Skip to main content

Clinical Aspects of Movement Disorders: Effects on Walking and Posture

  • Chapter
  • First Online:
Locomotion and Posture in Older Adults

Abstract

Movement disorders are a group of syndromes which includes parkinsonism, chorea, dystonia, myoclonus, tremor, and tics. Many of the diseases of this group manifest disturbances of gait and posture along with other abnormalities. Parkinsonism is characterized by rest tremor, muscular rigidity, bradykinesia, flexed posture of the trunk, and loss of postural reflexes. Parkinson’s disease (PD) is the most prevalent of the diseases of this group and patients usually manifest problems of gait and posture in late phases. On the other hand, atypical parkinsonism diseases (multiple-system atrophy, progressive supranuclear palsy, dementia with Lewy bodies, and corticobasal ganglionic degeneration) manifest gait problems and falls very early and are much more incapacitating than PD. Vascular parkinsonism manifests itself with lower limb rigidity and bradykinesia and affects gait very early. Huntington’s disease is a genetic disorder characterized by behavioral and cognitive disturbances associated with chorea, dystonia, and loss of equilibrium. Sometimes, especially in subjects with the juvenile form of Huntington’s disease, it may manifest with a very severe parkinsonism.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fahn S, Jankovic J. Principle and practice of movement disorders. Philadelphia: Churchill Livingstone; 2007. p. 652.

    Google Scholar 

  2. Campbell WW. DeJong’s. The neurologic examination. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2013.

    Google Scholar 

  3. Jellinger KA. Neuropathological spectrum of synucleinopathies. Mov Disord. 2003;18 suppl 6:S2–12.

    Article  PubMed  Google Scholar 

  4. Kalia LV, Lang AE. Parkinson’s disease. Lancet. 2015;386:896–912.

    Article  CAS  PubMed  Google Scholar 

  5. Jankovic J, McDermott M, Carter J, et al. Variable expression of Parkinson’s disease: a baseline analysis of the DATATOP cohort. Neurology. 1990;41:1529–34.

    Article  Google Scholar 

  6. Connolly BS, Lang AE. Pharmacological treatment of Parkinson’s disease. A review. JAMA. 2014;311:1670–83.

    Article  PubMed  Google Scholar 

  7. Wagle Shukla A, Okun MS. Surgical treatment of Parkinson’s disease: patients, targets, devices, and approaches. Neurotherapeutics. 2014;11:47–59.

    Article  PubMed  Google Scholar 

  8. Fanciulli A, Wenning GK. Multiple-system atrophy. N Engl J Med. 2015;372:249–63.

    Article  PubMed  Google Scholar 

  9. Golbe LI. Progressive supranuclear palsy. Semin Neurol. 2014;34:151–9.

    Article  PubMed  Google Scholar 

  10. Walker Z, Possin KL, Boeve BF, Aarsland D. Lewy body dementias. Lancet. 2015;386:1683–94.

    Article  PubMed  Google Scholar 

  11. Benítez-Rivero S, Lama MJ, Huertas-Fernández I, et al. Clinical features and neuropsychological profile in vascular parkinsonism. J Neurol Sci. 2014;345:193–7.

    Article  PubMed  Google Scholar 

  12. Vale TC, Caramelli P, Cardoso F. Clinicoradiological comparison between vascular parkinsonism and Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2015;86(5):547–53.

    Article  PubMed  Google Scholar 

  13. Wang HC, Hsu JL, Leemans A. Diffusion tensor imaging of vascular parkinsonism: structural changes in cerebral white matter and the association with clinical severity. Arch Neurol. 2012;69:1340–8.

    Article  PubMed  Google Scholar 

  14. FitzGerald PM, Jankovic J. Lower body parkinsonism: evidence for vascular etiology. Mov Disord. 1989;4:249–60.

    Article  CAS  PubMed  Google Scholar 

  15. Constantinescu R, Richard I, Kurlan R. Levodopa responsiveness in disorders with parkinsonism: a review of the literature. Mov Disord. 2007;22:2141–8.

    Article  PubMed  Google Scholar 

  16. Wheeler VC, Persichetti F, McNeil SM, et al. Factors associated with HD CAG repeat instability in Huntington disease. J Med Genet. 2007;44:695–701.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Tabrizi SJ, Langbehn DR, Leavitt BR, TRACK-HD Investigators, et al. Biological and clinical manifestations of Huntington’s disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol. 2009;8:791–801.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Cardoso F. Huntington disease and other choreas. Neurol Clin. 2009;27:719–36.

    Article  PubMed  Google Scholar 

  19. Andrew SE, Goldberg YP, Kremer B, Telenius H, et al. The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington’s disease. Nat Genet. 1993;4:398–403.

    Article  CAS  PubMed  Google Scholar 

  20. Morreale MK. Huntington’s disease: looking beyond the movement disorder. Adv Psychosom Med. 2015;34:135–42.

    Article  PubMed  Google Scholar 

  21. Bonelli RM, Hoffman P. A systematic review of the treatment studies in Huntington’s disease since 1990. Expert Opin Pharmacother. 2007;8:141–53.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Henrique Ballalai Ferraz .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Ferraz, H.B., Saba, R.A. (2017). Clinical Aspects of Movement Disorders: Effects on Walking and Posture. In: Barbieri, F., Vitório, R. (eds) Locomotion and Posture in Older Adults. Springer, Cham. https://doi.org/10.1007/978-3-319-48980-3_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-48980-3_2

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-48979-7

  • Online ISBN: 978-3-319-48980-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics