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An Omics Approach to Transition Cow Immunity

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Periparturient Diseases of Dairy Cows

Abstract

Traditionally, research of transition cow immunity has focused on a reductionist approach trying to pinpoint a single factor that causes periparturient immunosuppression. Both previous and recent research has revealed that this phenomenon has a multifactorial etiology and that our current understanding remains insufficient to properly manage the high disease incidence at this time. In taking a systems biology approach through omics technologies we will be able to develop a fundamental understanding of the causal agents and the mechanisms underlying immunosuppression where preceding technologies have failed. Moreover, these new technologies have the potential to help us develop management techniques to restore the normality of immune response during transition period and lower the increased disease incidence that follows immunosuppression. It should be noted that currently application of omics approaches to transition cow immunity are at their pioneering level and further research is warranted to realize the importance of these sciences in the field of cow health and immunity.

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Authors and Affiliations

  1. Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada, T6G 2P5

    Emily F. Eckel Ph.D. & Burim N. Ametaj D.V.M., Ph.D., Ph.D.

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  1. Emily F. Eckel Ph.D.
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  2. Burim N. Ametaj D.V.M., Ph.D., Ph.D.
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Correspondence to Emily F. Eckel Ph.D. .

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  1. Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada

    Burim N. Ametaj

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Eckel, E.F., Ametaj, B.N. (2017). An Omics Approach to Transition Cow Immunity. In: Ametaj, B. (eds) Periparturient Diseases of Dairy Cows. Springer, Cham. https://doi.org/10.1007/978-3-319-43033-1_3

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