Abstract
The field of nutrition originated from the discovery of vitamins, a group of organic essential compounds. Vitamins are not synthesized by the body in amounts adequate to meet normal physiological functioning and therefore minute amounts obtained through diet are essential for maintenance, growth, development, and reproduction. Insufficient intake of micronutrients, both vitamins and minerals, leads to specific deficiency syndromes.
Traditionally, vitamins have been classified based on their solubilities. The fat-soluble vitamins (A, D, E, K) are absorbed passively, transported with dietary lipid, and tend to be stored in the liver and in body fat but may be excreted with the feces. The water-soluble vitamins (C and the eight B vitamins) are absorbed by passive or active mechanisms, transported by carriers, are not stored in appreciable amounts in the body, and are excreted in the urine. Table 1 provides an overview of the vitamins according to their functions, food sources, recommended levels of intake to support health, stability, as well as deficiency and toxicity symptoms.
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References
Stahl W, Ale-Agha N, Polidori MC. Non-antioxidant properties of carotenoids. Biol Chem. 2002;383:553–8.
Brown CC, Noelle RJ. Seeing through the dark: new insights into the immune regulatory functions of vitamin A. Eur J Immunol. 2015;45:1287–95.
Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J Leukoc Biol. 2002;71:16–32.
Bettendorff L. A non-cofactor role of thiamine derivatives in excitable cells? Arch Physiol Biochem. 1996;104:745–51.
Kirkland JB. Niacin status impacts chromatin structure. J Nutr. 2009;139:2397–401.
Lavigne PM, Karas RH. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression. J Am Coll Cardiol. 2013;61:440–6.
Gdynia HJ, Müller T, Sperfeld AD, et al. Severe sensorimotor neuropathy after intake of highest dosages of vitamin B6. Neuromuscul Disord. 2008;18:156–8.
Stabler SP. Clinical folate deficiency. In: Bailey LB, editor. Folate in health and disease. 2nd ed. Boca Raton: CRC Press, Taylor & Francis Group; 2010. p. 409–28.
Institute of Medicine. Dietary Reference Intakes: applications in dietary assessment. Washington: National Academies Press; 2000.
Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013;CD000980.
Scragg R. Vitamin D and public health: an overview of recent research on common diseases and mortality in adulthood. Public Health Nutr. 2011;14:1515–32.
Sigmund CD. Regulation of renin expression and blood pressure by vitamin D(3). J Clin Invest. 2002;110:155–6.
Brigelius-Flohé R. Adverse effects of vitamin E by induction of drug metabolism. Genes Nutr. 2007;2:249–56.
Ferland G. Vitamin K and brain function. Semin Thromb Hemost. 2013;39:849–55.
Johnson MA. Influence of vitamin K on anticoagulant therapy depends on vitamin K status and the source and chemical forms of vitamin K. Nutr Rev. 2005;63:91–100.
Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ. 2014;348:g1903.
Theodoratou E, Tzoulaki I, Zgaga L, Ioannidis JP. Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ. 2014;348:g2035.
Cahill LE, Fontaine-Bisson B, El-Sohemy A. Functional genetic variants of glutathione S-transferase protect against serum ascorbic acid deficiency. Am J Clin Nutr. 2009;90:1411–7.
Tsang BL, Devine OJ, Cordero AM, et al. Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C >T polymorphism and blood folate concentrations: a systematic review and meta-analysis of trials and observational studies. Am J Clin Nutr. 2015;101:1286–94.
Suggested Further Reading
Institute of Medicine. Dietary Reference Intakes: the essential guide to nutrient requirements. Washington, DC: National Academies Press; 2006.
Office of Dietary Supplements. National Institutes of Health (NIH). This site provides information on vitamins (and minerals), the safe use of supplements, and the research available on the treatment of health problems and disease with various supplements. http://ods.od.nih.gov
U.S. Department of Agriculture’s Food and Nutrition Information Center. This site provides information on food composition and topics related to vitamins and minerals. https://fnic.nal.usda.gov
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Davison, K.M. (2017). Vitamins: The Essentials. In: Temple, N., Wilson, T., Bray, G. (eds) Nutrition Guide for Physicians and Related Healthcare Professionals. Nutrition and Health. Humana Press, Cham. https://doi.org/10.1007/978-3-319-49929-1_25
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DOI: https://doi.org/10.1007/978-3-319-49929-1_25
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