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Update on De-intensification and Intensification Studies in HPV

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HPV Infection in Head and Neck Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 206))

Abstract

In this chapter, we discuss de-esclation of treatment for patients with HPV-positive disease. We discuss the rationale for de-escalation (why de-escalate?), patient selection criteria (who to de-esclate?) and what the treatment options for de-esclation are and the studies that are currently being run in those areas (how to de-escalate?). We stress the importance of clinicians NOT changing the management of oropharyngeal cancer patients outside clinical trials, and encourage them to recruit to the ongoing studies.

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Author information

Authors and Affiliations

  1. Chair of Head and Neck Surgery, School of Cancer Sciences, University of Birmingham, Birmingham, England, UK

    Hisham Mehanna

  2. Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, England, UK

    Hisham Mehanna

Authors
  1. Hisham Mehanna
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Correspondence to Hisham Mehanna .

Editor information

Editors and Affiliations

  1. Department of Head and Neck Surgery, Poznan University of Medical Sciences, The Greater Poland Cancer Centre, Poznań, Poland

    Wojciech Golusiński

  2. Department of Otolaryngology-Head and Neck Surgery, VU University Medical Center/Cancer Center Amsterdam, Amsterdam, The Netherlands

    C. René Leemans

  3. Dept. of Head Medicine and Oral Health, University of Leipzig Clinic of Otolaryngology, Leipzig, Germany

    Andreas Dietz

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© 2017 Springer International Publishing Switzerland

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Mehanna, H. (2017). Update on De-intensification and Intensification Studies in HPV. In: Golusiński, W., Leemans, C., Dietz, A. (eds) HPV Infection in Head and Neck Cancer. Recent Results in Cancer Research, vol 206. Springer, Cham. https://doi.org/10.1007/978-3-319-43580-0_20

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  • DOI: https://doi.org/10.1007/978-3-319-43580-0_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-43578-7

  • Online ISBN: 978-3-319-43580-0

  • eBook Packages: MedicineMedicine (R0)

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