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The Pediatric Thyroid Nodule and Papillary Thyroid Cancer Management

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Management of Thyroid Nodules and Differentiated Thyroid Cancer

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Abstract

Pediatric thyroid cancer is a rare disease with an excellent prognosis. Compared with adults, epithelial-derived differentiated thyroid cancer (DTC), which includes papillary (PTC), presents at more advanced stages in children and is associated with higher rates of recurrence. Because of its uncommon occurrence, randomized trials have not been applied to test best care options in children. Even in adults that have a tenfold or higher incidence of thyroid cancer than children, few prospective trials have been executed to compare treatment approaches. We recognize that treatment recommendations have changed over the past few decades and will continue to do so. Reflecting the aggressiveness of pediatric thyroid cancer, high recurrence rates, and the problems associated with decades of long-term follow-up, a premium should be placed on treatments that minimize risk of recurrence and the adverse effects of treatments and facilitate follow-up. We recommend long-term follow-up, since disease can recur decades after initial therapy. Considering the complexity of DTC management and the potential complications associated with therapy, it is essential that pediatric DTC be managed by physicians with expertise in this area.

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Authors and Affiliations

  1. Department of Pediatrics, University of Florida College of Medicine, 1600 SW Archer Road – Room R1-118, Gainesville, FL, 32610-0296, USA

    Scott A. Rivkees MD

  2. Department of Surgery, Yale University School of Medicine, New Haven, CT, USA

    Catherine A. Dinauer MD

  3. Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA

    Catherine A. Dinauer MD

Authors
  1. Scott A. Rivkees MD
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  2. Catherine A. Dinauer MD
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Correspondence to Scott A. Rivkees MD .

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Editors and Affiliations

  1. Endocrine Surgery, Department of Surgery, Duke University Medical Center Duke Cancer Institute, Durham, North Carolina, USA

    Sanziana A. Roman

  2. Department of Surgery, Duke University Medical Center Duke Cancer Institute, Durham, North Carolina, USA

    Julie Ann Sosa

  3. Division of Surgical Oncology and Endocrine Surgery, Vanderbilt Endocrine Surgery Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA

    Carmen C. Solórzano

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Rivkees, S.A., Dinauer, C.A. (2017). The Pediatric Thyroid Nodule and Papillary Thyroid Cancer Management. In: Roman, S., Sosa, J., Solórzano, C. (eds) Management of Thyroid Nodules and Differentiated Thyroid Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-43618-0_13

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