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Severe Iodine Deficiency

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Abstract

Severe iodine deficiency is defined as a goiter prevalence greater than 30 % and/or a median urinary iodine concentration (UIC) of less than 20 μg/L in a given population or defined geographical area. The adaptive processes of the thyroid gland may be unable to compensate for this degree of iodine deficiency, leading to manifestations which include endemic goiter, hypothyroidism, obstetric complications, intellectual impairment, and cretinism. However, the manifestations of severe iodine deficiency have decreased globally primarily due to widespread coverage with adequately iodized salt.

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Abbreviations

IDA:

Iron deficiency anemia

IDD:

Iodine deficiency disorders

IGN:

Iodine Global Network

PAHO:

Pan American Health Organization

SF:

Serum ferritin

T3:

Triiodothyronine

TGR:

Total goiter rate

T4:

Thyroxine

TSH:

Thyroid stimulation hormone

UIC:

Urinary iodine concentration

WHO:

World Health Organization

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Authors and Affiliations

  1. Faculty of Medicina, Peruvian University Cayetano Heredia, Iodine Global Network (IGN), Av. Paseo de la República 3691, Ofic. 401-A, San Isidro, Lima 27, Peru

    Eduardo A. Pretell MD

  2. Centre for Community Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, Ansari Nagar, New Delhi, 110029, India

    Chandrakant Pandav MBBS, MD, MSc

Authors
  1. Eduardo A. Pretell MD
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  2. Chandrakant Pandav MBBS, MD, MSc
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Regional Co-ordinator South Asia Iodine Global Network

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Correspondence to Eduardo A. Pretell MD .

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Editors and Affiliations

  1. Boston University School of Medicine, Boston, Massachusetts, USA

    Elizabeth N. Pearce

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Pretell, E.A., Pandav, C., Regional Co-ordinator South Asia Iodine Global Network. (2017). Severe Iodine Deficiency. In: Pearce, E. (eds) Iodine Deficiency Disorders and Their Elimination. Springer, Cham. https://doi.org/10.1007/978-3-319-49505-7_4

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