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Nuclear Magnetic Resonance

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Food Analysis

Part of the book series: Food Science Text Series ((FSTS))

Abstract

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique with a wide variety of applications, from structural elucidation of complex molecules, to 3D-imaging of fresh tissue, to simple ingredient assays for quality assurance. NMR differs from most other forms of spectroscopy because the nucleus is the subject of analysis and the excitation step uses radio-frequency electromagnetic energy. Whereas other spectroscopy techniques may be used to determine the nature of the functional groups present in a sample, only NMR spectroscopy can provide the data necessary to determine the complete structure of a molecule. The NMR instrument consists of a cryomagnet with the transmitter and receiver antennae in the central bore, an electronics console with the transmitter and receiver hardware, and a data/work station that controls all the functions of the instrument. In addition to NMR spectrometers, with both solids and liquids applications, there are other related instruments, such as magnetic resonance imaging (MRI), that are based on the same principles, but yield different information. This chapter covers the basic principles and applications of NMR spectroscopy, as well as a brief description of relaxometry, MRI, and the use of NMR as part of a rapid moisture and fat analysis system.

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References

  1. Li J, Kang J, Wang L, Li Z, Wang R, Chen ZX, Hou GG (2012) Effect of water migration between arabinoxylans and gluten on baking quality of whole wheat bread detected by magnetic resonance imaging (MRI). J Agric Food Chem 60(26):6507–6514

    Article  CAS  PubMed  Google Scholar 

  2. Mazhar M, Joyce D, Cowin G, Brereton I, Hofman P, Collins R, Gupta M (2015) Non-destructive 1H-MRI assessment of flesh bruising in avocado (Persea americana M.) cv. Hass. Postharvest Biol Tech 100:33–40

    Article  Google Scholar 

  3. Spiteri M, Jamin E, Thomas F, Rebours A, Lees M, Rogers KM, Rutledge DN (2015) Fast and global authenticity screening of honey using 1H-NMR profiling. Food Chem 189:60–66

    Article  CAS  PubMed  Google Scholar 

  4. Siciliano C, Belsito E, De Marco R, Di Gioia ML, Leggio A, Liguori A (2013) Quantitative determination of fatty acid chain composition in pork meat products by high resolution 1 H NMR spectroscopy. Food Chem 136(2):546–554

    Article  CAS  PubMed  Google Scholar 

  5. Ohtsuki T, Sato K, Sugimoto N, Akiyama H, Kawamura Y (2012) Absolute quantification for benzoic acid in processed foods using quantitative proton nuclear magnetic resonance spectroscopy. Talanta 99:342–348

    Article  CAS  PubMed  Google Scholar 

  6. Bosmans GM, Pareyt B, Delcour JA (2016) Non-additive response of blends of rice and potato starch during heating at intermediate water contents: A differential scanning calorimetry and proton nuclear magnetic resonance study. Food Chem 192:586–595

    Article  CAS  PubMed  Google Scholar 

  7. Wei F, Furihata K, Hu F, Miyakawa T, Tanokura M (2010) Complex mixture analysis of organic compounds in green coffee bean extract by two‐dimensional NMR spectroscopy. Magnetic Resonance in Chemistry 48(11):857–865

    Article  CAS  PubMed  Google Scholar 

  8. Sciubba F, Di Cocco ME, Gianferri R, Impellizzeri D, Mannina L, De Salvador FR, Venditti A, Delfini M (2014) Metabolic profile of different Italian cultivars of hazelnut (Corylus avellana) by nuclear magnetic resonance spectroscopy. Natural Product Research. 28(14):1075–1081

    Article  CAS  PubMed  Google Scholar 

  9. Cao R, Nonaka A, Komura F, Matsui T (2015) Application of diffusion ordered-1 H-nuclear magnetic resonance spectroscopy to quantify sucrose in beverages. Food Chem 171:8–12

    Article  CAS  PubMed  Google Scholar 

  10. Dugo G, Rotondo A, Mallamace D, Cicero N, Salvo A, Rotondo E, Corsaro C (2015) Enhanced detection of aldehydes in Extra-Virgin Olive Oil by means of band selective NMR spectroscopy. Physica A: Statistical Mechanics and its Applications 420:258–264

    Article  CAS  Google Scholar 

  11. Colombo C, Aupic C, Lewis AR, Pinto BM (2015) In situ determination of fructose isomer concentrations in wine using 13C quantitative nuclear magnetic resonance spectroscopy. J Agric Food Chem 63(38):8551–9

    Article  CAS  PubMed  Google Scholar 

  12. Haque E, Bhandari BR, Gidley MJ, Deeth HC, Whittaker AK (2015) Change in molecular structure and dynamics of protein in milk protein concentrate powder upon ageing by solid-state carbon NMR. Food Hydrocolloids 44:66–70

    Article  CAS  Google Scholar 

  13. Cai H-H, Chen H, Lin Y-L, Feng J-H, Cui X-H, Chen Z (2015) Feasibility of ultrafast intermolecular single-quantum coherence spectroscopy in analysis of viscous liquid foods. Food Anal Methods 8(7):1682–90

    Article  Google Scholar 

  14. Pereira FMV, Pflanzer SB, Gomig T, Gomes CL, de Felicio PE, Colnago LA (2013) Fast determination of beef quality parameters with time-domain nuclear magnetic resonance spectroscopy and chemometrics. Talanta 108:88–91

    Article  CAS  PubMed  Google Scholar 

  15. Serial M, Canalis MB, Carpinella M, Valentinuzzi M, León A, Ribotta P, Acosta RH (2016) Influence of the incorporation of fibers in biscuit dough on proton mobility characterized by time domain NMR. Food Chem 192:950–957

    Article  CAS  PubMed  Google Scholar 

  16. Pereira FMV, Rebellato AP, Pallone JAL, Colnago LA (2015) Through-package fat determination in commercial samples of mayonnaise and salad dressing using time-domain nuclear magnetic resonance spectroscopy and chemometrics. Food Control 48:62–6

    Article  Google Scholar 

  17. Bemer HL, Limbaugh M, Cramer ED, Harper WJ, Maleky F (2016) Vegetable organogels incorporation in cream cheese products. Food Res Intl 85:67–75

    Article  CAS  Google Scholar 

  18. Pérez EMS, Iglesias MJ, Ortiz FL, Pérez IS, Galera MM (2010) Study of the suitability of HRMAS NMR for metabolic profiling of tomatoes: Application to tissue differentiation and fruit ripening. Food Chem 122(3):877–87

    Article  Google Scholar 

  19. Heude C, Lemasson E, Elbayed K, Piotto M (2015) Rapid assessment of fish freshness and quality by 1H HR-MAS NMR spectroscopy. Food Anal Methods 8(4):907–15

    Article  Google Scholar 

  20. Bertocchi F, Paci M (2008) Applications of high-resolution solid-state NMR spectroscopy in food science. J Agric Food Chem 56(20):9317–27

    Article  CAS  PubMed  Google Scholar 

Resource Materials

  • Berger S, Braun S (2004) 200 and more NMR experiments: a practical course. Wiley–VCH, Weinheim, Germany

    Google Scholar 

  • Farhat IA, Belton PS, Webb GA (2007) Magnetic resonance in food science: from molecules to man. The Royal Society of Chemistry, Cambridge, England

    Book  Google Scholar 

  • Günther H (1995) NMR spectroscopy, 2nd edn. Wiley, New York

    Google Scholar 

  • Hills B (1998) Magnetic resonance imaging in food science. Wiley, New York

    Google Scholar 

  • Jacobsen NE (2007) NMR spectroscopy explained: simplified theory, applications and examples for organic chemistry and structural biology. Wiley, New York

    Book  Google Scholar 

  • McMurry JE (2007) Organic chemistry, 7th edn. Brooks-Cole, Salt Lake City, UT

    Google Scholar 

  • Skoog DA, Holler FJ, Crouch SR (2007) Principles of instrumental analysis, 6th edn. Brooks-Cole, Salt Lake City, UT

    Google Scholar 

  • Webb GA, Belton PS, Gill AM, Delgadillo I (eds) (2001) Magnetic resonance in food science: a view to the future. The Royal Society of Chemistry, Cambridge, England

    Google Scholar 

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Correspondence to Bradley L. Reuhs .

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Reuhs, B.L., Simsek, S. (2017). Nuclear Magnetic Resonance. In: Nielsen, S.S. (eds) Food Analysis. Food Science Text Series. Springer, Cham. https://doi.org/10.1007/978-3-319-45776-5_10

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