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The Small Intestine as a Target for Radiation

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Environmental Radiation Effects on Mammals

Abstract

Chapter 3 is devoted to the development and thorough study of the biologically motivated mathematical model, which describes the dynamics of the small intestinal epithelium in nonirradiated and acutely/chronically irradiated mammals. The model is implemented as the system of nonlinear differential equations. Their variables and constant parameters have real biological meaning that provides successful identification and verification of the model on hand. It is demonstrated that the predictions the model agree, on qualitative and quantitative levels, with the respective experimental data for rodents. All this testifies to the efficiency of employment of the developed model, after the appropriate identification, in investigation and prediction of radiation effects on the small intestinal epithelium system in humans.

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Authors and Affiliations

  1. Research and Technical Center of Radiation-Chemical Safety and Hygiene, Moscow, Russian Federation

    Olga A. Smirnova

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  1. Olga A. Smirnova
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Smirnova, O.A. (2017). The Small Intestine as a Target for Radiation. In: Environmental Radiation Effects on Mammals. Springer, Cham. https://doi.org/10.1007/978-3-319-45761-1_3

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