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MRI and Preoperative Staging in Women Newly Diagnosed with Breast Cancer

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Breast Oncology: Techniques, Indications, and Interpretation

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Abstract

Breast magnetic resonance imaging (MRI) is well established as the most sensitive and accurate imaging modality for local-regional staging of breast cancer. It is superior to clinical examination, mammography and ultrasound, alone or combined, in delineation of size and extent of tumor, additional sites of disease, pectoralis muscle and chest wall invasion, nipple and skin involvement, as well as lymph node metastasis. However, the use of MRI for staging of newly diagnosed breast cancer has been a subject of intense debate, because the expected clinical benefits of improved staging by MRI have been called into question. The clinical outcome literature on the benefits of preoperative MRI shows conflicting results regarding re-excision rates and local recurrence rates, and the data do not support a benefit on long-term survival. There are also concerns that preoperative MRI causes delayed definitive therapy and increased mastectomy rates. This chapter details the advantages of MRI staging of newly diagnosed breast cancer, discusses the benefit of MRI staging for a subset of patients and certain clinical scenarios, and reviews the current literature with respect to the pros and cons of MRI staging.

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Authors and Affiliations

  1. Department of Radiology, University of Cincinnati Medical Center, 234 Goodman Street, Mail Location 0772, Cincinnati, OH, 45219-2316, USA

    Su-Ju Lee MD & Mary C. Mahoney MD, FACR

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  1. Su-Ju Lee MD
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  2. Mary C. Mahoney MD, FACR
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  1. Department of Radiology, New York University Langone Medical Center New York University School of Medicine, New York, USA

    Samantha L. Heller

  2. Department of Radiology, New York University Langone Medical Center New York University School of Medicine, New York, USA

    Linda Moy

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Lee, SJ., Mahoney, M.C. (2017). MRI and Preoperative Staging in Women Newly Diagnosed with Breast Cancer. In: Heller, S., Moy, L. (eds) Breast Oncology: Techniques, Indications, and Interpretation. Springer, Cham. https://doi.org/10.1007/978-3-319-42563-4_4

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