Abstract
Although the neuropilins (Nrps), neuropilin-1 (Nrp1) and its homologue neuropilin-2 (Nrp2), were originally identified as key molecules involved in the development of neurons, it has recently become clear that they also play important roles in the immune system. The function of Nrp1 has been well characterized, mainly in T cells, including regulatory T (Treg) cells, as well as in dendritic cells (DCs), whereas the immunological function of Nrp2 is less clearly understood. In this chapter, we discuss the identification of Nrp1 and its roles in immune systems.
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Nojima, S., Kumanogoh, A. (2017). The Roles of Neuropilins in the Immune System. In: Neufeld, G., Kessler, O. (eds) The Neuropilins: Role and Function in Health and Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-48824-0_9
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DOI: https://doi.org/10.1007/978-3-319-48824-0_9
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