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Operant Conditioning of the Tibialis Anterior Motor Evoked Potential to Transcranial Magnetic Stimulation

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Converging Clinical and Engineering Research on Neurorehabilitation II

Part of the book series: Biosystems & Biorobotics ((BIOSYSROB,volume 15))

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Abstract

The activity of corticospinal pathways is important in movement control and its plasticity is essential for learning motor skills and re-learning them after spinal cord injury (SCI) and other CNS disorders. After SCI, corticospinal excitability and connectivity diminish, as SCI disturbs supraspinal connections. However, this can be reversed. Thus, if there is a way to enhance the function of corticospinal pathways, motor function recovery may be improved. The central hypothesis of this study is that operant conditioning of the corticospinal motor evoked potential can strengthen corticospinal connectivity and thereby improve motor function recovery in people after incomplete SCI.

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References

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Acknowledgments

This work was supported by the New York State Spinal Cord Injury Research Trust (C023685), the Morton Cure Paralysis Fund, the National Institute of Neurological Disorders and Stroke (NS0695 51), and the National Institute of General Medical Sciences (GM104941 to Binder-MacLeod).

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Authors and Affiliations

  1. Christie Evoked Potential Operant Conditioning Laboratory, College of Health Professions, Medical University of South Carolina, Charleston, USA

    Aiko K. Thompson, Rachel H. Cote & Christina R. Thompson

Authors
  1. Aiko K. Thompson
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  2. Rachel H. Cote
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  3. Christina R. Thompson
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Corresponding author

Correspondence to Aiko K. Thompson .

Editor information

Editors and Affiliations

  1. Cajal Institute, Spanish National Research Council Cajal Institute, Madrid, Spain

    Jaime Ibáñez

  2. Cajal Institute, Spanish National Research Council Cajal Institute, Madrid, Spain

    José González-Vargas

  3. Avda. de la Universidad s/n, Universidad Miguel Hernández de Elche Avda. de la Universidad s/n, Elche, Spain

    José María Azorín

  4. Cullen College of Engineering, University of Houston Cullen College of Engineering, Houston, USA

    Metin Akay

  5. Cajal Institute, Spanish National Research Council Cajal Institute, Madrid, Spain

    José Luis Pons

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Thompson, A.K., Cote, R.H., Thompson, C.R. (2017). Operant Conditioning of the Tibialis Anterior Motor Evoked Potential to Transcranial Magnetic Stimulation. In: Ibáñez, J., González-Vargas, J., Azorín, J., Akay, M., Pons, J. (eds) Converging Clinical and Engineering Research on Neurorehabilitation II. Biosystems & Biorobotics, vol 15. Springer, Cham. https://doi.org/10.1007/978-3-319-46669-9_6

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  • DOI: https://doi.org/10.1007/978-3-319-46669-9_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46668-2

  • Online ISBN: 978-3-319-46669-9

  • eBook Packages: EngineeringEngineering (R0)

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