Skip to main content

Management with Nonsteroidal Anti-inflammatory Agents

  • Chapter
  • First Online:
Scleritis

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

  • 609 Accesses

Abstract

Scleritis is a complex, destructive ocular inflammation, which may be progressive and vision threatening. A treatment challenge to practicing ophthalmologists, patients with scleritis require individualized care based on clinical response, disease severity, and consideration of the overall patient experience. The goal of therapy for scleritis is simple: achievement of a durable, lasting remission devoid of all forms of corticosteroid therapy. This, in the opinion of the authors, is the only potential avenue by which a patient with scleritis can reach a permanent disease-free state. The purpose of this chapter is to introduce and review the medical management of scleritis, with a focus on one variant of first-line therapy, nonsteroidal anti-inflammatory drugs (NSAIDs). A working knowledge of management of patients with scleritis via NSAID therapy is absolutely essential for all practicing ophthalmologists.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kim SJ, Flach AJ, Jampol LM. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol. 2010;55:2.

    Article  Google Scholar 

  2. Jabs DA, Mudun A, Dunn JP, Marsh MJ. Episcleritis and scleritis: clinical features and treatment resul. Am J Ophthalmol. 2000;130:4.

    Google Scholar 

  3. Sainz de la Maza M, Foster CS, Jabbur NS. Scleritis associated with systemic vasculitic diseases. Ophthalmology. 1995;102:4.

    Article  Google Scholar 

  4. Rosenbaum JT, Robertson Jr JE. Recognition of posterior scleritis and its treatment with indomethacin. Retina. 1993;13:1.

    Article  Google Scholar 

  5. Watson PG, Hayreh SS. Scleritis and episcleritis. Br J Ophthalmol. 1976;60:163–91.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Sims J. Scleritis: presentations, disease associations and management. Postgrad Med J. 2012;88:713–8.

    Article  PubMed  Google Scholar 

  7. Wieringa WG, Wieringa JE, ten Dam-van Loon NH, Los LI. Visual outcome, treatment results, and prognostic factors in patients with scleritis. Ophthalmology. 2013;120:2.

    Article  Google Scholar 

  8. Sainz de la Maza M, Molina N, Gonzalez-Gonzalez LA, Doctor PP, Tauber J, Foster CS. Scleritis therapy. Ophthalmology. 2012;119:1.

    Article  Google Scholar 

  9. Wakefield D, Di Girolamo N, Thurau S, Wildner G, McCluskey P. Scleritis: immunopathogenesis and molecular basis for therapy. Prog Retin Eye Res. 2013;35:44–62.

    Article  CAS  PubMed  Google Scholar 

  10. Beardsley RM, Suhler EB, Rosenbaum JT, Lin P. Pharmacotherapy of scleritis: current paradigms and future directions. Expert Opin Pharmacother. 2013;14:4.

    Article  Google Scholar 

  11. Bauer AM, Fiehn C, Becker MD. Celecoxib, a selective inhibitor of cyclooxygenase 2 for therapy of diffuse anterior scleritis. Am J Ophthalmol. 2005;139:6.

    Article  Google Scholar 

  12. Tuft SJ, Watson PG. Progression of scleral disease. Ophthalmology. 1991;98:467–71.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Stephen Foster MD, FACS, FACR .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Metzinger, J.L., Foster, C.S. (2017). Management with Nonsteroidal Anti-inflammatory Agents. In: Pavesio, C. (eds) Scleritis. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-49915-4_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-49915-4_7

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-49913-0

  • Online ISBN: 978-3-319-49915-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics