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Gaps in Our Biomarker Armamentarium: What Novel Biomarkers Might Be Synergistic in Patients with Acute Disease

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Cardiac Biomarkers

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Abstract

We have seen dramatic improvements of the acute cardiac care in the last 20 years, which have led to a substantial reduction in short and long term mortality after acute myocardial infarction (AMI) as well as after heart failure (HF) [1, 2]. These impressive successes have been achieved mainly by improved treatments but also through improved diagnostic methods. During this time period we have got access to some very strong new biomarkers, cardiac troponins (cardiac troponin I and cardiac troponin I) and natriuretic peptides (BNP and NT-proBNP). Their success and widespread use are based upon their excellent diagnostic properties rather than their similarly excellent prognostic properties. The introduction and development of more and more sensitive cTn assays have revolutionized the diagnosis of AMI.

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Authors and Affiliations

  1. Uppsala Clinical Research Center and Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden

    Bertil Lindahl MD, PhD

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  1. Bertil Lindahl MD, PhD
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Correspondence to Bertil Lindahl MD, PhD .

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Editors and Affiliations

  1. Division of Cardiovascular Medicine, University of California San Diego Division of Cardiovascular Medicine, La Jolla, California, USA

    Alan S. Maisel

  2. Cardiology Department, Mayo Clinic Cardiology Department, ROCHESTER, Minnesota, USA

    Allan S. Jaffe

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© 2016 Springer International Publishing Switzerland

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Lindahl, B. (2016). Gaps in Our Biomarker Armamentarium: What Novel Biomarkers Might Be Synergistic in Patients with Acute Disease. In: Maisel, A., Jaffe, A. (eds) Cardiac Biomarkers. Springer, Cham. https://doi.org/10.1007/978-3-319-42982-3_20

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  • DOI: https://doi.org/10.1007/978-3-319-42982-3_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42980-9

  • Online ISBN: 978-3-319-42982-3

  • eBook Packages: MedicineMedicine (R0)

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