Abstract
Scleritis is a complex, destructive ocular inflammation, which may be progressive and vision threatening. A treatment challenge to practicing ophthalmologists, patients with scleritis require individualized care based on clinical response, disease severity, and consideration of the overall patient experience. The goal of therapy for scleritis is simple: achievement of a durable, lasting remission devoid of all forms of corticosteroid therapy. This, in the opinion of the authors, is the only potential avenue by which a patient with scleritis can reach a permanent disease-free state. The purpose of this chapter is to introduce and review the medical management of scleritis, with a focus on one variant of first-line therapy, nonsteroidal anti-inflammatory drugs (NSAIDs). A working knowledge of management of patients with scleritis via NSAID therapy is absolutely essential for all practicing ophthalmologists.
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References
Kim SJ, Flach AJ, Jampol LM. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol. 2010;55:2.
Jabs DA, Mudun A, Dunn JP, Marsh MJ. Episcleritis and scleritis: clinical features and treatment resul. Am J Ophthalmol. 2000;130:4.
Sainz de la Maza M, Foster CS, Jabbur NS. Scleritis associated with systemic vasculitic diseases. Ophthalmology. 1995;102:4.
Rosenbaum JT, Robertson Jr JE. Recognition of posterior scleritis and its treatment with indomethacin. Retina. 1993;13:1.
Watson PG, Hayreh SS. Scleritis and episcleritis. Br J Ophthalmol. 1976;60:163–91.
Sims J. Scleritis: presentations, disease associations and management. Postgrad Med J. 2012;88:713–8.
Wieringa WG, Wieringa JE, ten Dam-van Loon NH, Los LI. Visual outcome, treatment results, and prognostic factors in patients with scleritis. Ophthalmology. 2013;120:2.
Sainz de la Maza M, Molina N, Gonzalez-Gonzalez LA, Doctor PP, Tauber J, Foster CS. Scleritis therapy. Ophthalmology. 2012;119:1.
Wakefield D, Di Girolamo N, Thurau S, Wildner G, McCluskey P. Scleritis: immunopathogenesis and molecular basis for therapy. Prog Retin Eye Res. 2013;35:44–62.
Beardsley RM, Suhler EB, Rosenbaum JT, Lin P. Pharmacotherapy of scleritis: current paradigms and future directions. Expert Opin Pharmacother. 2013;14:4.
Bauer AM, Fiehn C, Becker MD. Celecoxib, a selective inhibitor of cyclooxygenase 2 for therapy of diffuse anterior scleritis. Am J Ophthalmol. 2005;139:6.
Tuft SJ, Watson PG. Progression of scleral disease. Ophthalmology. 1991;98:467–71.
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Metzinger, J.L., Foster, C.S. (2017). Management with Nonsteroidal Anti-inflammatory Agents. In: Pavesio, C. (eds) Scleritis. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-49915-4_7
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DOI: https://doi.org/10.1007/978-3-319-49915-4_7
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