Temporal Excitation Patterns on the Cerebral Cortex as a Result of Migraine Modeling

  • Julia M. KroosEmail author
  • Ibai Diez
  • Jesus M. Cortes
  • Sebastiano Stramaglia
  • Luca Gerardo-Giorda
Conference paper
Part of the Springer Proceedings in Physics book series (SPPHY, volume 191)


The complex, highly individual, geometry of the cerebral cortex in humans presents a major challenge in studying the spreading of spontaneous neuronal activity. Recent computational advances [1] allow to simulate the propagation of depolarization waves on the macroscale and for individual geometries, reconstructed from accurate medical imaging as MRI, with high levels of detail. In this paper we take advantage of such technique to study the temporal excitation patterns that follow the passage of a depolarization wave on the cerebral cortex.


Firing Rate Transient Global Amnesia Excitation Pattern Excited Region Depolarization Wave 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by the Bizkaia Talent and European Commission through COFUND under the grant BRAhMS – Brain Aura Mathematical Simulation– (AYD-000-285), and also by the Basque Government through the BERC 2014–2017 program, and by the Spanish Ministry of Economics and Competitiveness MINECO: BCAM Severo Ochoa excellence accreditation SEV-2013-0323. JMC acknowledges financial support from Ikerbasque: The Basque Foundation for Science and Euskampus at UPV/EHU.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Julia M. Kroos
    • 1
    Email author
  • Ibai Diez
    • 2
  • Jesus M. Cortes
    • 3
    • 4
    • 5
  • Sebastiano Stramaglia
    • 6
    • 7
  • Luca Gerardo-Giorda
    • 8
  1. 1.Basque Center for Applied MathematicsBasque Country, BilbaoSpain
  2. 2.Biocruces Health Research InstituteCruces University HospitalBarakaldoSpain
  3. 3.Biocruces Health Research Institute BarakaldoBarakaldoSpain
  4. 4.Departamento de Biologia Celular e HistologiaUniversity of the Basque CountryLeioaSpain
  5. 5.Ikerbasque: The Basque Foundation for ScienceBilbaoSpain
  6. 6.Dipartimento di FisicaUniversità di BariBariItaly
  7. 7.INFN, Sezione di BariBariItaly
  8. 8.Basque Center for Applied MathematicsBilbaoSpain

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