Skip to main content

Management of Catheter-Related Bloodstream Infections in Cancer Patients

  • Chapter
  • First Online:
Book cover Surgical Emergencies in the Cancer Patient

Abstract

Cancer patients commonly require long-term central venous catheters. These catheters are used to repeatedly administer systemic antineoplastic treatments, blood draws, and at times hydration, parental nutrition, blood products, and antibiotics. Long-term retention of central venous catheters, defined as indwelling catheter for greater than 14-day duration, is associated with significant morbidity (Infect Drug Resist 7:25–35, 2014). Most common catheter-related late complications are potentially life-threatening bloodstream infections. While proper placement techniques, standardization of sterile procedures, and improved devices can decrease catheter-related bloodstream infections, every surgical oncologist will, however, still encounter this complication.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bustos C, Aguinaga A, Carcoma-Torre F, Luis Del Pozo J. Long-term catheterization: current approaches in the diagnosis and treatment of port-related infections. Infect Drug Resist. 2014;7:25–35.

    PubMed  PubMed Central  Google Scholar 

  2. Maki DG, Kluger DM, Crnich CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc. 2006;81(9):1159–71.

    Article  PubMed  Google Scholar 

  3. Schwartz RE, Coit DG, Groeger JS. Transcutaneously tunneled central venous lines in cancer patients: an analysis of device-related morbidity factors based on prospective data collection. Ann Surg Oncol. 2000;7(6):441–9.

    Article  Google Scholar 

  4. Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O’Grady NP, Raad II, Rijnders BJ, Sherertz RJ, Warren DK. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;49:1–45.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Astagneau P, Maugat S, Tran-Minh T, Douard MC, Longuet P, Maslo C, Patte R, Macrez A, Brucker G. Long-term central venous catheter infection in HIV-infected and cancer patients: a multicenter cohort study. Infect Control Hosp Epidemiol. 1999;20:494–8.

    Article  CAS  PubMed  Google Scholar 

  6. Samaras P, Dold S, Braun J, Kestenholz P, Breitenstein S, Imhof A, Renner C, Stenner-Liewen F, Pestalozzi BC. Infectious port complications are more frequent in younger patients with hematologic malignancies than in solid tumor patients. Oncology. 2008;74:237–44.

    Article  PubMed  Google Scholar 

  7. Sehirali S, Inal MM, Ozsezgin S, Sanci M, Atli O, Nayki C, Yildirim Y, Tinar S. A randomized prospective study of comparison of reservoir ports versus conventional vascular access in advanced-stage ovarian carcinoma cases treated with chemotherapy. Int J Gynecol Cancer. 2005;15:228–32.

    Article  CAS  PubMed  Google Scholar 

  8. Marra AR, Opilla M, Edmond MB, Kirby DF. Epidemiology of bloodstream infections in patients receiving long-term total parenteral nutrition. J Clin Gastroenterol. 2007;41(1):19–28.

    Article  PubMed  Google Scholar 

  9. Brun-Buisson C, Abrouk F, Legrand P, Huet Y, Larabi S, Rapin M. Diagnosis of central venous catheter-related sepsis. Critical level of quantitative tip cultures. Arch Intern Med. 1987;147:873–7.

    Article  CAS  PubMed  Google Scholar 

  10. Blot F, Nitenberg G, Chachaty E, Raynard B, Germann N, Antoun S, Laplanche A, Brun-Buisson C, Tancrede C. Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures. Lancet. 1999;354:1071–7.

    Article  CAS  PubMed  Google Scholar 

  11. Guembe M, Rodríguez-Créixems M, Sánchez-Carrillo C, Pérez-Parra A, Martín-Rabadán P, Bouza E. How many lumens should be cultured in the conservative diagnosis of catheter-related bloodstream infections? Clin Infect Dis. 2010;50(12):1575–9.

    Article  PubMed  Google Scholar 

  12. Rijnders BJ, Van Wijngaerden E, Vandecasteele SJ, Stas M, Peetermans WE. Treatment of long-term intravascular catheter-related bacteraemia with antibiotic lock: randomized, placebo-controlled trial. J Antimicrob Chemother. 2005;55:90–4.

    Article  CAS  PubMed  Google Scholar 

  13. Fortun J, Grill F, Martin-Davila P, et al. Treatment of long-term intravascular catheter-related bacteraemia with antibiotic-lock therapy. J Antimicrob Chemother. 2006;58:816–21.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yanghee Woo M.D., F.A.C.S. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Woo, Y. (2017). Management of Catheter-Related Bloodstream Infections in Cancer Patients. In: Fong, Y., Kauffmann, R., Marcinkowski, E., Singh, G., Schoellhammer, H. (eds) Surgical Emergencies in the Cancer Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-44025-5_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-44025-5_23

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44023-1

  • Online ISBN: 978-3-319-44025-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics