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Grading and Treatment of Acute Graft-Versus-Host Disease

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Atlas of Graft-versus-Host Disease

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Abstract

Acute graft-versus-host disease (aGVHD) remains a major complication and is the leading cause of nonrelapse mortality after allogeneic hematopoietic stem cell transplantation (HSCT). The most commonly involved organ is the skin, providing an opportunity for clinicians to recognize and intervene in this potentially fatal process. Appropriate grading of severity is critical to determine treatment. Therapy for advanced aGVHD is challenging. This chapter reviews the evidence for commonly studied and novel approaches that hold promise.

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Authors and Affiliations

  1. Department of Dermatology, Brigham and Women’s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA

    Anar Mikailov & Molly Plovanich

  2. Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA

    Arturo P. Saavedra

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  1. Anar Mikailov
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Correspondence to Anar Mikailov .

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  1. Division of Dermatology, City of Hope National Medical Center Division of Dermatology, Durante, California, USA

    Jonathan A. Cotliar

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Mikailov, A., Plovanich, M., Saavedra, A.P. (2017). Grading and Treatment of Acute Graft-Versus-Host Disease. In: Cotliar, J. (eds) Atlas of Graft-versus-Host Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-46952-2_6

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