Bihemispheric Cerebellar Spiking Network Model to Simulate Acute VOR Motor Learning
The vestibuloocular reflex (VOR) is an adaptive control system. The cerebellar flocculus is intimately involved in the VOR adaptive motor control. The cerebellar flocculus has bihemispheric architecture and the several lines of unilateral lesion study indicated that each cerebellar hemisphere plays different roles in the leftward and rightward eye movement control and learning. However, roles of bihemispheric cerebellar architecture underlying the VOR motor learning have not been fully understood. Here we configure an anatomically/physiologically plausible bihemispheric cerebellar neuronal network model composed of spiking neurons as a platform to unveil roles and capacities of bihemispheric cerebellar architecture in the VOR motor learning.
KeywordsEye movement Spike timing dependent plasticity Computer simulation Cerebellar lesion
This work was supported in part by JSPS KAKENHI Grant-In-Aid for Scientific Research (B) (24300115 and 16H02901, YH) and Grant-in-Aid for Young Scientists (B) (15K16086, KI).
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