Abstract
The industrialization of a wearable, mechatronic, biomedical device for blood ultrafiltration would represent an important step toward the achievement of tailored and improved care for kidney disease and congestive heart failure patients. In this article, the conceptual design of a novel and portable device is proposed. The necessary components are identified, and the most suitable technologies for pumps, sensors and control systems are selected, taking into account the basic requirement of minimizing the size and weight of the device in order to make it actually portable and wearable. The selection has also been driven by the results of a thorough risk analysis from a clinical point of view. Most components have been considered as disposables in order to ensure aseptic conditions and easy restoring operations for the device, which is believed to be essential to promote the use of wearable devices for blood purification in clinical practice.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Kim JC et al (2011) A wearable artificial kidney: technical requirements and potential solutions. Expert Rev Med Devices 8:567–579
Davenport A et al (2007) A wearable haemodialysis device for patients with end-stage renal failure: a pilot study. Lancet 370:2005–2010
Ronco C et al (2011) The future of the artificial kidney: moving towards wearable and miniaturized devices. Nefrologia 31:9–16
Humes HD et al (2004) Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acute renal failure. Kidney Int 66:1578–1588
Medical Devices Directive 2007/47/EC of Sept. 5th, 2007, amending Council Directive 93/42/EEC. Official J Eur Union 247(L): 21–55, 2007
Lodi CA et al (2010) Multidisciplinary evaluation for severity of hazards applied to hemodialysis devices: an original risk analysis method. Clin J Am Soc Nephrol 5(11):2004–2017
ISO 16527: Health informatics—HL7 Personal Health Record System Functional Model, 1nd Ed., Geneva, International Organization for Standardization, 2016
Acknowledgments
The authors acknowledge the financial support by Fondazione Studi Universitari di Vicenza (FSU) and Fondazione Cariverona through a Ph.D. scholarship and the research grant “RAP”.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this paper
Cite this paper
Boschetti, G. et al. (2017). Conceptual Design of a Mechatronic Biomedical Wearable Device for Blood Ultrafiltration. In: Boschetti, G., Gasparetto, A. (eds) Advances in Italian Mechanism Science. Mechanisms and Machine Science, vol 47. Springer, Cham. https://doi.org/10.1007/978-3-319-48375-7_10
Download citation
DOI: https://doi.org/10.1007/978-3-319-48375-7_10
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-48374-0
Online ISBN: 978-3-319-48375-7
eBook Packages: EngineeringEngineering (R0)