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Cutaneous Adnexal Neoplasms pp 55–65Cite as

Syringocystadenoma Papilliferum

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Abstract

Syringocystadenoma papilliferum usually presents as a solitary papule, nodule, or plaque on the scalp, and, in many cases, the lesion is associated with a nevus of Jadassohn.

Histopathologically, the lesion appears as a crateriform lesion, composed of one or several dilated and confluent hair follicle infundibula connected with numerous papillary structures. These papillae are lined by two layers of epithelial cells: the luminal layer composed of columnar epithelial cells, with signs of decapitation secretion, and the outer layer made up of cuboidal cells. The stroma of the papillary structures shows numerous dilated capillaries and a dense inflammatory infiltrate composed predominantly of plasma cells.

Syringocystadenoma papilliferum is a benign hamartoma, but there are some cases of syringocystadenocarcinoma papilliferum which have developed on a pre-existing syringocystadenoma papilliferum.

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Authors and Affiliations

  1. Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain

    Luis Requena

  2. Department of Pathology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA

    Omar Sangüeza

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  1. Luis Requena
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  2. Omar Sangüeza
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Requena, L., Sangüeza, O. (2017). Syringocystadenoma Papilliferum. In: Cutaneous Adnexal Neoplasms. Springer, Cham. https://doi.org/10.1007/978-3-319-45704-8_7

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  • DOI: https://doi.org/10.1007/978-3-319-45704-8_7

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