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Oropharyngeal Cancer

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Target Volume Delineation and Treatment Planning for Particle Therapy

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

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Abstract

Oropharynx tumors (OPC) comprise 24% of all head and neck malignancies, of which the majority arise from the base of the tongue or tonsils [1–4]. Smoking and alcohol use continue to be major risk factors but the prevalence of human papillomavirus (HPV)-associated oropharyngeal cancer has steadily increased by over 200% since the late 1980s [5]. Definitive management involves surgery or radiation therapy (RT) alone for node-negative early-stage tumors or concurrent chemoradiotherapy (CRT) for nodal involvement or locally advanced disease. In surgically managed cases, adjuvant RT or CRT is also often indicated for extracapsular extension or positive surgical margins.

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Authors and Affiliations

  1. Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Suchit H. Patel, Amy J. Xu & Nancy Y. Lee

  2. ProCure Proton Therapy Center, Somerset, NJ, USA

    Kevin Sine & Pamela Fox

Authors
  1. Suchit H. Patel
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  2. Amy J. Xu
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  3. Kevin Sine
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  4. Nancy Y. Lee
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  5. Pamela Fox
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Corresponding author

Correspondence to Nancy Y. Lee .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Nancy Y. Lee

  2. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Jonathan E. Leeman

  3. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Oren Cahlon

  4. Department of Medical Dosimetry, ProCure Proton Therapy Center, Somerset, New Jersey, USA

    Kevin Sine

  5. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Guoliang Jiang

  6. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Jiade J. Lu

  7. Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands

    Stefan Both

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© 2018 Springer International Publishing Switzerland

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Patel, S.H., Xu, A.J., Sine, K., Lee, N.Y., Fox, P. (2018). Oropharyngeal Cancer. In: Lee, N., et al. Target Volume Delineation and Treatment Planning for Particle Therapy. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42478-1_6

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  • DOI: https://doi.org/10.1007/978-3-319-42478-1_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42477-4

  • Online ISBN: 978-3-319-42478-1

  • eBook Packages: MedicineMedicine (R0)

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