Skip to main content

Early Detection of Hypoglycemia Events Based on Biometric Sensors Prototyped on FPGAs

  • Conference paper
  • First Online:
Ubiquitous Computing and Ambient Intelligence (UCAmI 2016)

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 10069))

Abstract

Diabetes is a chronic disease that requires continuous medical care and patient self-monitoring processes. The control of the glucose level in blood is a task that the patient needs to perform to prevent hypoglycemia episodes. Early detection of hypoglycemia is a very important element for preventing multi-organ failure. The incorporation of other biomedical parameters monitoring, combined with glucose levels can help to early detect and prevent those episodes. At this respect, several e-health platforms have been developed for monitoring and processing vital signals related to diabetes events. In this paper we evaluate a couple of these platforms and we introduce an algorithm to analyze the data of glucose, in order to anticipate the moment of an hypoglycemia episode. The proposed algorithm contemplates the information of several biomedical sensors, and it is based on the analysis of the gradient of the glucose curve, producing an estimation of the expected time to achieve a given threshold. Besides, the proposed algorithm allows to analyze the correlations of the monitored multi-signals information with diabetes related events. The algorithm was developed to be implemented on an FPGA-based SoC and was evaluated by simulation. The results obtained are very promising and can be scalable to further signals processing.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Annual Report 2012: International Diabetes Federation (2012). http://www.idf.org

  2. Cichosz, S.L., Frystyk, J., Hejlesen, O.K., Lise, T., Jesper, F.: A novel algorithm for prediction and detection of hypoglycemia based on continuous glucose monitoring and heart rate variability in patients with typpe 1 diabetes. J. Diab. Sci. Technol. 8(4), 731–737 (2014)

    Google Scholar 

  3. Halvorson, M., Carpenter, S., Kaiserman, K., Kaufman, F.R.: A pilot trial in pediatrics with the sensor-augmented pump: combining real-time continuous glucose monitoring with the insulin pump. J. Pediatr. 150(1), 103–105 (2007)

    Google Scholar 

  4. Guillod, L., Comte-Perret, S., Monbaron, D., Gaillard, R.C., Ruiz, J.: Nocturnal hypoglycaemias in type 1 diabetic patients: what can we learn with continuous glucose monitoring? Diabetes Metab. 5(33), 360–365 (2007)

    Article  Google Scholar 

  5. Mann, S.: Wearable Computing as Means for Personal Empowerment. IEEE Computer Society Press, Fairfax (1998)

    Google Scholar 

  6. Nguyen, L.L., Su, S., Nguyen, H.T.: Identification of hypoglycemia and hyperglycemia in typpe 1 diabetic patients using ecg parameters. In: 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2716–2719, August 2012

    Google Scholar 

  7. Olansky, L., Kennedy, L.: Finger-stick glucose monitoring. Diabetes Care 33(4), 948–949 (2010). http://dx.doi.org/10.2337/dc10-0077

    Google Scholar 

  8. Rakay, R., Visnovsky, M., Galajdova, A., Simsik, D.: Testing properties of e-health system based on arduino. J. Autom. Control 3(3), 122–126 (2015)

    Google Scholar 

  9. Romero-Aragon, J.C., Sanchez, E.N., Alanis, A.Y.: Glucose level regulation for diabetes mellitus typpe 1 patients using fpga neural inverse optimal control. In: 2014 IEEE Symposium on Computational Intelligence in Control and Automation (CICA), pp. 1–7, December 2014

    Google Scholar 

  10. da Silva, H.P., Guerreiro, J., Loureno, A., Fred, A., Martins, R.: Bitalino: a novel hardware framework for physiological computing. In: Proceedings of the International Conference on Physiological Computing Systems, pp. 246–253 (2014)

    Google Scholar 

  11. Tomasello, A.: Incidencia de Hipoglucemias en DM2 mayores de 60 años medidas a través de monitoreo glucémico continuo y su relación con estilo de vida y tratamiento de Diabetes. Ph.D. thesis, Fundación H.A. Barceló (2014)

    Google Scholar 

  12. Vashist, S.K.: Continuous glucose monitoring systems: a review. Diagnostics 3(4), 385–412 (2013). http://www.mdpi.com/2075-4418/3/4/385

    Google Scholar 

Download references

Acknowledgments

This work has been funded by the Programme for Research and Innovation of University of Castilla-La Mancha, co-financed by the European Social Fund (Resolution of 25 August 2014) and by the Spanish Ministry of Economy and Competitiveness under project REBECCA (TEC2014-58036-C4-1-R) and the Regional Government of Castilla-La Mancha under project SAND (PEII_2014_046_P).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Soledad Escolar .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this paper

Cite this paper

Escolar, S., Abaldea, M.J., Dondo, J.D., Rincón, F., López, J.C. (2016). Early Detection of Hypoglycemia Events Based on Biometric Sensors Prototyped on FPGAs. In: García, C., Caballero-Gil, P., Burmester, M., Quesada-Arencibia, A. (eds) Ubiquitous Computing and Ambient Intelligence. UCAmI 2016. Lecture Notes in Computer Science(), vol 10069. Springer, Cham. https://doi.org/10.1007/978-3-319-48746-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-48746-5_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-48745-8

  • Online ISBN: 978-3-319-48746-5

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics