Abstract
Though a relatively rare disease (with an estimated prevalence of 0.5–1 new cases per 100,000 population a year, and with no clear age predilection), achalasia is the most common motor disorder of the esophagus. Its pathophysiology consists of the loss of esophageal body peristalsis and an impaired lower esophageal sphincter (LES) relaxation, resulting in a residual pressure gradient between the esophagus and the stomach during swallowing, which gives rise to a functional obstruction at the gastro-esophageal junction.
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Zaninotto, G., Costantini, M. (2017). Motility Disorders. In: Bonjer, H. (eds) Surgical Principles of Minimally Invasive Procedures. Springer, Cham. https://doi.org/10.1007/978-3-319-43196-3_7
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DOI: https://doi.org/10.1007/978-3-319-43196-3_7
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