Skip to main content

Nonpenetrating Glaucoma Surgery (Deep Sclerectomy, Viscocanaloplasty, and Canaloplasty)

  • Chapter
  • First Online:
Managing Complications in Glaucoma Surgery

Abstract

Performing nonpenetrating glaucoma procedures (NPGS) requires a high level of skill. The proposed advantages of NPGS have to be considered in context of the long learning curve and the complications. Inadequate dissection of the filtration membrane, the trabeculo-Descemet’s membrane (TDM) is not uncommon and may result in filtration failure. Intraoperative perforations of the TDM make the procedure similar to a trabeculectomy with the attendant risks. Complications after a routine NPGS procedure are rare and self-limiting. Early hypotony after deep sclerectomy (DS), a conjunctival bleb-dependent NPGS procedure should not be considered a complication. Viscocanaloplasty and canaloplasty (VCT), nonbleb dependent NPGS procedures, often have transient hyphema in the immediate postoperative period due to Schlemm’s canal manipulation. DS procedures have bleb-related complications similar to trabeculectomy. Adjunctive use of mitomycin C may increase the risk of bleb-related infections and hypotony. Detachment of the Descemet’s membrane is an uncommon complication s and may result in failure of the procedure. Laser goniopuncture (LGP) is often performed after DS and can reestablish filtration in a significant majority of eyes. The sudden lowering of IOP after LGP may result in choroidal detachments and suprachoroidal hemorrhage. LGP also increases the risk of iris incarceration and occasionally acute, symptomatic IOP elevation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Al Obeidan SA. Incidence, efficacy and safety of YAG laser goniopuncture following nonpenetrating deep sclerectomy at a university hospital in Riyadh, Saudi Arabia. Saudi J Ophthalmol. 2015;29:95–102.

    Article  PubMed  Google Scholar 

  • Alnahrawy O, Blumenstock G, Ziemssen F, Szurman P, Leitritz MA, Dimopoulos S, Voykov B. Exit strategies in canaloplasty: intraoperative conversion into 180-degree trabeculotomy or 360-degree trabeculotomy in cases of unsuccessful catheterisation of Schlemm’s canal: influence of degree of canal cleavage. Graefes Arch Clin Exp Ophthalmol. 2015;253(5):779–84. doi: 10.1007/s00417-015-2955-9. Epub 2015 Feb 18.

  • Alp MN, Yarangumeli A, Koz OG, Kural G. Nd:YAG laser goniopuncture in viscocanalostomy: penetration in non-penetrating glaucoma surgery. Int Ophthalmol. 2010;30(3):245–52. doi:10.1007/s10792-009-9312-0.

    Article  PubMed  Google Scholar 

  • Anand N, Atherley C. Deep sclerectomy augmented with mitomycin C. Eye (Lond). 2005;19(4):442–50. doi:10.1038/sj.eye.6701403.

    Article  CAS  Google Scholar 

  • Anand N, Bong C. Deep sclerectomy with bevacizumab and mitomycin C: a comparative study. J Glaucoma. 2015;24(1):25–31. doi:10.1097/IJG.0b013e3182883c0c.

  • Anand N, Pilling R. Nd:YAG laser goniopuncture after deep sclerectomy: outcomes. Acta Ophthalmol. 2010;88(1):110–5. doi:10.1111/j.1755-3768.2008.01494.x.

    Article  PubMed  Google Scholar 

  • Anand N, Kumar A, Gupta A. Primary phakic deep sclerectomy augmented with mitomycin C: long-term outcomes. J Glaucoma. 2011;20(1):21–7. doi:10.1097/IJG.0b013e3181ccb926.

    Article  PubMed  Google Scholar 

  • Ayyala RS, Chaudhry AL, Okogbaa CB, et al. Comparison of surgical outcomes between canaloplasty and trabeculectomy at 12 months’ follow-up. Ophthalmology. 2011;118:2427–33.

    Article  PubMed  Google Scholar 

  • Barnebey HS. Canaloplasty with intraoperative low dosage mitomycin C: a retrospective case series. J Glaucoma. 2013;22(3):201–4. doi:10.1097/IJG.0b013e31824083fb.

    Article  PubMed  Google Scholar 

  • Carassa RG, Bettin P, Fiori M, Brancato R. Viscocanalostomy versus trabeculectomy in white adults affected by open-angle glaucoma: a 2-year randomized, controlled trial. Ophthalmology. 2003;110(5):882–7. doi:10.1016/S0161-6420(03)00081-2.

    Article  PubMed  Google Scholar 

  • Cillino S, Di Pace F, Casuccio A, et al. Deep sclerectomy versus punch trabeculectomy: effect of low-dosage mitomycin C. Ophthalmologica. 2005;219:281–6.

    Article  PubMed  Google Scholar 

  • Cillino S, Di Pace F, Casuccio A, et al. Deep sclerectomy versus trabeculectomy with low-dosage mitomycin C: four-year follow-up. Ophthalmologica. 2008;222:81–7.

    Article  CAS  PubMed  Google Scholar 

  • Eldaly MA, Bunce C, Elsheikha OZ, Wormald R. Non-penetrating filtration surgery versus trabeculectomy for open-angle glaucoma. Cochrane Database Syst Rev. 2014;2:CD007059. doi:10.1002/14651858.CD007059.pub2.

    Google Scholar 

  • Grieshaber MC, Fraenkl S, Schoetzau A, Flammer J, Orgül S. Circumferential viscocanalostomy and suture canal distension (canaloplasty) for whites with open-angle glaucoma. J Glaucoma. 2011;20(5):298–302. doi:10.1097/IJG.0b013e3181e3d46e.

    Article  PubMed  Google Scholar 

  • Grieshaber MC, Schoetzau A, Flammer J. Orgül SPostoperative microhyphema as a positive prognostic indicator in canaloplasty. Acta Ophthalmol. 2013;91(2):151–6. doi:10.1111/j.1755-3768.2011.02293.x. Epub 2011 Dec 9

    Article  CAS  PubMed  Google Scholar 

  • The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS Investigators. Am J Ophthalmol. 2000;130(4):429–40.

    Google Scholar 

  • Jaramillo A, Foreman J, Ayyala RS. Descemet membrane detachment after canaloplasty: incidence and management. J Glaucoma. 2014;23(6):351–4. doi:10.1097/IJG.0b013e318279ca7f.

    Article  CAS  PubMed  Google Scholar 

  • Karlen ME, Sanchez E, Schnyder CC, Sickenberg M, Mermoud A. Deep sclerectomy with collagen implant: medium term results. Br J Ophthalmol. 1999;83(1):6–11.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kobayashi H, Kobayashi K, Okinami S. A comparison of the intraocular pressure-lowering effect and safety of viscocanalostomy and trabeculectomy with mitomycin C in bilateral open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol. 2003;241(5):359–66. doi:10.1007/s00417-003-0652-6.

    Article  CAS  PubMed  Google Scholar 

  • Koukkoulli A, Musa F, Anand N. Long-term outcomes of needle revision of failing deep sclerectomy blebs. Graefes Arch Clin Exp Ophthalmol. 2015;253(1):99–106. doi:10.1007/s00417-014-2810-4.

    Article  PubMed  Google Scholar 

  • Kozobolis VP, Christodoulakis EV, Tzanakis N, Zacharopoulos I, Pallikaris IG. Primary deep sclerectomy versus primary deep sclerectomy with the use of mitomycin C in primary open-angle glaucoma. J Glaucoma. 2002;11(4):287–93.

    Article  PubMed  Google Scholar 

  • Krasnov MM. Externalization of Schlemm’s canal (sinusotomy) in glaucoma. Br J Ophthalmol. 1968;52(2):157–61.

    Google Scholar 

  • Lewis RA, von Wolff K, Tetz M, Koerber N, Kearney JR, Shingleton BJ, Samuelson TW. Canaloplasty: three-year results of circumferential viscodilation and tensioning of Schlemm canal using a microcatheter to treat open-angle glaucoma. J Cataract Refract Surg. 2011;37(4):682–90. doi:10.1016/j.jcrs.2010.10.055.

    Article  PubMed  Google Scholar 

  • Luke C, Dietlein TS, Jacobi PC, Konen W, Krieglstein GK. A prospective randomized trial of viscocanalostomy versus trabeculectomy in open-angle glaucoma: a 1-year follow-up study. J Glaucoma. 2002;11(4):294–9.

    Article  PubMed  Google Scholar 

  • Mendrinos E, Mermoud A, Shaarawy T. Nonpenetrating glaucoma surgery. Surv Ophthalmol. 2008;53:592–630.

    Article  PubMed  Google Scholar 

  • Mermoud A, Karlen ME, Schnyder CC, Sickenberg M, Chiou AG, Hediguer SE, Sanchez E. Nd:Yag goniopuncture after deep sclerectomy with collagen implant. Ophthalmic Surg Lasers. 1999;30(2):120–5.

    CAS  PubMed  Google Scholar 

  • O’Brart DP, Shiew M, Edmunds B. A randomised, prospective study comparing trabeculectomy with viscocanalostomy with adjunctive antimetabolite usage for the management of open angle glaucoma uncontrolled by medical therapy. Br J Ophthalmol. 2004;88(8):1012–7. doi:10.1136/bjo.2003.037432.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ravinet E, Tritten JJ, Roy S, Gianoli F, Wolfensberger T, Schnyder C, Mermoud A. Descemet membrane detachment after nonpenetrating filtering surgery. J Glaucoma. 2002;11(3):244–52.

    Article  CAS  PubMed  Google Scholar 

  • Rulli E, Biagioli E, Riva I, et al. Efficacy and safety of trabeculectomy vs nonpenetrating surgical procedures: a systematic review and meta-analysis. JAMA Ophthalmol. 2013;131:1573–82.

    Article  CAS  PubMed  Google Scholar 

  • Russo V, Scott IU, Stella A, Balducci F, Cosma A, Barone A, Delle Noci N. Nonpenetrating deep sclerectomy with reticulated hyaluronic acid implant versus punch trabeculectomy: a prospective clinical trial. Eur J Ophthalmol. 2008;18(5):751–7.

    CAS  PubMed  Google Scholar 

  • Sanchez E, Schnyder CC, Mermoud A. Comparative results of deep sclerectomy transformed to trabeculectomy and classical trabeculectomy. Klin Monatsbl Augenheilkd. 1997;210(5):261–4. doi:10.1055/s-2008-1035050.

    Article  CAS  PubMed  Google Scholar 

  • Shaarawy T, Flammer J, Smits G, Mermoud A. Low first postoperative day intraocular pressure as a positive prognostic indicator in deep sclerectomy. Br J Ophthalmol. 2004;88(5):658–61.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stegmann RC. Visco-canalostomy: a new surgical technique for open angle glaucoma. An Inst Barraquer. 1995;25:229–32.

    Google Scholar 

  • Stegmann R, Pienaar A, Miller D. Viscocanalostomy for open-angle glaucoma in black African patients. J Cataract Refract Surg. 1999;25(3):316–22.

    Article  CAS  PubMed  Google Scholar 

  • Sponsel WE1, Groth SL. Mitomycin-augmented non-penetrating deep sclerectomy: preoperative gonioscopy and postoperative perimetric, tonometric and medication trends. Br J Ophthalmol. 2013;97(3):357–61. doi: 10.1136/bjophthalmol-2012-301886. Epub 2012 Nov 2.

    Google Scholar 

  • Sunaric-Megevand G, Leuenberger PM. Results of viscocanalostomy for primary open-angle glaucoma. Am J Ophthalmol. 2001;132(2):221–8.

    Article  CAS  PubMed  Google Scholar 

  • Tamm ER, Carassa RG, Albert DM, Gabelt BT, Patel S, Rasmussen CA, Kaufman PL. Viscocanalostomy in rhesus monkeys. Arch Ophthalmol. 2004 Dec;122(12):1826–38.

    Article  PubMed  Google Scholar 

  • Vuori ML. Complications of Neodymium:YAG laser goniopuncture after deep sclerectomy. Acta Ophthalmol Scand. 2003;81(6):573–6.

    Article  PubMed  Google Scholar 

  • Wallin OJ, Montan PG. Blebitis after deep sclerectomy. Eye (Lond). 2007;21(2):258–60. doi:10.1038/sj.eye.6702494.

    Article  CAS  Google Scholar 

  • Yalvac IS, Sahin M, Eksioglu U, Midillioglu IK, Aslan BS, Duman S. Primary viscocanalostomy versus trabeculectomy for primary open-angle glaucoma: three-year prospective randomized clinical trial. J Cataract Refract Surg. 2004;30(10):2050–7. doi:10.1016/j.jcrs.2004.02.073.

    Article  PubMed  Google Scholar 

  • Yarangümeli A, Köz OG, Alp MN, Elhan AH, Kural G. Viscocanalostomy with mitomycin-C: a preliminary study. Eur J Ophthalmol. 2005;15(2):202–8.

    PubMed  Google Scholar 

  • Zimmerman TJ, Kooner KS, Ford VJ, Olander KW, Mandlekorn RM, Rawlings EF, Leader BJ, Koskan AJ. Trabeculectomy vs. nonpenetrating trabeculectomy: a retrospective study of two procedures in phakic patients with glaucoma. Ophthalmic Surg. 1984;15(9):734–40.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nitin Anand .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Cheng, J., Hu, K., Anand, N. (2017). Nonpenetrating Glaucoma Surgery (Deep Sclerectomy, Viscocanaloplasty, and Canaloplasty). In: Carbonaro, F., Lim, K. (eds) Managing Complications in Glaucoma Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-49416-6_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-49416-6_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-49414-2

  • Online ISBN: 978-3-319-49416-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics