Ocular Delivery of Proteins and Peptides
Biotechnology is steadily becoming an important component of the pharmaceutical industry. The numbers of protein and peptide ocular based drugs being developed have increased. The technique to formulate peptide or protein ocular drugs is very different from formulating conventional small molecule drugs. Additionally, the delivery of a peptide or protein-based drugs is particularly challenging due to the issues of protein instability. This chapter discusses the development of proteins and peptides for ocular delivery with an emphasis on their specific considerations and challenges, and a role of specific proteins such as alpha crystallins and thymosin β4 in ocular drug delivery. Possible routes of protein ocular drug delivery are also discussed.
KeywordsOcular peptides delivery Proteins delivery Peptides delivery Route of delivery
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