Anatomy of the Eye and Common Diseases Affecting the Eye

  • Evelyn Addo
  • Oluyemisi A. Bamiro
  • Rodney Siwale


The human eye is a unique part of the human body that has been described as the window to the human soul. The eye being a complex organ is broadly divided into two segments—anterior and posterior segments. Each of these broad segments has specific disease conditions associated with them. This chapter will extensively describe these various components of the eye and the common disease conditions associated with it.


Anatomy Physiology Eye diseases 


  1. Agarwal R, Iezhitsa I, Agarwal P, Nasir NAA, Razali N, Alyautdin R, Ismail NM (2016) Liposomes in topical ophthalmic drug delivery: an update. Drug Deliv 23(4):1075–1091Google Scholar
  2. Albert DM, Gamm DM (2016) Encyclopaedia britannica available on Cited 28 May 2016
  3. Baylor DA, Lamb TD, Yau KW (1979) Responses of retinal rods to single photons. J Physiol 288:613–634PubMedPubMedCentralGoogle Scholar
  4. Beatty S, Koh H, Phil M, Henson D, Boulton M (2000) The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 45:115–134CrossRefGoogle Scholar
  5. Borges-Giampani AS, Junior JG (2013). Anatomy of ciliary body, ciliary processes, anterior chamber angle and collector vessels. doi: 10.5772/52780Google Scholar
  6. Bruce Shields M. (1997) Aqueous humor dynamics: anatomy and Physiology. In Textbook of glaucoma, 4th edn. Williams & Wilkins, pp 5–31Google Scholar
  7. Coleman HR, Chan CC, Ferris FL, Chew EY (2008) Age-related macular degeneration. Lancet 372:1835–1845CrossRefGoogle Scholar
  8. DelMonte DW, Kim T (2011) Anatomy and physiology of the cornea. J Cataract Refract Surg 37:588–598. Available on…/49848146. Retrieved 18 May 2016CrossRefGoogle Scholar
  9. Foster CS (2015) Dry eye syndrome (Medscape Homepage. On the internet). Available on Updated 15 July 2015, cited 6 June 2016
  10. Goel M, Picciani RG, Lee RK, Bhattacharya SK (2010) Aqueous humor dynamics: a review. Open Ophthalmol J 4:52–59CrossRefGoogle Scholar
  11. Gong H, Tripathi RC, Tripathi BJ (1996) Morphology of the aqueous outflow pathway. Microsc Res Tech 33(4):336–367CrossRefGoogle Scholar
  12. Gong HY, Trinkaus-Randall V, Freddo TF (1989) Ultrastructural immunocytochemical localization of elastin in normal human trabecular meshwork. Curr Eye Res 8(10):1071–1082CrossRefGoogle Scholar
  13. Iwasaki M, Inomara H (1986) Relation between superficial capillaries and foveal structures in the human retina. Invest Ophthalmol Vis Sci 27:1698–1705PubMedGoogle Scholar
  14. Jager RD, Mieler WF, Miller JW (2008) Age-related macular degeneration. N Engl J Med 358:2606–2617CrossRefGoogle Scholar
  15. Kolb H (1991) The neural organization of the human retina. In: Heckenlively JR, Arden GB (eds) Principles and practices of clinical electrophysiology of vision. Mosby Year Book Inc, St. Louis, pp 25–52Google Scholar
  16. Llobet A, Gasull X, Gual A (2003) Understanding trabecular meshwork physiology: a key to the control of intraocular pressure? News Physiol Sci. 18. Available on Cited 2 June 2016
  17. Majumder PD (2008). Anatomy of conjunctiva (eophtha homepage on the internet). Available on Updated 27 July 2008, cited 17 May 2016
  18. Nationaleyeinstitute. Available
  19. Nickla DL, Wallman J (2010) The multifunctional choroid. Prog Retin Eye Res 29(2):144–168CrossRefGoogle Scholar
  20. Noell WK, Walker VS, Kang BS, Berman S (1966) Retinal damage by light in rats. Invest Ophthalmol 5:450–473PubMedGoogle Scholar
  21. Ramrattan RS, Van der Schaft TL, Mooy CM, De Bruijn WC, Mulder PGH, De Jong P (1994) Morphometric analysis of Bruch’s membrane, the choriocapillaris and the choroid in aging. Invest Ophthalmol Vis Sci 35:2857–2864PubMedGoogle Scholar
  22. Sires B (1997) Orbital and ocular anatomy. In: Wright Ed (ed) Textbook of ophthalmology. Williams and Wilkins, Baltimore, MDGoogle Scholar
  23. Vaishya RD, Khurana V, Patel S, Mitra AK (2014) Controlled ocular drug delivery with nanomicelles. Wiley Interdiscip Rev Nanomed Nanobiotechnol 6(5):422–437. doi: 10.1002/wnan.1272CrossRefPubMedPubMedCentralGoogle Scholar
  24. Van Buskirk EM (1986) Clinical Atlas of Glaucoma. WB Saunders, PhiladelphiaGoogle Scholar
  25. Vision RX Encyclopaedia (2005) (Homepage on the internet) Conjunctivae. Cited 18 May 2016
  26. Yu WY, Sheridan C, Grierson I, Mason S, Kearns V, Lo ACY, Wong D (2011). Progenitors for the corneal endothelium and trabecular meshwork: a potential source for personalized stem cell therapy in corneal endothelial diseases and glaucoma. J Biomed Biotechnol. Article ID 412743. doi: 10.1155/2011/412743CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2016

Authors and Affiliations

  • Evelyn Addo
    • 1
  • Oluyemisi A. Bamiro
    • 2
    • 3
  • Rodney Siwale
    • 4
  1. 1.School of Social Work, College of Education & Human StudiesUnion UniversityJacksonUSA
  2. 2.Union University School of PharmacyJacksonUSA
  3. 3.Department. Pharmaceutics and Pharmaceutical TechnologyOlabisi Onabanjo UniversityAgo IwoyeNigeria
  4. 4.Department of Pharmaceutical SciencesCollege of Pharmacy, Western New England College of PharmacySpringfieldUSA

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