Abstract
The photodynamic therapy stands out, not only for the few adverse effects to the veterinary patient but also for presenting environmental safety, not inducing microbial resistance and reducing generation of residual drugs on products intended for human consumption. After understanding the full potential of this new therapeutic modality through the previous chapters, the purpose of this chapter is to cover the main aspects to be considered by veterinarians to move PDT to clinical practice. It will be presented how the light source and photosensitizers should be chosen as well as the application modes for both antimicrobial and cancer PDT. Biosafety will also be addressed.
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References
Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci. 2004;3(5):436–50.
Jori G, Fabris C, Soncin M, Ferro S, Coppellotti O, Dei D, et al. Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications. Lasers Surg Med. 2006;38(5):468–81.
Dougherty TJ, Kaufman JE, Goldfarb A, Weishaupt KR, Boyle D, Mittleman A. Photoradiation therapy for the treatment of malignant tumors. Cancer Res. 1978;38(8):2628–35.
Wilson BC, Patterson MS. The physics, biophysics and technology of photodynamic therapy. Phys Med Biol. 2008;53(9):R61–109.
Enk CD, Nasereddin A, Alper R, Dan-Goor M, Jaffe CL, Wulf HC. Cutaneous leishmaniasis responds to daylight-activated photodynamic therapy: proof of concept for a novel self-administered therapeutic modality. Br J Dermatol. 2015;172(5):1364–70.
Yin R, Hamblin MR. Antimicrobial photosensitizers: drug discovery under the spotlight. Curr Med Chem. 2015;22(18):2159–85.
Savino F, Maccario S, Guidi C, Castagno E, Farinasso D, Cresi F, et al. Methemoglobinemia caused by the ingestion of courgette soup given in order to resolve constipation in two formula-fed infants. Ann Nutr Metab. 2006;50(4):368–71.
Betten DP, Vohra RB, Cook MD, Matteucci MJ, Clark RF. Antidote use in the critically ill poisoned patient. J Intensive Care Med. 2006;21(5):255–77.
Golshan M, Nakhlis F. Can methylene blue only be used in sentinel lymph node biopsy for breast cancer? Breast J. 2006;12(5):428–30.
Ormond A, Freeman H. Dye sensitizers for photodynamic therapy. Materials (Basel). 2013;6(3):817–40.
Sekkat N, van den Bergh H, Nyokong T, Lange N. Like a bolt from the blue: phthalocyanines in biomedical optics. Molecules. 2012;17(1):98–144.
Peaston AE, Leach MW, Higgins RJ. Photodynamic therapy for nasal and aural squamous cell carcinoma in cats. J Am Vet Med Assoc. 1993;202(8):1261–5.
Buchholz J, Walt H. Veterinary photodynamic therapy: a review. Photodiagnosis Photodyn Ther. 2013;10(4):342–7.
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Nascimento, C.L., Sellera, F.P., Ribeiro, M.S. (2016). How to Enter PDT in Clinical Practice?. In: Sellera, F., Nascimento, C., Ribeiro, M. (eds) Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-45007-0_8
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DOI: https://doi.org/10.1007/978-3-319-45007-0_8
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