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Success in Academic Surgery pp 25–31Cite as

Reviewing the Literature, Developing a Hypothesis, Study Design

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Part of the book series: Success in Academic Surgery ((SIAS))

Abstract

Rigorous research investigation requires a thorough review of the literature on the topic of interest. This promotes development of an original, relevant and feasible hypothesis. Design of an optimal study to test the hypothesis then requires adequate power, freedom from bias, and conduct within a reasonable timeframe with resources available to the investigator.

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Suggested Additional Reading

  1. Friedman LM, et al. Fundamentals of clinical trials. 4th ed. 2010.

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  2. Hulley SB. Designing clinical research. 4th ed. 2013.

    Google Scholar 

  3. Penson, Wei. Clinical research methods for surgeons. 2006.

    Google Scholar 

  4. Piantadosi S. Clinical trials: a methodological perspective. 2nd ed. 2005.

    Google Scholar 

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Acknowledgements

Carl Schmidt, MD, MSCI

Assistant Professor Surgery

The Ohio State University

Financial Support

Indiana Genomics Initiative (INGEN) of Indiana University. INGEN is supported in part by Lilly Endowment Inc. (CMS)

Author information

Authors and Affiliations

  1. Department of Surgery, Biochemistry and Molecular Biology, Indiana University School of Medicine, 980 W Walnut St C522, Indianapolis, IN, 46202, USA

    Rosalie Carr M.D. & C. Max Schmidt M.D., Ph.D., M.B.A., F.A.C.S.

Authors
  1. Rosalie Carr M.D.
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  2. C. Max Schmidt M.D., Ph.D., M.B.A., F.A.C.S.
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Editor information

Editors and Affiliations

  1. Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA

    Herbert Chen

  2. Department of Surgery, The University of Texas Health Science Centre, Houston, Texas, USA

    Lillian S. Kao

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Carr, R., Schmidt, C.M. (2017). Reviewing the Literature, Developing a Hypothesis, Study Design. In: Chen, H., Kao, L. (eds) Success in Academic Surgery. Success in Academic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-43952-5_3

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  • DOI: https://doi.org/10.1007/978-3-319-43952-5_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-43951-8

  • Online ISBN: 978-3-319-43952-5

  • eBook Packages: MedicineMedicine (R0)

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