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Platelet Function Tests

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Platelets in Thrombotic and Non-Thrombotic Disorders

Abstract

Many platelet function assays have been developed over the last century in an attempt to capture the natural ability of platelets to form aggregates in response to vascular injury. From physiological assays, such as the bleeding time, to diagnostic assays used within specialized hematology departments, to point-of-care assays that are intended as clinical decision aids on wards and in operating rooms, and finally to high-throughput deep phenotyping assays intended for precision medicine, platelet function assays have become increasingly commonplace in many settings. This chapter presents an overview of the most commonly used platelet functions assays and discusses important variables to take into account when performing platelet function testing, ranging from pre-analytical issues to the clinical utility of individual tests.

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Authors and Affiliations

  1. Faculté de pharmacie, Université de Montréal, C.P. 6128, succursale Centre-ville, Montréal, QC, Canada, H3C 3J7

    Marie Lordkipanidzé

  2. Research Center, Montreal Heart Institute, 5000 rue Bélanger, Montréal, QC, Canada, H1T 1C8

    Marie Lordkipanidzé

  3. Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK

    Paul Harrison

Authors
  1. Marie Lordkipanidzé
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  2. Paul Harrison
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Correspondence to Marie Lordkipanidzé .

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Editors and Affiliations

  1. Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia , Perugia, Italy

    Paolo Gresele

  2. Houston Methodist Hospital , Houston, Texas, USA

    Neal S. Kleiman

  3. Bloodworks Northwest, University of Washington , Seattle, Washington, USA

    José A. Lopez

  4. Sackler Inst of Pulmonary Pharmacol, King’s College London, London, United Kingdom

    Clive P. Page

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Lordkipanidzé, M., Harrison, P. (2017). Platelet Function Tests. In: Gresele, P., Kleiman, N., Lopez, J., Page, C. (eds) Platelets in Thrombotic and Non-Thrombotic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-47462-5_38

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