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Fibrous Proteins: Structures and Mechanisms pp 491–526Cite as

Recombinant Structural Proteins and Their Use in Future Materials

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Part of the book series: Subcellular Biochemistry ((SCBI,volume 82))

Abstract

Recombinant proteins are polymers that offer the materials engineer absolute control over chain length and composition: key attributes required for design of advanced polymeric materials. Through this control, these polymers can be encoded to contain information that enables them to respond as the environment changes. However, despite their promise, protein-based materials are under-represented in materials science. In this chapter we investigate why this is and describe recent efforts to address this. We discuss constraints limiting rational design of structural proteins for advanced materials; advantages and disadvantages of different recombinant expression platforms; and, methods to fabricate proteins into solid-state materials. Finally, we describe the silk proteins used in our laboratory as templates for information-containing polymers.

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Authors and Affiliations

  1. CSIRO, Black Mountain, 2601, Canberra, ACT, Australia

    Tara D. Sutherland & Trevor D. Rapson

  2. CSIRO, Waurn Ponds, 3216, Geelong, VIC, Australia

    Mickey G. Huson & Jeffrey S. Church

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  1. Tara D. Sutherland
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  2. Trevor D. Rapson
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  3. Mickey G. Huson
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  4. Jeffrey S. Church
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Correspondence to Tara D. Sutherland .

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  1. Institute of Fundamental Sciences and Riddet Institute, Massey University, Palmerston North, New Zealand

    David A.D. Parry

  2. Muscle Contraction Group, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom

    John M. Squire

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Sutherland, T.D., Rapson, T.D., Huson, M.G., Church, J.S. (2017). Recombinant Structural Proteins and Their Use in Future Materials. In: Parry, D., Squire, J. (eds) Fibrous Proteins: Structures and Mechanisms. Subcellular Biochemistry, vol 82. Springer, Cham. https://doi.org/10.1007/978-3-319-49674-0_15

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