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Abbreviated Breast MRI

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Breast Oncology: Techniques, Indications, and Interpretation

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Abstract

Breast MRI demonstrates high sensitivity for breast cancer detection, beyond that of mammography and ultrasound. Numerous factors limit the widespread application of MRI as a screening modality for all women, including time-consuming protocols which may occupy the MRI system for 30–60 min, and which are costly, difficult for patients and limit clinical accessibility. Recently researchers have questioned which MR sequences are truly necessary in the screening setting to achieve the desired sensitivity of a screening examination. The definition of an abbreviated MR protocol varies from study to study and research is ongoing to optimize such a protocol. Possibilities include limiting the exam to one post-contrast sequence, utilizing T2-weighted or diffusion weighted imaging (DWI) or employing time-resolved angiography with stochastic trajectories (TWIST) sequences. Decreased image acquisition and reading time in the screening MRI setting could potentially decrease cost and increase women’s access to screening breast MRI without sacrificing diagnostic accuracy and cancer yield.

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References

  1. Morris EA, Liberman L, Ballon DJ, Robson M, Abramson AF, Heerdt A, et al. MRI of occult breast carcinoma in a high-risk population. Am J Roentgenol. 2003;181:619–26.

    Article  Google Scholar 

  2. Berg WA, Zhang Z, Lehrer D, Jong RA, Pisano ED, Barr RG, et al. Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk. JAMA. 2012;307:1394–404.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Lehman CD, Isaacs C, Schnall MD. Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screen study. Radiology. 2007;244(2):381–8.

    Article  PubMed  Google Scholar 

  4. Saslow D, Boetes C, Burke W, et al. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007;57(2):75–89.

    Article  PubMed  Google Scholar 

  5. Sardanelli F, Podo F, Santoro F, et al. Multi-center surveillance of women at high genetic breast cancer risk using mammography, ultrasonography, and contrast-enhanced magnetic resonance imaging (the high breast cancer risk Italian 1 study): final results. Invest Radiol. 2011;46:94–105.

    Article  PubMed  Google Scholar 

  6. Lehman CD, Gatsonis C, Kuhl CK, et al. MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer. N Engl J Med. 2007;356:1295–303.

    Article  CAS  PubMed  Google Scholar 

  7. Warner E, Plewes DB, Hill KA, et al. Surveillance of BRCA 1 and BRCA 2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination. JAMA. 2004;292:1317–25.

    Article  CAS  PubMed  Google Scholar 

  8. Kriege M, Brekelmans CT, Boetes C, et al. Efficacy of MRI and mammography for breast cancer screening in women with a familial or genetic predisposition. N Engl J Med. 2004;351:427–37.

    Article  CAS  PubMed  Google Scholar 

  9. Kuhl CK, Schrading S, Leutner CC, et al. Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer. J Clin Oncol. 2005;23:8469–76.

    Article  PubMed  Google Scholar 

  10. Leach MO, Boggis CR, Dixon AK, et al. Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS). Lancet. 2005;365:1769–78.

    Article  CAS  PubMed  Google Scholar 

  11. Lehman CD, Blume JD, Weatherall P, et al. Screening women at high risk for breast cancer with mammography and magnetic resonance imaging. Cancer. 2005;103:1898–905.

    Article  PubMed  Google Scholar 

  12. Passaperuma K, Warner E, Causer PA, et al. Long-term results of screening with magnetic resonance imaging in women with BRCA mutations. Br J Cancer. 2012;107:24–30.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Warner E, Hill K, Causer P, et al. Prospective study of breast cancer incidence in women with a BRCA 1 or BRCA 2 mutation under surveillance with and without magnetic resonance imaging. J Clin Oncol. 2011;29:1664–9.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Sickles EA. The use of breast imaging to screen women at high risk for cancer. Radiol Clin North Am. 2010;48:859–78.

    Article  PubMed  Google Scholar 

  15. Ahern CH, Shih YC, Dong W, et al. Cost-effectiveness of alternative strategies for integrating MRI into breast cancer screening for women at high risk. Br J Cancer. 2014;111:1542–51.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Feig S. Cost-effectiveness of mammography, MRI, and ultrasonography for breast cancer screening. Radiol Clin North Am. 2010;48:879–91.

    Article  PubMed  Google Scholar 

  17. Moore SG, Shenoy PJ, Fanucchi L, et al. Cost-effectiveness of MRI compared to mammography for breast cancer screening in a high risk population. BMC Health Serv Res. 2009;9:9.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Pataky R, Armstrong L, Chia S, et al. Cost-effectiveness of MRI for breast cancer screening in BRCA ½ mutation carriers. BMC Cancer. 2013;13:339.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Taneja C, Edelsberg J, Weycker D, et al. Cost-effectiveness of breast cancer screening with contrast-enhanced MRI in high-risk women. J Am Coll Radiol. 2009;6:171–9.

    Article  PubMed  Google Scholar 

  20. Grimm LJ, Soo MS, Yoon S, Kim C, Ghate SV, Johnson KS. Abbreviated screening protocol for breast MRI: a feasibility study. Acad Radiol. 2015;22:1157–62.

    Article  PubMed  Google Scholar 

  21. Lowry KP, Lee JM, Kong CY, et al. Annual screening strategies in BRCA 1 and BRCA 2 gene mutation carriers: a comparative effectiveness analysis. Cancer. 2012;118:2021–30.

    Article  PubMed  Google Scholar 

  22. Cott Chubiz JE, Lee JM, Gilmore ME, et al. Cost-effectiveness of alternating magnetic resonance imaging and digital mammography screening in BRCA 1 and BRCA 2 gene mutation carriers. Cancer. 2013;119:1266–76.

    Article  PubMed  Google Scholar 

  23. Ivanov EN, Pogromsky AY, Van Den Brink JS, et al. Optimization of duty cycles for MRI scanners. Concepts Magn Reson Part B Magn Reson Eng. 2010;37B:180–92.

    Article  Google Scholar 

  24. Carpenter AP, Leemis LM, Papir AS, et al. Managing magnetic resonance imaging machines: support tools for scheduling and planning. Health Care Manag Sci. 2011;14:158–73.

    Article  PubMed  Google Scholar 

  25. Wernli KJ, Demartini WB, Ichikawa L, et al. Patterns of breast magnetic imaging use in community practice. JAMA Intern Med. 2014;174:125–32.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Trimboli RM, Verardi N, Cartia F, Carbonaro LA, Sardanelli F. Breast cancer detection using double reading of unenhanced MRI including T1-weighted, T2-weighted STIR, and diffusion-weighted imaging: a proof of concept study. Am J Roentgenol. 2014;203:674–81.

    Article  Google Scholar 

  27. Wilson JMG, Junger G. Principles and practice of screening for disease. Geneva, Switzerland: World Health Organization; 1968.

    Google Scholar 

  28. Kuhl CK, Schrading S, Strobel K, Schild HH, Hilgers RD, Beiling HB. Abbreviated breast magnetic resonance imaging (MRI): first postcontrast subtracted images and maximum-intensity projection- a novel approach to breast cancer screening with MRI. J Clin Oncol. 2014;32:2304–10.

    Article  PubMed  Google Scholar 

  29. Garg AS, Rapelyea JA, Rechtman LR, et al. Full-field digital mammographic interpretation with prior analog versus prior digitized analog mammography: Time for interpretation. Am J Roentgenol. 2011;196:1436–8.

    Article  Google Scholar 

  30. Tchou PM, Haygood TM, Atkinson EN, et al. Interpretation time of computer-aided detection at screening mammography. Radiology. 2010;257:40–6.

    Article  PubMed  Google Scholar 

  31. Berg WA, Blume JD, Cormack JB, et al. Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer. JAMA. 2008;299:2151–63.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Mango VL, Morris EA, Dershaw DD, Abramson A, Fry C, Moskowitz CS, Hughes M, Kaplan J, Jochelson M. Abbreviated protocol for breast MRI: are multiple sequences needed for cancer detection? Eur J Radiol. 2015;84:65–70.

    Article  PubMed  Google Scholar 

  33. Lehman CD, Blume JD, DeMartini WB, Hylton NM, Herman B, Schnall MD, et al. Accuracy and interpretation time of computer-aided detection among novice and experience breast MRI readers. Am J Roentgenol. 2013;200:W683–9.

    Article  Google Scholar 

  34. Heacock L, Melsaether AN, Heller SL, et al. Evaluation of a known breast cancer using an abbreviated breast MRI protocol: correlation of imaging characteristics and pathology with lesion detection and conspicuity. Eur J Radiol. 2016;85(4):815–23.

    Article  PubMed  Google Scholar 

  35. Warner E, Messersmith H, Causer P, et al. Systematic review: using magnetic resonance imaging to screen women at high risk for breast cancer. Ann Intern Med. 2008;148:671–9.

    Article  PubMed  Google Scholar 

  36. Peters NH, Borel Rinkes IH, Zuithoff NP, et al. Meta-analysis of MR imaging in the diagnosis of breast lesions. Radiology. 2008;246:116–24.

    Article  PubMed  Google Scholar 

  37. Mann RM, Mus RD, Zelst JV, Geppert C, Karssemeijer N, Platel B. A novel approach to contrast-enhanced breast magnetic resonance imaging for screening: high-resolution ultrafast dynamic imaging. Invest Radiol. 2014;49(9):579–85.

    Article  PubMed  Google Scholar 

  38. Englander SA, Ulug AM, Brem R, Glickson JD, van Zijl PC. Diffusion imaging of human breast. NMR Biomed. 1997;10:348–52.

    Article  CAS  PubMed  Google Scholar 

  39. Woodhams R, Ramadan S, Stanwell P, et al. Diffusion-weighted imaging of the breast: principles and clinical applications. Radiographics. 2011;31:1059–84.

    Article  PubMed  Google Scholar 

  40. Ho JM, Jafferjee N, Covarrubias GM, et al. Dense breasts: a review of reporting legislation and available supplemental screening options. Am J Roentgenol. 2014;203:449–56.

    Article  Google Scholar 

  41. Freer PE. Mammographic breast density: impact on breast cancer risk and implications for screening. Radiographics. 2015;35(2):302–15.

    Article  PubMed  Google Scholar 

  42. Harvey JA, Bovbjerg VE. Quantitative assessment of mammographic breast density: relationship with breast cancer risk. Radiology. 2004;230:29–41.

    Article  PubMed  Google Scholar 

  43. Sprague BL, Gangnon RE, Burt V, et al. Prevalence of mammographically dense breasts in the United States. J Natl Cancer Inst. 2014;106:1–6.

    Article  Google Scholar 

  44. Riedl CC, Luft N, Bernhart C, et al. Triple-modality screening trial for familial breast cancer underlines the importance of magnetic resonance imaging and questions the role of mammography and ultrasound regardless of patient mutations status, age, and breast density. J Clin Oncol. 2015;33:1128–35.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Victoria Mango MD

  2. Department of Radiology, New York University School of Medicine, New York University Langone Medical Center, Laura and Isaac Perlmutter Cancer Center, New York, NY, USA

    Linda Moy MD

Authors
  1. Victoria Mango MD
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  2. Linda Moy MD
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Correspondence to Victoria Mango MD .

Editor information

Editors and Affiliations

  1. Department of Radiology, New York University Langone Medical Center New York University School of Medicine, New York, USA

    Samantha L. Heller

  2. Department of Radiology, New York University Langone Medical Center New York University School of Medicine, New York, USA

    Linda Moy

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Mango, V., Moy, L. (2017). Abbreviated Breast MRI. In: Heller, S., Moy, L. (eds) Breast Oncology: Techniques, Indications, and Interpretation. Springer, Cham. https://doi.org/10.1007/978-3-319-42563-4_16

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  • DOI: https://doi.org/10.1007/978-3-319-42563-4_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42561-0

  • Online ISBN: 978-3-319-42563-4

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