Abstract
Interest in tailored therapeutics has led to innovations in trial design and analysis. Trials now range from traditional overall population trials with exploratory subgroup analysis to single population tailoring trials, to multipopulation tailoring trials. This paper presents an overview of the trial options and provides a framework for decision making in confirmatory multipopulation tailoring trials.
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Millen, B.A. (2016). A Statistical Decision Framework Applicable to Multipopulation Tailoring Trials. In: Lin, J., Wang, B., Hu, X., Chen, K., Liu, R. (eds) Statistical Applications from Clinical Trials and Personalized Medicine to Finance and Business Analytics. ICSA Book Series in Statistics. Springer, Cham. https://doi.org/10.1007/978-3-319-42568-9_10
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DOI: https://doi.org/10.1007/978-3-319-42568-9_10
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