Skip to main content

Medications, Alcohol, and Aging

  • Chapter
  • First Online:
  • 915 Accesses

Abstract

The decision to consume alcohol involves weighing the benefits and risks of alcohol use. For older adults, the risks associated with consuming alcohol may be higher due to changes in physiology associated with aging, the development of chronic health conditions, and the concurrent use of alcohol-interacting medications. Concurrent use of alcohol and certain medication classes can result in falls, gastrointestinal bleeding, and other negative outcomes. Of particular concern are psychoactive medications such as sedatives and opiates, anticoagulants such as warfarin, and antihypertensive agents. Individuals with poor sleep quality and pain may be at increased risk of alcohol–medication interactions when alcohol is used to manage sleep or pain along with prescription or over-the-counter medications. Older adults may not receive adequate information about their medications in the context of alcohol use to make an informed decision about concurrent use. Many older adults do not discuss alcohol use with their healthcare providers and written warnings, such as over-the-counter packaging, may not reflect age-specific recommendations. Raising awareness among consumers and healthcare providers is an important step to assist older adults in making informed decisions about concurrent use of alcohol and medications.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Administration on Aging, Administration for Community Living, U.S. Department of Health and Human Services. A profile of older Americans: 2014. http://www.aoa.acl.gov/Aging_Statistics/Profile/2014/docs/2014-Profile.pdf.

  2. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA. 2008;300:2867–78.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. National Center for Health Statistics. Health, United States, 2013: with special feature on prescription drugs. Hyattsville; 2014.

    Google Scholar 

  4. Substance Abuse and Mental Health Services Administration. Results from the 2013 national survey on drug use and health: summary of national findings. NSDUH Series H-48, HHS Publication No. (SMA) 14-4863. Rockville: Substance Abuse and Mental Health Services Administration; 2014.

    Google Scholar 

  5. Wilson SR, Knowles SB, Huang Q, Fink A. The prevalence of harmful and hazardous alcohol consumption in older U.S. adults: data from the 2005–2008 National Health and Nutrition Examination Survey (NHANES). J Gen Intern Med. 2014;29:312–9.

    Article  PubMed  Google Scholar 

  6. Blow FC, Barry KL. Alcohol and substance misuse in older adults. Curr Psychiatry Rep. 2012;14:310–9.

    Article  PubMed  Google Scholar 

  7. Sacco P, Burruss K, Smith CA, Kuerbis A, Harrington D, Moore AA, Resnick B. Drinking behavior among older adults at a continuing care retirement community: affective and motivational influences. Aging Ment Health. 2015;19:279–89.

    Article  PubMed  Google Scholar 

  8. Fishleder S, Schonfeld L, Corvin J, Tyler S, VandeWeerd C. Drinking behavior among older adults in a planned retirement community: results from the Villages survey. Int J Geriatr Psychiatry. 2015;31(5):536–43. doi: 10.1002/gps.4359.

    Google Scholar 

  9. Hajjar ER, Gray SL, Slattum PW, Starner CI, Maher Jr RL, Hersh LR, Hanlon JT. eChapter 8. Geriatrics. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey L, editors. Pharmacotherapy: a pathophysiologic approach, 9e. New York: McGraw-Hill; 2014. http://accesspharmacy.mhmedical.com/content.aspx?bookid=689&Sectionid=48811433. Accessed 23 Jan 2016.

  10. Reeve E, Wiese MD, Mangoni AA. Alterations in drug disposition in older adults. Expert Opin Drug Metab Toxicol. 2015;11:491–508.

    Article  PubMed  Google Scholar 

  11. Hubbard RE, O’Mahony MS, Woodhouse KW. Medication prescribing in frail older people. Eur J Clin Pharmacol. 2013;69:319–26.

    Article  PubMed  Google Scholar 

  12. Hines LE, Murphy JE. Potentially harmful drug-drug interactions in the elderly: a review. Am J Geriatr Pharmacother. 2011;9:364–7.

    Article  CAS  PubMed  Google Scholar 

  13. Dharia SP, Slattum PW. Alcohol, medications and the older adult. Consult Pharm. 2011;26:837–44.

    Article  PubMed  Google Scholar 

  14. Hennessy S, Leonard CE, Gagne JJ, Flory JH, Han X, Brensinger CM, Bilker WB. Pharmacoepidemiologic methods for studying the health effects of drug-drug interactions. Clin Pharmacol Ther. 2016;91:92–100.

    Article  Google Scholar 

  15. PL Detail-Document. Alcohol and drug interactions. Pharmacist’s Letter/Prescriber’s Letter. December 2015.

    Google Scholar 

  16. Breslow RA, Dong C, White A. Prevalence of alcohol-interactive prescription medication use among current drinkers: United States, 1999 to 2010. Alcohol Clin Exp Res. 2015;39:317–79.

    Article  Google Scholar 

  17. Qato DM, Manzoor BS, Lee TA. Drug-alcohol interactions in older U.S. adults. J Am Geriatr Soc. 2015;63:2324–31.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Pringle KE, Ahern FM, Heller DA, Gold CH, Brown TV. Potential for alcohol and prescription drug interactions in older people. J Am Geriatr Soc. 2005;53:1930–6.

    Article  PubMed  Google Scholar 

  19. Ilomäki J, Gnjidic D, Hilmer SN, Le Couteur DG, Naganathan V, Cumming RG, Waite LM, Seibel MJ, Blyth FM, Handelsman DJ, Bell JS. Psychotropic drug use and alcohol drinking in community-dwelling older Australian men: the CHAMP study. Drug Alcohol Rev. 2013;32:218–22.

    Article  PubMed  Google Scholar 

  20. Immonen S, Valvanne J, Pitkala KH. The prevalence of potential alcohol-drug interactions in older adults. Scan J Prim Health Care. 2013;31:73–8.

    Article  Google Scholar 

  21. Cousins G, Galvin R, Flood M, Kennedy MC, Motterlini N, Henman MC, Kenny RA, Fahey T. Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing. BMC Geriatr. 2014;14:57–67.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Fink A, Morton SC, Beck JC, Hays RD, Spritzer K, Oishi S, Moore AA. The Alcohol-Related Problems Survey: identifying hazardous and harmful drinking in older primary care patients. J Am Geriatr Soc. 2002;50:1717–22.

    Article  PubMed  Google Scholar 

  23. Barnes AJ, Moore AA, Xu H, Ang A, Tallen L, Mirkin M, Ettner SL. Prevalence and correlates of at-risk drinking among older adults: the project SHARE study. J Gen Intern Med. 2010;25:840–6.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Moore AA, Giuli L, Gould R, Hu P, Zhou K, Reuben D, Greendale G, Karlamangla A. Alcohol use, comorbidity, and mortality. J Am Geriatr Soc. 2006;54:757–62.

    Article  PubMed  Google Scholar 

  25. Mohanty M. Alcohol and medication use in community-dwelling older adults: understanding the effect of alcohol and central nervous system-acting medications on the risk for falls [Dissertation]. Richmond: Virginia Commonwealth University; 2013.

    Google Scholar 

  26. Curkovic M, Dodig-Curkovic K, Eric AP, Kralik K, Pivac N. Psychotropic medications in older adults: a review. Psychiatr Danub. 2016;28(1):13–24.

    PubMed  Google Scholar 

  27. Wiergenga PC, Buurman BM, Parlevliet JL, van Munster BC, Smorenburg SM, Inouye SK, de Rooij SE. Association between acute geriatric syndromes and medication-related hospital admissions. Drugs Aging. 2012;29:691–9.

    Google Scholar 

  28. Immonen S, Valvanne J, Pitkala KH. Alcohol use of older adults: drinking alcohol for medicinal purposes. Age Ageing. 2011;40:633–7.

    Article  PubMed  Google Scholar 

  29. Gilson KM, Bryant C, Judd F. The hidden harms of using alcohol for pain relief in older adults. Int Psychogeriatr. 2014;26:1929–30.

    Article  PubMed  Google Scholar 

  30. Zale EL, Maisto SA, Ditre JW. Interrelations between pain and alcohol: an integrative review. Clin Psychol Rev. 2015;37:57–71.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Gooneratne NS, Tavaria A, Patel N, Madhusudan L, Nadaraja D, Onen F, Richards KC. Perceived effectiveness of diverse sleep treatments in older adults. J Am Geriatr Soc. 2011;59:297–303.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Min Y, Kirkwood CK, Mays D, Slattum PW. The effect of sleep medication use and poor sleep quality on risk of falls in community-dwelling older adults. Drugs Aging. 2016;33:151–8.

    Article  CAS  PubMed  Google Scholar 

  33. McKnight-Eily LR, Liu Y, Brewer RD, et al. Vital signs: communication between health professionals and their patients about alcohol use—44 states and the District of Columbia, 2011. MMWR Morb Mortal Wkly Rep. 2014;63(1):16–22.

    PubMed  Google Scholar 

  34. Zanjani F, Hoogland AI, Downer BG. Alcohol and prescription drug safety in older adults. Drug Healthc Pat Safety. 2013;5:13–27.

    Article  CAS  Google Scholar 

  35. Crome I, Li TK, Rao R, Wu LT. Alcohol limits in older people. Addiction. 2012;107:1541–3.

    Article  PubMed  Google Scholar 

  36. Kuerbis AN, Yuan SE, Borok J, LeFevre PM, Kim GS, Lum D, Ramirez KD, Liao DH, Moore AA. Testing the initial efficacy of a mailed screening and brief feedback intervention to reduce at-risk drinking in middle-aged and older adults: the comorbidity alcohol risk evaluation study. J Am Geriatr Soc. 2015;63:321–6.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Ettner SL, Xu H, Duru OK, Ang A, Tseng CH, Tallen L, Barnes A, Mirkin M, Ransohoff K, Moore AA. The effect of an educational intervention on alcohol consumption, at-risk drinking, and health care utilization in older adults: the project SHARE study. J Stud Alcohol Drugs. 2014;75:447–57.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Benza AT, Calvert S, McQuown CB. Prevention BINGO: reducing medication and alcohol use risks for older adults. Aging Ment Health. 2010;14:1008–14.

    Article  PubMed  Google Scholar 

  39. Schonfeld L, King-Kallimanis BL, Duchene DM, Etheridge RL, Herrera JR, Barry KL, Lynn N. Screening and brief intervention for substance misuse among older adults: the Florida BRITE project. Am J Public Health. 2010;100:108–14.

    Article  PubMed  PubMed Central  Google Scholar 

  40. NIAAA. Harmful interactions: mixing alcohol with medicines. NIH Publication No. 13–5329 (Revised). 2014.

    Google Scholar 

  41. Weathermon R, Crabb DW. Alcohol and medication interactions. Alcohol Res Health. 1999;23(1):40–54.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Patricia W. Slattum Pharm.D., Ph.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this chapter

Cite this chapter

Slattum, P.W., Hassan, O.E. (2016). Medications, Alcohol, and Aging. In: Kuerbis, A., Moore, A., Sacco, P., Zanjani, F. (eds) Alcohol and Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-47233-1_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-47233-1_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-47231-7

  • Online ISBN: 978-3-319-47233-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics