Abstract
Nanotechnology era comprises an array of food and nutritional supplements referred as nutraceuticals which are transformed to bio-enhanced “Nanoceuticals”. As India’s economy is booming and purchase is on the rise, India’s nutraceuticals market is expected to reach around US$4 billion by 2018.
These products find plentiful space to broaden their therapeutic segment at lab scale, however, their translation to clinics often has resulted in a failure. Latter being assigned to the poor bioavailability of these nutraceuticals, attributed to their poor solubility and permeability, photo-degradation and lower available systemic concentrations. Nanoprocessing of these products may increase their therapeutic value and provide protection from free radical damage. Further, it enhances their antimutagenic potential, provides better neurological functioning, improves endocrine and immunomodulatory functions, in addition to metabolism and digestion, and possesses better anti-aging properties, as a result of enhanced bioavailability. Though no alteration in the chemical structure of the nutrient occurs, however a change in its action for better utilisation and absorption in the body is viewed as a consequence of this translation.
Successful nano-transformation is visioned as a result of approvals from US-FDA which is otherwise sought to be the major milestone for commercialisation of the nano-based product. The Indian market is flooded with a range of nanoceutical products which are delivered via various nanodelivery systems including polymeric and lipidic nanoparticles, micelles, phospholipid complexes and the same is expected to rise in the coming years. As maintaining a good health is our prima-facie responsibility, the shortcomings of the technology must be understood. This book chapter exposes the successful journey for transforming a nutraceutical to nanoceutical and their impact on health of the individual.
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Kakkar, V., Modgill, N., Kumar, M. (2016). From Nutraceuticals to Nanoceuticals. In: Ranjan, S., Dasgupta, N., Lichtfouse, E. (eds) Nanoscience in Food and Agriculture 3. Sustainable Agriculture Reviews, vol 23. Springer, Cham. https://doi.org/10.1007/978-3-319-48009-1_7
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