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Clinical Management of Transplant Recipients

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The Pathology of Cardiac Transplantation

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Abstract

Decades after the first heart transplant was performed, the clinical management of heart transplant recipients is still challenging. This chapter will recount the main aspects of selection of heart failure patients for transplantation. A summary of the main mechanisms of the most commonly used immunosuppressive drugs is given, as well as the main antirejection protocols, including related problems. Management of heart transplant recipients involves not only immunosuppression but also a global medical approach, according to the different phases of transplantation: during surgery, in the early postoperative period, and in the long-term follow-up. Some insights into the most frequently used instrumental diagnostic techniques and into the new research topics are also briefly presented.

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Author information

Authors and Affiliations

  1. Heart Failure and Heart Transplant Program, Cardiology Unit, S. Orsola Malpighi University Hospital, Bologna, Italy

    Marco Masetti PhD & Francesco Grigioni MD, PhD

Authors
  1. Marco Masetti PhD
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  2. Francesco Grigioni MD, PhD
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Corresponding author

Correspondence to Francesco Grigioni MD, PhD .

Editor information

Editors and Affiliations

  1. Cardiovascular and Cardiac Transplant Pathology Program Department of Pathology, Sant’Orsola-Malpighi University Hospital, Bologna, Italy

    Ornella Leone

  2. Pathology of Cardiac Transplantation and Regenerative Medicine Unit Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy

    Annalisa Angelini

  3. Department of Pathology, Hôpital Européen Georges Pompidou, Paris, France

    Patrick Bruneval

  4. Heart Failure and Heart Transplant Program, Cardiology Unit, Sant’Orsola-Malpighi University Hospital, Bologna, Italy

    Luciano Potena

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Masetti, M., Grigioni, F. (2016). Clinical Management of Transplant Recipients. In: Leone, O., Angelini, A., Bruneval, P., Potena, L. (eds) The Pathology of Cardiac Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-46386-5_11

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  • DOI: https://doi.org/10.1007/978-3-319-46386-5_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46384-1

  • Online ISBN: 978-3-319-46386-5

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