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Packaging of the Implant

  • Gürkan YılmazEmail author
  • Catherine Dehollain
Chapter
  • 979 Downloads
Part of the Analog Circuits and Signal Processing book series (ACSP)

Abstract

Any kind of passive or active device which is to be implanted inside the body must satisfy certain biocompatibility and biosafety requirements and standards. It is worth noting that not harming the patient (primum non nocere) is one of the fundamentals of the medicine and medical sciences. These requirements have been established in years in order to prevent inflicting any damage to the human body. More explicitly, the implant may contain a toxic material which causes a direct damage to the tissues, or the body may refuse the implant even if the implant itself is not toxic, which causes an indirect damage. This refusal is called as foreign body reaction [1], and as a result, the immune system attacks the implant which results in an inflammation or swelling in return. In such cases, the implant should be removed immediately. Therefore, a set of preliminary experiments have to be conducted in order to get an approval. This chapter introduces the regulations and how these regulations are addressed within the frame of this work including a polymer-based packaging, and its modeling in terms of hermetical sealing is presented. Proposed packaging has been tested only for in vitro conditions and requires a detailed characterization to fulfill the requirements of biocompatibility before in vivo experiments.

Keywords

Parylene-C Hermetical sealing Biocompatibility Polymer packaging Diffusion barrier 

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.EPFL RFIC Research GroupLausanneSwitzerland

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