Skip to main content
SpringerLink
Log in

The Role of Surgery in the Management of Recurrent Oropharyngeal Cancer

  • Chapter
  • First Online:
HPV Infection in Head and Neck Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 206))

Abstract

The incidence of oropharyngeal squamous cell carcinoma (OPSCC) continues to rise worldwide at a dramatic pace, buoyed by the predominance of human papilloma virus (HPV) driven disease (Panwar et al. 2014). While the outcomes of patients with HPV-positive OPSCC are dramatically improved compared to HPV-negative OPSCC, treatment failures do occur. The result is an inevitable rise in the incidence of recurrent OPSCC. Since the majority of incident OPSCC cases are treated with some form of radiation therapy (primary or adjuvant), surgery remains the backbone of treatment for recurrent OPSCC. This section will focus on options for surgical management of recurrent OPSCC.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Agra IM, Carvalho AL, Ulbrich FS et al (2006) Prognostic factors in salvage surgery for recurrent oral and oropharyngeal cancer. Head Neck 28:107–113

    Article  PubMed  Google Scholar 

  • Babin R, Calcaterra TC (1976) The lip-splitting approach to resection of oropharyngeal cancer. J Surg Oncol 8:433–436

    Article  CAS  PubMed  Google Scholar 

  • Brickman D, Gross ND (2014) Robotic approaches to the pharynx: tonsil cancer. Otolaryngol Clin North Am 47:359–372

    Article  PubMed  Google Scholar 

  • Chia SH, Gross ND, Richmon JD (2013) Surgeon experience and complications with transoral robotic surgery (tors). Otolaryngol Head Neck Surg 149:885–892

    Article  PubMed  Google Scholar 

  • de Almeida JR, Park RC, Villanueva NL, Miles BA, Teng MS, Genden EM (2014) Reconstructive algorithm and classification system for transoral oropharyngeal defects. Head Neck 36:934–941

    Article  PubMed  Google Scholar 

  • Ford SE, Brandwein-Gensler M, Carroll WR, Rosenthal EL, Magnuson JS (2014) Transoral robotic versus open surgical approaches to oropharyngeal squamous cell carcinoma by human papillomavirus status. Otolaryngol Head Neck Surg 151:606–611

    Article  PubMed  Google Scholar 

  • Moore EJ, Hinni ML (2013) Critical review: transoral laser microsurgery and robotic-assisted surgery for oropharynx cancer including human papillomavirus-related cancer. Int J Radiat Oncol Biol Phys 85:1163–1167

    Article  PubMed  Google Scholar 

  • Moore EJ, Olsen SM, Laborde RR et al (2012) Long-term functional and oncologic results of transoral robotic surgery for oropharyngeal squamous cell carcinoma. Mayo Clin Proc 87:219–225

    Article  PubMed  PubMed Central  Google Scholar 

  • Nasri S, Oh Y, Calcaterra TC (1996) Transpharyngeal approach to base of tongue tumors: a comparative study. Laryngoscope 106:945–950

    Article  CAS  PubMed  Google Scholar 

  • National Comprehensive Cancer Network (NCCN) (2015) Guidelines Head and Neck Cancers Version 1.2015. 5-12-2015. Ref Type: Online Source

    Google Scholar 

  • Panwar A, Batra R, Lydiatt WM, Ganti AK (2014) Human papilloma virus positive oropharyngeal squamous cell carcinoma: a growing epidemic. Cancer Treat Rev 40:215–219

    Article  PubMed  Google Scholar 

  • Selber JC, Sarhane KA, Ibrahim AE, Holsinger FC (2014) Transoral robotic reconstructive surgery. Semin Plast Surg 28:35–38

    Article  PubMed  PubMed Central  Google Scholar 

  • Sessions DG (1983) Surgical resection and reconstruction for cancer of the base of the tongue. Otolaryngol Clin North Am 16:309–329

    CAS  PubMed  Google Scholar 

  • Weinstein GS, Quon H, O’Malley BW Jr, Kim GG, Cohen MA (2010) Selective neck dissection and deintensified postoperative radiation and chemotherapy for oropharyngeal cancer: a subset analysis of the University of Pennsylvania transoral robotic surgery trial. Laryngoscope 120:1749–1755

    Article  PubMed  Google Scholar 

  • Weinstein GS, O’Malley BW, Magnuson JS et al (2012) Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins. The Laryngoscope 122:1701–1707

    Article  PubMed  Google Scholar 

  • White HN, Frederick J, Zimmerman T, Carroll WR, Magnuson JS (2013a) Learning curve for transoral robotic surgery: a 4-year analysis. JAMA Otolaryngol Head Neck Surg 139:564–567

    Article  PubMed  Google Scholar 

  • White H, Ford S, Bush B et al (2013b) Salvage surgery for recurrent cancers of the oropharynx: comparing TORS with standard open surgical approaches. JAMA Otolaryngol Head Neck Surg 139:773–778

    Article  PubMed  Google Scholar 

  • Zeitels SM, Vaughan CW, Ruh S (1991) Suprahyoid pharyngotomy for oropharynx cancer including the tongue base. Arch Otolaryngol Head Neck Surg 117:757–760

    Article  CAS  PubMed  Google Scholar 

Download references

Potential Conflict(s) of Interest

Gross: Scientific advisor (unpaid), MedRobotics

Gross: Scientific advisor (unpaid), Intuitive Surgical, Inc.

Author information

Authors and Affiliations

  1. Department Head and Neck Surgery, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1445, Houston, TX, 77030, USA

    Neil D. Gross & Ehab Y. Hanna

Authors
  1. Neil D. Gross
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ehab Y. Hanna
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Neil D. Gross .

Editor information

Editors and Affiliations

  1. Department of Head and Neck Surgery, Poznan University of Medical Sciences, The Greater Poland Cancer Centre, Poznań, Poland

    Wojciech Golusiński

  2. Department of Otolaryngology-Head and Neck Surgery, VU University Medical Center/Cancer Center Amsterdam, Amsterdam, The Netherlands

    C. René Leemans

  3. Dept. of Head Medicine and Oral Health, University of Leipzig Clinic of Otolaryngology, Leipzig, Germany

    Andreas Dietz

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Gross, N.D., Hanna, E.Y. (2017). The Role of Surgery in the Management of Recurrent Oropharyngeal Cancer. In: Golusiński, W., Leemans, C., Dietz, A. (eds) HPV Infection in Head and Neck Cancer. Recent Results in Cancer Research, vol 206. Springer, Cham. https://doi.org/10.1007/978-3-319-43580-0_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-43580-0_15

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-43578-7

  • Online ISBN: 978-3-319-43580-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation