscopic duodenojejunal bypass liner for preoperative weight loss in bariatric surgery candidates. Gastrointest Endosc. 2010;71(6):976–82.

    Article  PubMed  Google Scholar 

  77. Schouten R, Rijs CS, Bouvy ND, Hameeteman W, Koek GH, Janssen IM, et al. A multicenter, randomized efficacy study of the endobarrier gastrointestinal liner for presurgical weight loss prior to bariatric surgery. Ann Surg. 2010;251(2):236–43.

    Article  PubMed  Google Scholar 

  78. de Moura EG, Martins BC, Lopes GS, Orso IR, de Oliveira SL, Galvao Neto MP, et al. Metabolic improvements in obese type 2 diabetes subjects implanted for 1 year with an endoscopically deployed duodenal-jejunal bypass liner. Diabetes Technol Ther. 2012;14(2):183–9.

    Article  PubMed  Google Scholar 

  79. Escalona A, Pimentel F, Sharp A, Becerra P, Slako M, Turiel D, et al. Weight loss and metabolic improvement in morbidly obese subjects implanted for 1 year with an endoscopic duodenal-jejunal bypass liner. Ann Surg. 2012;255(6):1080–5.

    Article  PubMed  Google Scholar 

  80. de Jonge C, Rensen SS, Verdam FJ, Vincent RP, Bloom SR, Buurman WA, et al. Endoscopic duodenal-jejunal bypass liner rapidly improves type 2 diabetes. Obes Surg. 2013;23(9):1354–60.

    Article  PubMed  Google Scholar 

  81. Koehestanie P, de Jonge C, Berends FJ, Janssen IM, Bouvy ND, Greve JW. The effect of the endoscopic duodenal-jejunal bypass liner on obesity and type 2 diabetes mellitus, a multicenter randomized controlled trial. Ann Surg. 2014;260(6):984–92.

    Article  PubMed  Google Scholar 

  82. Sullivan S, Stein R, Jonnalagadda S, Mullady D, Edmundowicz S. Aspiration therapy leads to weight loss in obese subjects: a pilot study. Gastroenterology. 2013;145(6):1245–52e1-5.

    Google Scholar 

  83. Nauck MA, Meier JJ. The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions. Lancet Diabetes Endocrinol. 2016.

    Google Scholar 

  84. Knop FK, Vilsboll T, Hojberg PV, Larsen S, Madsbad S, Volund A, et al. Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state? Diabetes. 2007;56(8):1951–9.

    Article  CAS  PubMed  Google Scholar 

  85. Ryou M, Cantillon-Murphy P, Azagury D, Shaikh SN, Ha G, Greenwalt I, et al. Smart Self-Assembling MagnetS for ENdoscopy (SAMSEN) for transoral endoscopic creation of immediate gastrojejunostomy (with video). Gastrointest Endosc. 2011;73(2):353–9.

    Article  PubMed  Google Scholar 

  86. van Avesaat M, Troost FJ, Ripken D, Hendriks HF, Masclee AA. Ileal brake activation: macronutrient-specific effects on eating behavior? Int J Obes (Lond). 2015;39(2):235–43.

    Article  Google Scholar 

  87. Ryou M, Agoston AT, Thompson CC. Endoscopic intestinal bypass creation by using self-assembling magnets in a porcine model. Gastrointest Endosc. 2016;83(4):821–5.

    Article  PubMed  Google Scholar 

  88. Alfredo G, Roberta M, Massimiliano C, Michele L, Nicola B, Adriano R. Long-term multiple intragastric balloon treatment—a new strategy to treat morbid obese patients refusing surgery: prospective 6-year follow-up study. Surg Obes Relat Dis. 2014;10(2):307–11.

    Article  PubMed  Google Scholar 

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Disclosures

Jonah Cohen has no disclosures to report related to this work.

Ram Chuttani is a senior medical advisor to Allurion Technologies.

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Authors and Affiliations

  1. Department of Medicine and Division of Gastroenterology, Center for Advanced Endoscopy, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Stoneman 458, Boston, MA, USA

    Jonah Cohen & Ram Chuttani

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  1. Jonah Cohen
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  2. Ram Chuttani
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Correspondence to Ram Chuttani .

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Editors and Affiliations

  1. Department of Surgery, University of Massachusetts / Baystate Medical Center, Springfield, Massachusetts, USA

    John R. Romanelli

  2. Division of Gastroenterology, University of Massachusetts / Baystate Medical Center, Springfield, Massachusetts, USA

    David J. Desilets

  3. Lowell Surgical Associates , North Chelmsford, Massachusetts, USA

    David B. Earle

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Cohen, J., Chuttani, R. (2017). Endoluminal Bariatric Procedures. In: Romanelli, J., Desilets, D., Earle, D. (eds) NOTES and Endoluminal Surgery. Clinical Gastroenterology. Springer, Cham. https://doi.org/10.1007/978-3-319-50610-4_10

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